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A Phase III Randomised Placebo-controlled Trial Of Mirtazapine As A Pharmacotherapy For Methamphetamine (Ice) Dependence
Funder
National Health and Medical Research Council
Funding Amount
$3,923,009.00
Summary
Crystalline methamphetamine ('ice') is a growing concern in Australia. There are no approved medications that can be used to treat dependence on this drug. This clinical trial will examine whether mirtazapine, a newly identified treatment agent for methamphetamine use, can be used safely and effectively in routine clinical care to manage methamphetamine dependence in Australia.
A Randomised Controlled Trial Of N-acetylcysteine For The Treatment Of Alcohol Use Disorder
Funder
National Health and Medical Research Council
Funding Amount
$1,294,923.00
Summary
We urgently require new treatment strategies. Alcohol misuse is a leading cause of preventable death yet treatment options are limited. We will undertake the first human trial of N-acetylcysteine (NAC) for the management of alcohol use disorder (NAC-AUD). The NAC-AUD project will evaluate the efficacy and cost-efficacy of NAC to reduce alcohol consumption. The results will generate high level clinical evidence for a safe new treatment for a common life threatening disease.