Attention deficit hyperactivity disorde(ADHD) is the most prevalent mental disorder of childhood affecting around 7.5% of Australian school age children. The disorder is strongly genetic and causes significant impairments in academic functioning, family and peer relations with sufferers at increased risk for drug abuse. Identification and characterisation of rare mutations will enhance our knowledge of the neurobiology and advance the search for next generation drug treatments for the disorder.
Impact Of A Sleep Intervention In Children With ADHD: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$384,230.00
Summary
Attention deficit hyperactivity disorder (ADHD) affects up to 7.5% of Australian children. Between 50 and 70% of parents also report sleep problems (eg night waking, insomnia) in their child with ADHD. Such sleep problems are associated with poorer child behaviour, concentration, and school attendance as well as poorer parent mental health and work attendance. This randomised controlled trial will determine whether treating sleep problems in children with ADHD can improve these outcomes.
Thalamocortical Neural Circuits In Higher Order Cognitive And Sensory Processing
Funder
National Health and Medical Research Council
Funding Amount
$370,860.00
Summary
Schizophrenia, depression and dementia are devastating disorders with problems in thinking and sensory perception, but the neural circuits causing these symptoms are not known. I will use new optical and genetic tools in mice to identify the cortical and subcortical circuits required for complex touchscreen tasks, the same tasks to assess patients. Identification of neural circuits that underlie clinical symptoms will increase our understanding of these disorders and improve treatments.
Interactive Attention Training Technology To Enhance Cognitive Skills In Early Life
Funder
National Health and Medical Research Council
Funding Amount
$759,680.00
Summary
Over 30,000 Australian children enter school with attention difficulties each year. We have established a suite of tasks to train attention based on over 20 years of research into neurodevelopmental disorders and attention. These are delivered on tablets in the form of a game known as TALI Train. We now aim to show TALI can improve attention in children with acquired brain injuries and typically developing children for commercialisation to a broad market.
Investigating A Theoretical Model Of Cognitive Control In Children With Attention Deficit Hyperactivity Disorder (ADHD): Informing Our Approach To Cognitive Training.
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
ADHD is the most common childhood developmental disorder, characterised by inattentive and/or hyperactive behaviours. Cognitive control has been highlighted as a potential mediator of ADHD symptoms. This program will i) delineate the relationship between cognitive control and ADHD symptoms, ii) develop a cognitive training intervention to target the underlying mechanisms identified as mediators of ADHD symptoms and iii) evaluate the program in a gold-standard clinical trial.
Developing A Pathophysiological Model For Attention Deficit Hyperactivity Disorder: A Path To Biomarker Discovery
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
Despite the efficacy of stimulant medication in treating attention deficit hyperactivity disorder (ADHD), we lack mechanistic accounts of the neuropathology of ADHD. A major barrier is the lack of human disease models representing clinical symptoms. The derivation of a novel, cell-based ADHD model proposed in this project will shed new light on the physiological bases of ADHD and be a rich resource for biomarker discovery
Contemporary Australian Photography 1980 to the present. Contemporary Australian art photography has burgeoned over the last 25 years but there is no dedicated book length study in the field. This project will fill this gap by putting Australian photography on an international scholarly agenda, which will generate more scholarship on Australian work. It will have enormous national and community benefit for Australian artists, curators and dealers and the general public who are keenly interested ....Contemporary Australian Photography 1980 to the present. Contemporary Australian art photography has burgeoned over the last 25 years but there is no dedicated book length study in the field. This project will fill this gap by putting Australian photography on an international scholarly agenda, which will generate more scholarship on Australian work. It will have enormous national and community benefit for Australian artists, curators and dealers and the general public who are keenly interested in photography. Read moreRead less
Care and Repair: Rethinking Contemporary Curation for Conditions of Crisis. This project aims to address the significant challenge of how to curate contemporary art under conditions of crisis, made acute by the pandemic. It expects to generate new knowledge in the growth areas of contemporary art and curatorial practice, which will be translatable to creative industries seeking solutions to similar challenges. Anticipated outcomes include new models for sustainable, future-oriented creative prac ....Care and Repair: Rethinking Contemporary Curation for Conditions of Crisis. This project aims to address the significant challenge of how to curate contemporary art under conditions of crisis, made acute by the pandemic. It expects to generate new knowledge in the growth areas of contemporary art and curatorial practice, which will be translatable to creative industries seeking solutions to similar challenges. Anticipated outcomes include new models for sustainable, future-oriented creative practice; a stronger international profile for Australian artists and curators; and the establishment of a regional network of artists and curators between Australia and Southeast Asia. This should significantly aid our understanding of how to meet current and future challenges to producers and audiences of contemporary art.Read moreRead less
Cellular Modelling Of Attention Deficit Hyperactivity Disorder (ADHD) Risk Genes
Funder
National Health and Medical Research Council
Funding Amount
$753,746.00
Summary
Attention deficit hyperactivity disorder is a prevalent behavioural disorder affecting 7.4% of Australian children and adolescents. It has a strong genetic component with high heritability estimates (75–90%) comparable to other serious mental illness such as autism and schizophrenia. Identification and functional characterization of the genetic causes of this disorder will enhance our knowledge of its neurobiology and revolutionise the drug treatment of the disorder.