A contractile cochlear frame - a possible new mechanism of sound adaptation. It is generally accepted that the rigid frame that harbours sensory structures in the hearing organs of modern higher vertebrates has only a passive supporting role. We have discovered a contractile component in the cartilaginous cochlear frame of the lizard Teratoscincus scincus and demonstrated that the tonus of the contractile tissue can be regulated. We hypothesize a new, previously unknown mechanism of slow mechani ....A contractile cochlear frame - a possible new mechanism of sound adaptation. It is generally accepted that the rigid frame that harbours sensory structures in the hearing organs of modern higher vertebrates has only a passive supporting role. We have discovered a contractile component in the cartilaginous cochlear frame of the lizard Teratoscincus scincus and demonstrated that the tonus of the contractile tissue can be regulated. We hypothesize a new, previously unknown mechanism of slow mechanical adaptation in the vertebrate hearing organ. The aim of the proposed project is to examine this hypothesis in more detail.
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Pharmacological modification of retinal and visual function and relation to control of refractive error. Myopia (short-sightedness) affects many hundreds of millions of people worldwide and can lead to blindness. Drug treatments that prevent myopia are being developed, however there is no efficient way of determining who is at risk of myopia or who will benefit from these treatments. This fundamental research project will determine the retinal and visual effects of pharmacologic agents that inhi ....Pharmacological modification of retinal and visual function and relation to control of refractive error. Myopia (short-sightedness) affects many hundreds of millions of people worldwide and can lead to blindness. Drug treatments that prevent myopia are being developed, however there is no efficient way of determining who is at risk of myopia or who will benefit from these treatments. This fundamental research project will determine the retinal and visual effects of pharmacologic agents that inhibit myopia, with the aim of determining an ocular measure that is related to myopia, which is altered by drugs that are known to slow myopia progression, and that could be used as an indication of an agent's likely effectiveness.Read moreRead less
Motion and Spatial Coding in Vision. The results of this project will have implications for the design and implementation of artificial visual systems. Completion of this project will depend upon international collaboration - forging links between a young Australian investigator and outstanding overseas scientists as well as providing excellent training opportunities. Subsequent publication of the research in top-ranking international journals will further promote Australian science abroad.
ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision system ....ARC Centre of Excellence - Vision Science. This Centre will generate important new knowledge of the performance, logic and stability of vision and visual behaviour. This knowledge will help reduce the burden of vision impairment in Australia, increasing productivity, promoting healthy ageing and reducing the community costs of visual impairment (ca. $9.85 billion in 2004). The knowledge produced will also make possible world-class innovations in robotics, leading to novel automated vision systems with applications in industry and national security. Other knowledge will develop novel diagnostic technologies, for application in health delivery.Read moreRead less
Assembly of neural circuits during development. This program aims to understand how nerve cells wire up accurately during development. Specifically, the program will determine how neuronal connections are established in the retina to produce a sensory structure essential for vision. The program will also generate innovative tools for watching in live animals, the making and breaking of connections during normal and abnormal development. Discoveries will not only significantly increase our knowle ....Assembly of neural circuits during development. This program aims to understand how nerve cells wire up accurately during development. Specifically, the program will determine how neuronal connections are established in the retina to produce a sensory structure essential for vision. The program will also generate innovative tools for watching in live animals, the making and breaking of connections during normal and abnormal development. Discoveries will not only significantly increase our knowledge base of how the nervous system develops or degenerates, but the results will provide crucial information for future studies based on genetic approaches, drug therapies and bioengineering technology to repair the injured nervous system.Read moreRead less
Neural mechanisms of attention in the honeybee and Drosophila melanogaster. By examining convergent neural mechanisms of attention in insects and comparing these mechanisms to those found in vertebrates, we may uncover basic principles of how attention operates in widely divergent systems. This type of basic scientific research could be used to provide a framework to develop better approaches for treatment for individuals with defects in attention. Such defects are symptoms of several psycholo ....Neural mechanisms of attention in the honeybee and Drosophila melanogaster. By examining convergent neural mechanisms of attention in insects and comparing these mechanisms to those found in vertebrates, we may uncover basic principles of how attention operates in widely divergent systems. This type of basic scientific research could be used to provide a framework to develop better approaches for treatment for individuals with defects in attention. Such defects are symptoms of several psychological conditions, including attention deficit disorder, autism, and schizophrenia, which have major social and economic costs in Australia. Therefore, by expanding our understanding of how attention operates at the level of neurons, we can begin to develop targeted treatments for addressing these conditions. Read moreRead less
Processing of social communication calls in primate auditory cortex. This research will advance our understanding of the brain mechanisms involved in perception of sound. This will help to understand disorders of speech and hearing following brain damage and may assist in efforts to develop better hearing aids, as well as other speech recognition technologies. In addition, we will develop a primate for studying processing of sound in the brain that will be useful in future research to develop ....Processing of social communication calls in primate auditory cortex. This research will advance our understanding of the brain mechanisms involved in perception of sound. This will help to understand disorders of speech and hearing following brain damage and may assist in efforts to develop better hearing aids, as well as other speech recognition technologies. In addition, we will develop a primate for studying processing of sound in the brain that will be useful in future research to develop improved cochlear implants.Read moreRead less
Probing cross modal interactions in the perception of object motion and self-motion. How the brain integrates information from the different senses is not yet understood. This project aims first, to uncover how the brain integrates sound and visual information when perceiving moving objects and second, to probe more complex sensory interactions between sound, vision, and our vestibular senses when perceiving self-motion. This project will expand Australia's knowledge base, strengthen collabora ....Probing cross modal interactions in the perception of object motion and self-motion. How the brain integrates information from the different senses is not yet understood. This project aims first, to uncover how the brain integrates sound and visual information when perceiving moving objects and second, to probe more complex sensory interactions between sound, vision, and our vestibular senses when perceiving self-motion. This project will expand Australia's knowledge base, strengthen collaborative ties between Australia and Japan, and provide unique training opportunities for Australian and Japanese students. Publication of research in top-ranking journals will further promote Australian science abroad. Results will lead to improvements in the design of human-machine interfaces in both industry and entertainment.Read moreRead less
Vision and remote sensing: using nature's technology to examine the health of The Great Barrier Reef and Moreton Bay. We aim to use what is known and what we will discover about animals visual systems to examine environmental health on The Great Barrier Reef and Moreton Bay. Technology and knowledge from 8 university departments, 4 industry partners, and 7 international collaborators will be combined to both learn and provide information. The innovative aspect of our approach is to examine the w ....Vision and remote sensing: using nature's technology to examine the health of The Great Barrier Reef and Moreton Bay. We aim to use what is known and what we will discover about animals visual systems to examine environmental health on The Great Barrier Reef and Moreton Bay. Technology and knowledge from 8 university departments, 4 industry partners, and 7 international collaborators will be combined to both learn and provide information. The innovative aspect of our approach is to examine the world with the eyes of birds, fish and invertebrates. Tricks animals employ to solve visual tasks will be implemented at scales of instrumentation from hand-held to remote sensing and used to address problems such as coral reef bleaching.Read moreRead less
Mechanisms of learning at the interface between perception and action. Using the latest in brain imaging and simulator technology, this project will advance understanding of how experience shapes the visual centres of our brain. It will also support partnerships with construction, mining and health services by developing real and virtual machine interfaces and tools to enhance the outcome of simulator-based training.