Resolving multi-sensory conflict as we age: audio-visual integration and the role of normal and abnormal sensory decline. Australia has an ageing population. Even the healthiest older individuals undergo some deterioration of vision and hearing, however, these senses are almost invariably studied in isolation. The real world is multisensory. This project will enhance our knowledge of how ageing impacts on the interpretation of visual and auditory information regarding the timing and location of ....Resolving multi-sensory conflict as we age: audio-visual integration and the role of normal and abnormal sensory decline. Australia has an ageing population. Even the healthiest older individuals undergo some deterioration of vision and hearing, however, these senses are almost invariably studied in isolation. The real world is multisensory. This project will enhance our knowledge of how ageing impacts on the interpretation of visual and auditory information regarding the timing and location of objects; essential precursors to many real world tasks, for example: driving, interpreting speech, and hazard avoidance. This knowledge is essential for the optimisation of audio-visual environments for the elderly, and for the development of tools to improve performance in the presence of sensory decline due to age-related eye disease.Read moreRead less
Understanding the consequences of normal ageing on visual form perception. Australia has an ageing population. Within the elderly, vision is a key sense that contributes significantly to the maintenance of independence, mobility and participation in society. This project will enhance our knowledge of the impact of ageing on vision. The research findings are important to a variety of disciplines involved in planning for our ageing population; for example: the design of living/working spaces for t ....Understanding the consequences of normal ageing on visual form perception. Australia has an ageing population. Within the elderly, vision is a key sense that contributes significantly to the maintenance of independence, mobility and participation in society. This project will enhance our knowledge of the impact of ageing on vision. The research findings are important to a variety of disciplines involved in planning for our ageing population; for example: the design of living/working spaces for the elderly, information technology, and the design of technology to assist with independent living. This project will train students in visual psychophysics, continuing the strong international reputation and output of Australian scientists in this discipline.Read moreRead less
New, Efficient Tests That Map Both Central and Peripheral Vision. This project seeks to develop a new, combined approach for quantifying both central and peripheral vision with a single test. Current methods for testing far peripheral vision are not efficient and not fully automated. Yet peripheral vision is important for tasks involving navigation and hazard avoidance such as driving. The project intends to invent and test new approaches to sampling and measuring the spatial extent of vision. T ....New, Efficient Tests That Map Both Central and Peripheral Vision. This project seeks to develop a new, combined approach for quantifying both central and peripheral vision with a single test. Current methods for testing far peripheral vision are not efficient and not fully automated. Yet peripheral vision is important for tasks involving navigation and hazard avoidance such as driving. The project intends to invent and test new approaches to sampling and measuring the spatial extent of vision. The anticipated algorithms will be more accurate and efficient than current tests, will be suitable for older adults, and will enable ready assessment of vision for occupational tasks.Read moreRead less
The effect of cochlear implants on cognitive decline in ageing Australians. This project aims to investigate the impact of cochlear implants on cognitive function in elderly people with deafness. Deafness has been found to be independently associated with a 30–40 per cent accelerated rate of cognitive decline in elderly adults. There is currently no effective treatment for cognitive decline. The intended outcomes of this observational study will help us to understand the biological process of co ....The effect of cochlear implants on cognitive decline in ageing Australians. This project aims to investigate the impact of cochlear implants on cognitive function in elderly people with deafness. Deafness has been found to be independently associated with a 30–40 per cent accelerated rate of cognitive decline in elderly adults. There is currently no effective treatment for cognitive decline. The intended outcomes of this observational study will help us to understand the biological process of cognitive decline, whether hearing loss is causal, and whether the process can be altered. These findings should be applicable to all individuals with hearing loss. If cochlear implants delay cognitive decline, this would significantly affect policy, quality of life for the elderly, and the cost to society.Read moreRead less
Wiring the retina for human vision - a single-cell behavioural approach. This project aims to combine optical and behavioural methods to explore how colour information is channelled from individual cone photoreceptors through the living human retina, to the brain. By non-invasively stimulating either a single cell or specific arrangements of cells, the project aims to contribute fundamental knowledge about how the retina is wired to inform our exquisite sense of colour and spatial vision. This u ....Wiring the retina for human vision - a single-cell behavioural approach. This project aims to combine optical and behavioural methods to explore how colour information is channelled from individual cone photoreceptors through the living human retina, to the brain. By non-invasively stimulating either a single cell or specific arrangements of cells, the project aims to contribute fundamental knowledge about how the retina is wired to inform our exquisite sense of colour and spatial vision. This understanding has consequences across a range of disciplines, including artificial vision systems such as driverless cars, retinal disease, and the processing of information through neuronal connections in general.Read moreRead less
Motion and Spatial Coding in Vision. The results of this project will have implications for the design and implementation of artificial visual systems. Completion of this project will depend upon international collaboration - forging links between a young Australian investigator and outstanding overseas scientists as well as providing excellent training opportunities. Subsequent publication of the research in top-ranking international journals will further promote Australian science abroad.
Phenotypic differences in behaviour, brain function and structure of genetically dissimilar forms of intellectual disability. How is the brain of someone with intellectual disability different from that of a normal person? Are behavioural phenotypes such as intellectual disability more related to similarities in brain structure and function than to the genotypic anomaly? This project will use neuroscience techniques of psychophysics, electrophysiology and fMRI to probe these questions. The ben ....Phenotypic differences in behaviour, brain function and structure of genetically dissimilar forms of intellectual disability. How is the brain of someone with intellectual disability different from that of a normal person? Are behavioural phenotypes such as intellectual disability more related to similarities in brain structure and function than to the genotypic anomaly? This project will use neuroscience techniques of psychophysics, electrophysiology and fMRI to probe these questions. The benefit of this project is that cortical flattening fMRI techniques together with new and efficient stimulus paradigms will result in a functional landmark mapping tool capable of application to many other brain genotype-phenotype questions. Also, the functional brain basis of intellectual disability will be further revealed.Read moreRead less
How the brain produces speech. Speech production is a fundamental ability that enables human interaction through language. Brain injuries impair this ability, with profound negative consequences for the individual and their immediate family and friends. This project will increase our understanding of the brain mechanisms involved in producing speech by using state-of-the-art brain imaging techniques. The findings will inform future clinical research and improve the advice given to clinicians, pa ....How the brain produces speech. Speech production is a fundamental ability that enables human interaction through language. Brain injuries impair this ability, with profound negative consequences for the individual and their immediate family and friends. This project will increase our understanding of the brain mechanisms involved in producing speech by using state-of-the-art brain imaging techniques. The findings will inform future clinical research and improve the advice given to clinicians, patients and the broader community about the nature of language production and its impairments and ultimately the treatment of speech disorders.Read moreRead less
Enhancing Language Learning in Ageing With Exercise. This project aims to determine if exercise improves language learning and consolidation in ageing. There is now compelling evidence for the benefits of exercise on cognition in older adults, however, it is unclear whether exercise improves age-related language problems. The project plans to examine exercise-induced changes in brain activity and biomarkers in an innovative set of studies that seeks to identify the brain mechanisms involved. The ....Enhancing Language Learning in Ageing With Exercise. This project aims to determine if exercise improves language learning and consolidation in ageing. There is now compelling evidence for the benefits of exercise on cognition in older adults, however, it is unclear whether exercise improves age-related language problems. The project plans to examine exercise-induced changes in brain activity and biomarkers in an innovative set of studies that seeks to identify the brain mechanisms involved. The findings are expected to contribute to theories of word learning and cognitive ageing and should advance our understanding of how exercise may be harnessed to optimise language and cognition. This would have practical applications in a range of populations with language and learning difficulties.Read moreRead less
Reconciling perceptual and cognitive accounts of dyslexia: The neural rate deficit hypothesis. The proposed research will form part of a co-ordinated program to understand the causes of dyslexia, a disorder that affects a large number of children and often persists into adulthood. It complements parallel efforts to elucidate the genetic basis of dyslexia, the heterogeneity and subtypes of dyslexia, and the developmental precursors to the disorder. This research will inform early intervention and ....Reconciling perceptual and cognitive accounts of dyslexia: The neural rate deficit hypothesis. The proposed research will form part of a co-ordinated program to understand the causes of dyslexia, a disorder that affects a large number of children and often persists into adulthood. It complements parallel efforts to elucidate the genetic basis of dyslexia, the heterogeneity and subtypes of dyslexia, and the developmental precursors to the disorder. This research will inform early intervention and remediation efforts and will also assist in the understanding of the normal process of reading acquisition in children.Read moreRead less