Nano-Rheology and Nano-Tribology: Atomistic Simulation of Boundary Lubrication. Manufacturing in atomic level is going to transform the efficiency level in many important applications. As molecular biology transformed medical and biological sciences,so molecular level material design and the techniques involved are going to significantly affect the engineering applications and manufacturing in coming decades. We have no doubt the benefits will flow from the project to many disciplines that are c ....Nano-Rheology and Nano-Tribology: Atomistic Simulation of Boundary Lubrication. Manufacturing in atomic level is going to transform the efficiency level in many important applications. As molecular biology transformed medical and biological sciences,so molecular level material design and the techniques involved are going to significantly affect the engineering applications and manufacturing in coming decades. We have no doubt the benefits will flow from the project to many disciplines that are critical in manufacturing and commercialisation of nano-devices. The results will position Australia in the forefront of one of the most important leading edge technologies in the world. This not only will improve Australia's research profile in the world but also will enable it to capitalize on any future commercial outcomesRead moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882357
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
A Computational Facility for Multi-scale Modelling in Bio and Nanotechnology. Bio- and nanotechnology have the potential to transform Australian industry and research, and to bring significant benefits for consumers. The scope will include materials for energy storage, medical diagnostics and cellular imaging, bioengineering, drug and gene delivery, improved foods by molecular design, novel materials for electronics, improved techniques for particle processing, and molecular sieves for filtering ....A Computational Facility for Multi-scale Modelling in Bio and Nanotechnology. Bio- and nanotechnology have the potential to transform Australian industry and research, and to bring significant benefits for consumers. The scope will include materials for energy storage, medical diagnostics and cellular imaging, bioengineering, drug and gene delivery, improved foods by molecular design, novel materials for electronics, improved techniques for particle processing, and molecular sieves for filtering/purifying water and gases. The dedicated computing facility will enable a fast interactive cycle between simulation and experiment in these areas, accelerating the pace of research and applications.Read moreRead less
Nanostrutured Magnesium-base Composites for High-density Hydrogen Storage. This project aims to develop nanocrstalline magnesium-based composites for effective hydrogen storage, overcoming two main technical barriers of current metal hydride systems: high charging/discharging temperature and slow kinetics. Nanoscale catalysts based on mesoporous carbons and metal nanoparticles will be introduced into the magnesium to increase storage capacity and increase the rate at low temperatures. Fundament ....Nanostrutured Magnesium-base Composites for High-density Hydrogen Storage. This project aims to develop nanocrstalline magnesium-based composites for effective hydrogen storage, overcoming two main technical barriers of current metal hydride systems: high charging/discharging temperature and slow kinetics. Nanoscale catalysts based on mesoporous carbons and metal nanoparticles will be introduced into the magnesium to increase storage capacity and increase the rate at low temperatures. Fundamental understanding on the effects of catalysts, and adsorption and desorption mechanisms will be obtained to optimise the composite materials. This project will lead to effective and practical technology for hydrogen storage that will meet the target of commercial fuel cell vehicles.Read moreRead less
NANO-SCALE CATALYST SYSTEMS FOR HYDROGEN GENERATION FOR FUEL CELLS. The project aims to develop nano-scale catalyst materials for micro-channel fuel processing systems. Micro-channel reactors have the benefits over conventional technology of being more compact and potential for much lower costs. This will assist in the development of hydrogen generation systems for fuel cells, as well as other chemical processing applications such as gas-to-liquids technology. The technology has the potential t ....NANO-SCALE CATALYST SYSTEMS FOR HYDROGEN GENERATION FOR FUEL CELLS. The project aims to develop nano-scale catalyst materials for micro-channel fuel processing systems. Micro-channel reactors have the benefits over conventional technology of being more compact and potential for much lower costs. This will assist in the development of hydrogen generation systems for fuel cells, as well as other chemical processing applications such as gas-to-liquids technology. The technology has the potential to generate significant IP in an evolving multi-billion dollar fuel cell industry. Support from Ceramic Fuel Cells Ltd. and the Gas Technology Institute will ensure that the work has an international as well as national perspective, and a route to exploitation.Read moreRead less
Magnetically controlled drug release from tissue scaffolds for the treatment of acute burns. Severe skin burns are frequently associated with functionally disabling scarring and the risk of death. New magnetically activated wound seals for the treatment of acute burns will be developed that reduce the need for frequent painful dressing changes and hence facilitate rapid healing with a significantly reduced chance of scarring.
Nanoparticles to combat cellular dysfunction. This project aims to design, synthesise and characterise nanoparticles that can mediate the adverse effects of reactive oxygen species. The project expects to develop nanoparticles with tailored chemical functionality to modulate the concentration of reactive oxygen species and develop a platform technology for addressing conditions where reactive species are overproduced. The project will research how nanoparticles’ physicochemical properties affect ....Nanoparticles to combat cellular dysfunction. This project aims to design, synthesise and characterise nanoparticles that can mediate the adverse effects of reactive oxygen species. The project expects to develop nanoparticles with tailored chemical functionality to modulate the concentration of reactive oxygen species and develop a platform technology for addressing conditions where reactive species are overproduced. The project will research how nanoparticles’ physicochemical properties affect their activity, and how they affect cellular function, tissue morphology and particle transport in a biological milieu. The project is expected to benefit the advanced manufacturing, veterinary and medical sectors and could lead to new chemotherapeutics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989567
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
State of the Art Surface Characterisation Facility for the Sydney Basin. Many of the grand challenges of our time, including finding alternative sources of energy, maximizing our current supply of natural resources, identifying and treating pollution in general, and in water in particular, and developing therapies and biomaterials that enable the personalisation of therapies to each individual are being solved using developments in the molecular sciences. Pivotal to the success of such research ....State of the Art Surface Characterisation Facility for the Sydney Basin. Many of the grand challenges of our time, including finding alternative sources of energy, maximizing our current supply of natural resources, identifying and treating pollution in general, and in water in particular, and developing therapies and biomaterials that enable the personalisation of therapies to each individual are being solved using developments in the molecular sciences. Pivotal to the success of such research is to understand materials and surfaces at the molecular level. The request is to purchase surface analysis instrumentation which will dramatically enhance the ability of scientists around Australia understand how to develop solutions to these grand challenges.Read moreRead less
New Strategies for Monitoring DNA-Anticancer Drug Interactions. The highly successful cisplatin works by binding to DNA and partially unwinding or bending the DNA. As a consequence of the success if cisplatin, alternative anticancer drugs are being developed with reduced side effects for patients. One of the bottom necks in the development of alternative drugs is rapid screening of the efficacy on new leads. The proposed research will develop new technologies for monitoring DNA-drug binding, ....New Strategies for Monitoring DNA-Anticancer Drug Interactions. The highly successful cisplatin works by binding to DNA and partially unwinding or bending the DNA. As a consequence of the success if cisplatin, alternative anticancer drugs are being developed with reduced side effects for patients. One of the bottom necks in the development of alternative drugs is rapid screening of the efficacy on new leads. The proposed research will develop new technologies for monitoring DNA-drug binding, DNA damage and DNA repair using novel DNA biosensors. the novelty of the biosensor technology will be to use the modulation of charge transfer through DNA as a method for determining the structural changes that occur in DNA due to these events occurring.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100488
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Cellular dynamics of nanoengineered particles. Nanotechnology has the capacity to drive a new wave of biological innovation through engineering materials at the nanoscale. This project will advance understanding of how nanoengineered materials interact with biological systems to enable the development of nanomaterials for future translational research.
Engineering layered double hydroxide nanoparticles toward an efficient targeted clinical delivery system. This project will develop a more effective drug delivery system using clay nanoparticles and biofriendly serum proteins. Outcomes from this project will provide a tremendous opportunity for potent therapies of cancers, vasculature and neuronal diseases, and place Australia at the forefront of nanotechnology drug delivery research.