Centre For Clinical Research Excellence In Aboriginal Health: Sexually Transmitted And Bloodborne Viral Infections
Funder
National Health and Medical Research Council
Funding Amount
$2,553,623.00
Summary
This proposed new CCRE will bring together the leading Australian institution dedicated to clinical research on sexually transmitted and blood borne viral infections, and the peak organisation for Aboriginal Community Controlled Health Services. Working with nominated Aboriginal community controlled health services, the Centre will conduct innovative research that will identify new approaches to diagnosing and managing these infections while at the same time developing improved clinical guidelin ....This proposed new CCRE will bring together the leading Australian institution dedicated to clinical research on sexually transmitted and blood borne viral infections, and the peak organisation for Aboriginal Community Controlled Health Services. Working with nominated Aboriginal community controlled health services, the Centre will conduct innovative research that will identify new approaches to diagnosing and managing these infections while at the same time developing improved clinical guidelines and research capacity within the sector.Read moreRead less
Deadly Liver Mob: Engaging Aboriginal People In Viral Hepatitis, HIV And Sexual Health Services
Funder
National Health and Medical Research Council
Funding Amount
$848,441.00
Summary
Rates of blood-borne viruses and sexually transmissible infections are high among the Aboriginal and Torres Strait Islander population. A local initiative in western Sydney has trialed a new approach to engagement and care of Aboriginal people. We will implement this approach in services across NSW and evaluate its effectiveness as a sustainable and acceptable model for engaging Aboriginal people in care and develop an implementation plan for future roll-out to other services.
Imaging The Hepatitis C Virus Life Cycle In Real-time
Funder
National Health and Medical Research Council
Funding Amount
$477,504.00
Summary
Hepatitis C virus (HCV) is a serious viral pathogen that causes significant liver disease. This proposal plans to examine how two proteins from the HCV, core and NS5A, interact with host proteins and pathways to facilitate viral replication and release of HCV; two processes that are poorly understood. Specifically we will tag viral proteins to allow us to investigate the HCV life cycle in living cells and determine the role of core and NS5A in facilitating HCV replication. This proposal may unco ....Hepatitis C virus (HCV) is a serious viral pathogen that causes significant liver disease. This proposal plans to examine how two proteins from the HCV, core and NS5A, interact with host proteins and pathways to facilitate viral replication and release of HCV; two processes that are poorly understood. Specifically we will tag viral proteins to allow us to investigate the HCV life cycle in living cells and determine the role of core and NS5A in facilitating HCV replication. This proposal may uncover novel therapeutic strategies to combat HCV.Read moreRead less