Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to unde ....ARC Centre of Excellence for Nanoscale BioPhotonics. The CNBP brings together physicists, chemists and biologists focused on a grand challenge controlling nanoscale interactions between light and matter to probe the complex and dynamic nanoenvironments within living organisms. The emerging convergence of nanoscience and photonics offers the opportunity of using light to interrogate nanoscale domains, providing unprecedentedly localised measurements. This will allow biological scientists to understand how single cells react to and communicate with their surroundings. This science will underpin a new generation of devices capable of probing the response of cells within individuals to environmental conditions or treatment, creating innovative and powerful new sensing platforms.Read moreRead less
ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reac ....ARC Centre of Excellence in Quantum Biotechnology. ARC Centre of Excellence in Quantum Biotechnology. The ARC Centre of Excellence in Quantum Biotechnology aims to develop paradigm-shifting quantum technologies to observe biological processes and transform our understanding of life. It seeks to create technologies that go far beyond what is possible today, from portable brain imagers to super-fast single protein sensors, and to use them to unravel key problems including how enzymes catalyse reactions and how higher brain function emerges from networks of neurons. By building a diverse, multidisciplinary, and industry-engaged ecosystem, the Centre means to develop our future leaders at the interface of quantum science and biology and drive Australian innovation across manufacturing, energy, agriculture, health, and national security.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100002
Funder
Australian Research Council
Funding Amount
$3,000,000.00
Summary
Australian Partnership in Advanced LIGO+: continuation. The aim of this project is, in collaboration with the USA and UK, to complete the installation and commissioning of the Advanced LIGO+ facilities in the USA in order to bring them to design sensitivity. These facilities expect to increase the event rate of gravitational wave signals by a factor of 125. This should lead to daily detections and the observation of new sources of gravitational waves. Given that only 5% of the universe is detect ....Australian Partnership in Advanced LIGO+: continuation. The aim of this project is, in collaboration with the USA and UK, to complete the installation and commissioning of the Advanced LIGO+ facilities in the USA in order to bring them to design sensitivity. These facilities expect to increase the event rate of gravitational wave signals by a factor of 125. This should lead to daily detections and the observation of new sources of gravitational waves. Given that only 5% of the universe is detectable by telescopes, the impact of gravitational wave detections on our understanding of the universe is inestimable. Australian partnership intends to enable our physicists and astronomers to be at the vanguard of this brand new field and inspire a new generation to study the physical sciences.Read moreRead less
ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting- ....ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting-edge technologies. The Centre will exploit the unique geographical location of the first underground physics lab in the Southern Hemisphere. The ultra-sensitive detectors and ultra-low radiation techniques will translate into a broad range of industrial applications and train a new generation of scientists.Read moreRead less
Hierarchically porous polymer monoliths for separation science. Understanding the molecular composition of biomarkers involved in cell-cell communication and the fate of nanoparticles in the environment is critical to improve our understanding of diseases and environmental processes. This project will develop a new approach for the design of separation media that will greatly improve the efficiency of techniques used to analyse these complex samples. The separation media will consist of a polyme ....Hierarchically porous polymer monoliths for separation science. Understanding the molecular composition of biomarkers involved in cell-cell communication and the fate of nanoparticles in the environment is critical to improve our understanding of diseases and environmental processes. This project will develop a new approach for the design of separation media that will greatly improve the efficiency of techniques used to analyse these complex samples. The separation media will consist of a polymer containing large flow-through pores as well as well-defined mesopores. This dual porous skeleton will allow for the size-based separation of biomarkers and nanoparticles. The new separation media will enable the development of new technologies with applications in areas such medicine and environmental science.Read moreRead less
Levitated Quantum Optomechanics with Trapped, Rotating Microparticles. This project will develop techniques for trapping, rotating and cooling microscopic particles in vacuum for exquisitely accurate studies of sensors and of fundamental physics at the classical-quantum interface - namely quantum vacuum friction. It will result in the establishment of an internationally recognised activity in rotational levitated optomechanics and expand Australia's presence in the field of quantum photonics. It ....Levitated Quantum Optomechanics with Trapped, Rotating Microparticles. This project will develop techniques for trapping, rotating and cooling microscopic particles in vacuum for exquisitely accurate studies of sensors and of fundamental physics at the classical-quantum interface - namely quantum vacuum friction. It will result in the establishment of an internationally recognised activity in rotational levitated optomechanics and expand Australia's presence in the field of quantum photonics. It has the potential for commercial benefit in areas including photonics, sensors and advanced manufacturingRead moreRead less
Australian Laureate Fellowships - Grant ID: FL210100099
Funder
Australian Research Council
Funding Amount
$3,401,828.00
Summary
The Intelligent Microscope - novel optical imaging at depth. While optical methods for imaging are used extensively, achieving wide-field imaging through scattering media with high resolution and depth is a major challenge, due mainly to the limited penetration depth of light. This proposal aims to transform wide-field optical imaging through a new ‘intelligent’ microscopy able to capture 3D volumetric images. Innovations in shaping light in both space and time will be combined in a holistic wa ....The Intelligent Microscope - novel optical imaging at depth. While optical methods for imaging are used extensively, achieving wide-field imaging through scattering media with high resolution and depth is a major challenge, due mainly to the limited penetration depth of light. This proposal aims to transform wide-field optical imaging through a new ‘intelligent’ microscopy able to capture 3D volumetric images. Innovations in shaping light in both space and time will be combined in a holistic way with computational analysis to extract images from deep within the sample at extraordinary levels of detail. Major benefits of the research range from next-generation tools for enhanced discovery of biological and physical materials, to new Australian start-ups for new imaging and microscopy devices.Read moreRead less
High shear fluid flow driving carbon foundry for advanced manufacturing. This project aims to develop versatile continuous flow thin film microfluidic device technology for harnessing contact electrification generated by sub-micron high shear flows in fabricating novel and high-performance nano-carbons for which current methods are ineffective or impossible. This project expects to generate new knowledge on complex vortex fluid fields, their intricate interactions with external electric and magn ....High shear fluid flow driving carbon foundry for advanced manufacturing. This project aims to develop versatile continuous flow thin film microfluidic device technology for harnessing contact electrification generated by sub-micron high shear flows in fabricating novel and high-performance nano-carbons for which current methods are ineffective or impossible. This project expects to generate new knowledge on complex vortex fluid fields, their intricate interactions with external electric and magnetic fields and carbon nanostructure formation. Expected outcomes for this project include exquisite control on reforming nanocarbon with tuneable properties and unprecedented hetero-structures. This should provide significant benefits, such as in generating new processes and products for advanced manufacturing. Read moreRead less
Enhanced sensitivity of electrospray ionization mass spectrometry. Enhanced sensitivity of electrospray ionization mass spectrometry. This project aims to enhance the sensitivity of nano-electrospray ionization mass spectrometry (nanoESI-MS) by an order of magnitude by simultaneously overcoming the two interdependent limitations in ion generation and transmission efficiency. This project will design glass capillaries and tubes with complex structures to enable both multiplexing ion generation fr ....Enhanced sensitivity of electrospray ionization mass spectrometry. Enhanced sensitivity of electrospray ionization mass spectrometry. This project aims to enhance the sensitivity of nano-electrospray ionization mass spectrometry (nanoESI-MS) by an order of magnitude by simultaneously overcoming the two interdependent limitations in ion generation and transmission efficiency. This project will design glass capillaries and tubes with complex structures to enable both multiplexing ion generation from a single capillary and geometrically matching the bore of the tube collecting the emitted ion plume. NanoESI-MS has become an indispensable analytical tool for proteomics and synthetic chemistry. The significant enhancement of nanoESI-MS sensitivity in this project is expected to accelerate progress in disease research, biomarker discovery and drug development.Read moreRead less