Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will ena ....Developing feasible in situ control of mange disease in wombats. Our goal is the development of feasible in situ control of sarcoptic mange in wombat populations. Globally important, the Sarcoptes scabiei mite infects >100 mammal species and is among the 50 most common human diseases, causing health, welfare and population impacts. This infection is treatable, and we will test a new treatment (fluralaner), develop new models to guide management, and conduct replicated field trials. This will enable science-based guidelines, advancing disease control, local eradication, and regulatory approval for wombats. Our research framework is adaptable to other mange-impacted species, and advance methods and theory for control of treatable disease in wildlife.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre wi ....ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre will accelerate technologies to transfer successful networks into crops and build legal frameworks to secure this knowledge. With a uniquely multidisciplinary team, the Centre will deliver new strategies to address the problems of food security and climate change, establishing Australia as a global leader in these areas.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100201
Funder
Australian Research Council
Funding Amount
$530,000.00
Summary
A major upgrade to the Australia Telescope Compact Array. This project aims to upgrade the $150m CSIRO Australia Telescope Compact Array ("the telescope"), by replacing the signal processing electronics and doubling the bandwidth. This will significantly enhance the performance of the telescope, enabling more ambitious science by the 450 researchers and students who use it each year. For example, it will enable the telescope to study radio counterparts to Gravitational Wave sources, and it will ....A major upgrade to the Australia Telescope Compact Array. This project aims to upgrade the $150m CSIRO Australia Telescope Compact Array ("the telescope"), by replacing the signal processing electronics and doubling the bandwidth. This will significantly enhance the performance of the telescope, enabling more ambitious science by the 450 researchers and students who use it each year. For example, it will enable the telescope to study radio counterparts to Gravitational Wave sources, and it will enable it to make detailed observations of initial discoveries made with the Australian Square Kilometre Array Pathfinder and other Australian telescopes. In short, it will enable Australian researchers to do more ambitious research, and make more discoveries, across broad areas of astrophysics.Read moreRead less
Understanding the mechanisms underpinning complex sociality. This project aims to investigate the mechanisms underlying the formation of complex social systems in vertebrates. Our understanding of these mechanisms is strongly biased towards a few model systems. We have identified a novel Australian model system with a wide range of sociality for this purpose. This project expects to generate new knowledge on how the social environment interacts with the brain during social organisation. Expected ....Understanding the mechanisms underpinning complex sociality. This project aims to investigate the mechanisms underlying the formation of complex social systems in vertebrates. Our understanding of these mechanisms is strongly biased towards a few model systems. We have identified a novel Australian model system with a wide range of sociality for this purpose. This project expects to generate new knowledge on how the social environment interacts with the brain during social organisation. Expected outcomes include the refinement of social theory and capacity building via international collaboration and postgraduate training. This work will provide significant benefits by increasing our understanding of how the brain and social environment interact to moderate aggression and enhance social associations.Read moreRead less
General relativistic light propagation effects: new insight into cosmic voids, dark matter, dark energy, and Einstein's theory of gravity. This project aims to be the first to develop new methods which will allow accurate study of light propagation effects. These methods remove the “noise” (light propagation effects) from observational data, resulting in unprecedented accuracy of the analyses and new insight into properties of dark energy. At the same time these methods use the “noise” as the ac ....General relativistic light propagation effects: new insight into cosmic voids, dark matter, dark energy, and Einstein's theory of gravity. This project aims to be the first to develop new methods which will allow accurate study of light propagation effects. These methods remove the “noise” (light propagation effects) from observational data, resulting in unprecedented accuracy of the analyses and new insight into properties of dark energy. At the same time these methods use the “noise” as the actual signal to measure properties of the Universe, especially the mass distribution inside cosmic voids (places in the Universe avoided by galaxies), which will solve the problem of dark matter distribution inside cosmic voids. The project aims to use light propagation effects to test Einstein's theory of gravity at cosmological scales.Read moreRead less
Carbon in - carbon out: can carbon inputs keep up with losses in peatland? This project aims to quantify the current and predict the future carbon balance of a high altitude, carbon-dense ecosystem, namely sub-alpine grassy peatland, by measuring how environmental variables including experimental warming control the fluxes of carbon and water into and out of the system. In this way, this project will produce new knowledge on the susceptibility of high-altitude peaty soils to climate change. Expe ....Carbon in - carbon out: can carbon inputs keep up with losses in peatland? This project aims to quantify the current and predict the future carbon balance of a high altitude, carbon-dense ecosystem, namely sub-alpine grassy peatland, by measuring how environmental variables including experimental warming control the fluxes of carbon and water into and out of the system. In this way, this project will produce new knowledge on the susceptibility of high-altitude peaty soils to climate change. Expected outcomes include an enhanced ability to predict future carbon accumulation rates and the resilience of the vital water-storage and filtration services provided by these systems. This project will enhance outputs from new infrastructure and assist planning for future flood and drought management across SE Australia.Read moreRead less
Micro-electrofluidic platforms for monitoring 3D human biological models. The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability t ....Micro-electrofluidic platforms for monitoring 3D human biological models. The ability to study living cells and human biological models (cell cultures) delivers greater understanding of basic biological function and response to applied (bio)chemical stimuli. Creating the physical environments to sustain biological models, and mimic natural conditions and fluidic pathways, is immensely challenging, yet essential to deliver meaningful observational data. This project will deliver this capability through the convergence of expertise and innovation in analytical chemistry, materials science and cellular biology, ultilising the latest technology and understanding of 3D micro/electrofluidics, to enable the study and stimulation of advanced biological models, sustained within precisely controlled 3D micro-environments.Read moreRead less
Changes in the ocean's biological pump: innovative models and diagnostics. This Project aims to quantify how the ocean’s biological pump, which exports newly formed organic matter into the ocean interior, responds to environmental change. The biological pump is a key control on the global carbon and oxygen cycles, and hence on the viability of marine life. New, efficient numerical models will be developed and analysed with highly innovative mathematical methods. Expected outcomes are optimised .... Changes in the ocean's biological pump: innovative models and diagnostics. This Project aims to quantify how the ocean’s biological pump, which exports newly formed organic matter into the ocean interior, responds to environmental change. The biological pump is a key control on the global carbon and oxygen cycles, and hence on the viability of marine life. New, efficient numerical models will be developed and analysed with highly innovative mathematical methods. Expected outcomes are optimised predictive models and a new understanding of the possible future evolutions of the ocean carbon cycle, acidification, and oxygenation. This should provide significant benefits such as predictions of future ocean health, identification of processes that are sensitive to change, and strategies for marine resource management.Read moreRead less