Intrauterine Growth Restriction And Development Of The Peripheral And Coronary Vasculature
Funder
National Health and Medical Research Council
Funding Amount
$437,176.00
Summary
There have been no studies which have investigated the extent to which fetal substrate restriction and associated fetal growth restriction alter the expression of nerve growth factors which determine the extent of sympathetic innervation of the peripheral vasculature and the interaction of changes within the peripheral and coronary vasculature which may explain the association between fetal growth restriction and the emergence of cardiovascular disease and high blood pressure in later life. Thes ....There have been no studies which have investigated the extent to which fetal substrate restriction and associated fetal growth restriction alter the expression of nerve growth factors which determine the extent of sympathetic innervation of the peripheral vasculature and the interaction of changes within the peripheral and coronary vasculature which may explain the association between fetal growth restriction and the emergence of cardiovascular disease and high blood pressure in later life. These studies ill provide new insights into the lifelong cardiovascular sequelae of a suboptimal intrauterine environment.Read moreRead less
Making Sense Of Novel Ocular Neuroimmune Interactions.
Funder
National Health and Medical Research Council
Funding Amount
$436,178.00
Summary
It is becoming clear that the interaction between corneal nerves and immune cells underpin many inflammatory conditions of the ocular surface. Despite this increased interest, very little is known about the relationship between corneal nerves and immune cells in this outermost layer of the eye. This project will investigate the relationship between corneal nerves and immune cells during health and corneal inflammation to identify therapeutic targets to treat corneal disease.