A Transmission-Blocking Vaccine To Prevent Toxoplasmosis
Funder
National Health and Medical Research Council
Funding Amount
$850,225.00
Summary
Toxoplasma gondii causes a globally important zoonotic disease. It is transmitted by cats, and finds its way into our food chain via infected meat and contaminated water. We have used a unique functional genomics pipeline to discover proteins crucial for reproduction of Toxoplasma in the cat. We will now test combinations of these proteins to immunise cats and prove that we can develop a vaccine that blocks transmission of this highly significant parasitic disease.
Centre Of Research Excellence In Infectious Diseases Modelling To Inform Public Health Policy
Funder
National Health and Medical Research Council
Funding Amount
$2,600,064.00
Summary
Infectious diseases pose a global challenge, with substantial human and economic costs. Mathematical models provide valuable frameworks to assess likely benefits of interventions to control infection spread and burden. Leveraging existing NHMRC support, we will expand modeling capability to inform infectious disease control policy in Australia and our region. Focus areas include vaccine preventable disease, respiratory viruses and emerging pathogens, supported by innovative methods development.
TSGA IPA: The Australian Aquatic Animal Health And Vaccine Centre: First Phase To Establish Atlantic Salmon Biosecure Fish Facility Capabilities And Develop Strategy For An Australian Centre Of Excellence
Funder
Fisheries Research and Development Corporation
Funding Amount
$1,694,600.00
Summary
Commercial in confidence. To know more about this project please contact FRDC. Objectives: Commercial in confidence
Production Of Antibodies Against Toxins Involved In Ciguatera Fish Poisoning
Funder
Fisheries Research and Development Corporation
Funding Amount
$87,050.00
Summary
Objectives: 1. Develop method of detection of ciguatoxin (CTX) to extract & purify sufficient CTX to service requirements of program. 2. Develop an en enzyme imunassay for measuring anti-CTX production. 3. Develop method of schedule immunisation to allow production of monoclonal antibodies
SCRC: Seafood CRC Participant Sponsorship To 2011 National Seafood Industry Leadership Program
Funder
Fisheries Research and Development Corporation
Summary
The CRC is all about capacity building within the CRC participants and the FRDC Seafood Leadership Program enables the opportunity to invest in people who are keen to show their leadership potential. Investing in Leadership, and the associated networks and cross stakeholder understanding is seen as vitally important for all sectors to be able to contribute to debate, drive change and address challenges in order to enable the Seafood CRC and the industry to reach its potential.
FRDC has obtained Board approval FRDC Board Meeting # 194, 24 November 2022) to become a member of CRC SAAFE and investment up to $1.0 million. This project is needed to manage the FRDC investment that will be comprised of investments seafood related projects. Conducting projects within CRC SAAFE will provide linkages to additional resources, expertise and knowledge sharing that will improve project outputs and foster national collaboration in addition to that currently provided by the FRDC. Th ....FRDC has obtained Board approval FRDC Board Meeting # 194, 24 November 2022) to become a member of CRC SAAFE and investment up to $1.0 million. This project is needed to manage the FRDC investment that will be comprised of investments seafood related projects. Conducting projects within CRC SAAFE will provide linkages to additional resources, expertise and knowledge sharing that will improve project outputs and foster national collaboration in addition to that currently provided by the FRDC. This will include the research and industry participants that are partners of CRC SAAFE. Objectives: 1. Best practice AMR mitigation and management in the seafood industry and the aquatic environment. 2. Improved biosecurity and animal welfare through development of vaccines to minimise use of antibiotics. Read moreRead less
Development Of Vaccines And Rapid Diagnostic Monoclonal Antibodies Against Micro-organisms Associated With Diseases Of Wild And Cultured Finfish And Shellfish
Funder
Fisheries Research and Development Corporation
Funding Amount
$166,772.00
Summary
Objectives: 1. Identification and characterisation of species-specific antigenic determinants that are heat-stable components of the lipopolysaccharide (LPS) on pathogenic gram-negative bacteria. 2. Prepare a library of species and genus-specific monoclonal antibodies against the heat-stable LPS components of pathogenic gram-negative bacteria 3. Select appropriate hybridomas, that produce high affinity monoclonal antibodies, for transfer to strategic companies 4. Complete t ....Objectives: 1. Identification and characterisation of species-specific antigenic determinants that are heat-stable components of the lipopolysaccharide (LPS) on pathogenic gram-negative bacteria. 2. Prepare a library of species and genus-specific monoclonal antibodies against the heat-stable LPS components of pathogenic gram-negative bacteria 3. Select appropriate hybridomas, that produce high affinity monoclonal antibodies, for transfer to strategic companies 4. Complete the testing of specific LPS fragments extracted from one Vibrio species to produce vaccine against all Vibrio pathogens 5. Use the same approach as in (4) to test the genus-specific protection afforded by similar LPS fragrments extracted from additional pathogens, particularly Aeromonas salmonicida 6. Develop and market commercial products for use rapid diagnoses and in research of infections of wild and cultured fish and shellfish Read moreRead less