Identification Of Molecular And Cellular Pathways Predicting Susceptibility Or Resistance To Severe Dengue Fever
Funder
National Health and Medical Research Council
Funding Amount
$761,481.00
Summary
This cooperative research project aims to undertake a comprehensive immunological and molecular analysis of individuals with mild versus severe dengue fever recruited at local hospitals in Jakarta, Indonesia. The project will uncover key processes responsible for the development of severe disease. This information will identify specific biomarkers for innovative diagnostic tools for early prediction/detection of cases that will progress to complicated dengue.
Brain Injury In The Premature Born Infant: Stem Cell Regeneration Research Network
Funder
National Health and Medical Research Council
Funding Amount
$496,587.00
Summary
This project will validate to the stage of clinical trials a human mesenchymal stem cell paradigm to prevent brain injury associated with preterm birth: encephalopathy of prematurity (EoP), which leads to lifelong disability in millions of infants every year. We will achieve this by applying our vast expertise in EoP, across 7 in vivo and 11 in vitro models of EoP, by applying cutting-edge imaging approaches and partnering with experienced patient/consumer advocacy and industry partners.