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Protecting The Gut: A Novel Therapeutic Avenue For Reducing The Damaging Consequences Of Obesity
Funder
National Health and Medical Research Council
Funding Amount
$570,205.00
Summary
Most patients with obesity develop gut dysfunction. Symptoms including constipation and diarrhoea often present before other common comorbidities like diabetes and heart disease, suggesting that early pathology in obesity may begin in the gut. This research project aims to understand the mechanisms through which gut dysfunction develops in obese mice and human patients, and test a clinically approved compound that has demonstrated gut protective properties for the first time in obesity.
Systems-based Study, Intervention, Diagnosis And Control Of Gastrointestinal Parasites
Funder
National Health and Medical Research Council
Funding Amount
$2,538,220.00
Summary
Gastrointestinal parasites cause billions of infections and hundreds of thousand of deaths globally each year. Even in developed countries, these parasites remain an important public health risk, through the cost of their control, the acute impacts of infection and their contribution to post-infectious irritable bowel syndrome and chronic fatigue. My team employs cutting-edge methods to improve their diagnosis, surveillance, treatment and control.