Imaging The Hepatitis C Virus Life Cycle In Real-time
Funder
National Health and Medical Research Council
Funding Amount
$477,504.00
Summary
Hepatitis C virus (HCV) is a serious viral pathogen that causes significant liver disease. This proposal plans to examine how two proteins from the HCV, core and NS5A, interact with host proteins and pathways to facilitate viral replication and release of HCV; two processes that are poorly understood. Specifically we will tag viral proteins to allow us to investigate the HCV life cycle in living cells and determine the role of core and NS5A in facilitating HCV replication. This proposal may unco ....Hepatitis C virus (HCV) is a serious viral pathogen that causes significant liver disease. This proposal plans to examine how two proteins from the HCV, core and NS5A, interact with host proteins and pathways to facilitate viral replication and release of HCV; two processes that are poorly understood. Specifically we will tag viral proteins to allow us to investigate the HCV life cycle in living cells and determine the role of core and NS5A in facilitating HCV replication. This proposal may uncover novel therapeutic strategies to combat HCV.Read moreRead less
Coevolution of sundew bugs and sundews. This project aims to conduct a study of insect-plant interactions to determine if insects and plants coevolve or if they diversify by other evolutionary processes. Insect-plant coevolution is a hotly contested field in evolutionary biology. In Australia, a remarkable interaction exists between carnivorous plants and a group of bugs that steal the plant’s prey. This system offers a great opportunity to test competing coevolutionary theories through a combin ....Coevolution of sundew bugs and sundews. This project aims to conduct a study of insect-plant interactions to determine if insects and plants coevolve or if they diversify by other evolutionary processes. Insect-plant coevolution is a hotly contested field in evolutionary biology. In Australia, a remarkable interaction exists between carnivorous plants and a group of bugs that steal the plant’s prey. This system offers a great opportunity to test competing coevolutionary theories through a combination of historical and ecological approaches. The project expects to showcase the evolution and uniqueness of Australia’s native biota.Read moreRead less
Assessing the Role of Political and Regulatory Risks for Foreign Investors: A Multi-Country Study of Four Industry Sectors. This project will benefit Australian enterprise engaged in investment activities in Asia by providing them with the necessary methodological and analytical systems to identify, measure and assess political and regulatory risks to their investment interests. By doing so, the project will increase the investment transparency of Asia's emerging economies and thus the ability ....Assessing the Role of Political and Regulatory Risks for Foreign Investors: A Multi-Country Study of Four Industry Sectors. This project will benefit Australian enterprise engaged in investment activities in Asia by providing them with the necessary methodological and analytical systems to identify, measure and assess political and regulatory risks to their investment interests. By doing so, the project will increase the investment transparency of Asia's emerging economies and thus the ability of Australian enterprise to operate efficiently in institutionally complex and competitive offshore environments. This will benefit Australia's economy by strengthening Australia's national economic security and the safety of Australia's national savings invested in the region.Read moreRead less
Political Risk, Institutions and Regulatory Regimes: Business, Foreign Investment and Public Administration in Asia. Rating accurately the risk environment of emerging economies has always been problematic. Insufficiently developed methodological tools and the lack of institutional and regulatory data make the process imprecise. This project overcomes this problem, developing a new industry based risk assessment system for understanding political risk to commercial activities and foreign investo ....Political Risk, Institutions and Regulatory Regimes: Business, Foreign Investment and Public Administration in Asia. Rating accurately the risk environment of emerging economies has always been problematic. Insufficiently developed methodological tools and the lack of institutional and regulatory data make the process imprecise. This project overcomes this problem, developing a new industry based risk assessment system for understanding political risk to commercial activities and foreign investors in nine of Asia's most rapidly developing economies. The study, one of the first to correlate institutional and regulatory forms to the incidence, severity and recurrence of risk, will deepen our knowledge of political and regulatory institutions in Asia and provide investors with the ability to navigate those environments successfully. Read moreRead less
Shipwrecks of the Roaring Forties: a maritime archaeological reassessment of some of Australia's earliest shipwrecks. This project will evaluate new ways of investigating the history of Europeans in the Indian Ocean by using the latest technology to evaluate seven Western Australian shipwrecks excavated over 40 years ago. The project will work with emerging technologies to study these significant sites and collections.
Moral Panics and the Law in Eighteenth-Century England. This project will reveal the origins of a phenomenon that is ubiquitous in modern western society. By doing so it will attract international attention from academic historians and sociologists. It will also contribute to Australia's reputation for producing high-quality intellectual products, and further enhance its standing as a leading centre for the study of Britain in the eighteenth century. Because of its contemporary relevance the stu ....Moral Panics and the Law in Eighteenth-Century England. This project will reveal the origins of a phenomenon that is ubiquitous in modern western society. By doing so it will attract international attention from academic historians and sociologists. It will also contribute to Australia's reputation for producing high-quality intellectual products, and further enhance its standing as a leading centre for the study of Britain in the eighteenth century. Because of its contemporary relevance the study will provide a critical perspective on modern politics, especially the perception that governments legitimise their authority by helping to constitute popular anxiety about threats to moral and personal security.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668026
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
The Australian Dictionary of Biography Online and Emerging National Information Systems: Networking Research Capability. The Australian Dictionary of Biography Online and Emerging National Information Systems Project will link the dictionary's scholarly biographical articles with the resources of national cultural institutions, making visible and available to researchers everywhere an unprecedented number of sources for the lives of historical actors and a much larger volume of contextual inform ....The Australian Dictionary of Biography Online and Emerging National Information Systems: Networking Research Capability. The Australian Dictionary of Biography Online and Emerging National Information Systems Project will link the dictionary's scholarly biographical articles with the resources of national cultural institutions, making visible and available to researchers everywhere an unprecedented number of sources for the lives of historical actors and a much larger volume of contextual information about them. Its leading-edge cultural informatics will make more efficient use of existing information infrastructure and stimulate further development. Researchers using the service will be enabled to make conceptual advances and produce new knowledge about Australian history and society.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0452798
Funder
Australian Research Council
Funding Amount
$376,066.00
Summary
The Australian Dictionary of Biography Online: A Database of National Biography Facilitating Research into Australia's History. The project will publish the sixteen existing and all future volumes of the Australian Dictionary of Biography as a freely available relational database on the Internet. The A.D.B. is a fundamental research tool and teaching resource for Australian history, and a valuable source of knowledge about ten thousand past Australians. An innovative web-publication model will ....The Australian Dictionary of Biography Online: A Database of National Biography Facilitating Research into Australia's History. The project will publish the sixteen existing and all future volumes of the Australian Dictionary of Biography as a freely available relational database on the Internet. The A.D.B. is a fundamental research tool and teaching resource for Australian history, and a valuable source of knowledge about ten thousand past Australians. An innovative web-publication model will maximise the availability and searchability of the A.D.B., enabling researchers to pose new questions that will yield novel insights into Australian history. Interoperability with other on-line resources will result in a powerful addition to the country's information infrastructure, one capable of supporting high-quality research projects.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560774
Funder
Australian Research Council
Funding Amount
$260,338.00
Summary
The Australian Dictionary of Biography Online Enhancement Project: Additional Search Capabilities and Greater Interoperability for the ADB Online. The Australian Dictionary of Biography Online Enhancement Project will augment the capabilities of the ADB Online. It will provide additional search categories and means of visualising the data in the dictionary's ten thousand biographical articles, enabling researchers to discover relationships, trends and developments, and thus to explore new them ....The Australian Dictionary of Biography Online Enhancement Project: Additional Search Capabilities and Greater Interoperability for the ADB Online. The Australian Dictionary of Biography Online Enhancement Project will augment the capabilities of the ADB Online. It will provide additional search categories and means of visualising the data in the dictionary's ten thousand biographical articles, enabling researchers to discover relationships, trends and developments, and thus to explore new themes and gain new insights into the nature of Australian history and society. The project will also develop the website's interoperability with resources provided by the National Library of Australia and other trusted institutions, making the ADB a key element in an evolving national information architecture supporting research in the humanities and social sciences.Read moreRead less
Land of the Black Stump: a history of Australias Inland Corridor, 1815-2005. This project explains the origins of key areas of current interest and concern about rural and regional Australia. It provides historical lessons that address four National Research Priority areas (sustainable water and land management, sustainable communities, technological innovation, Australia in regional and global context). The project highlights the historical importance to Australia of inland regions, industries, ....Land of the Black Stump: a history of Australias Inland Corridor, 1815-2005. This project explains the origins of key areas of current interest and concern about rural and regional Australia. It provides historical lessons that address four National Research Priority areas (sustainable water and land management, sustainable communities, technological innovation, Australia in regional and global context). The project highlights the historical importance to Australia of inland regions, industries, and communities which today are undergoing fundamental economic, technological, and social readjustments. The project identifies the relationships that bind urban and rural Australia yet problematise racial reconciliation. It brings together a national network of researchers and provides vocational training for students.Read moreRead less