Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100068
Funder
Australian Research Council
Funding Amount
$931,950.00
Summary
Australian Advanced Metabolic Signal Discovery, and Imaging Platform. This proposal aims to establish an Australian Advanced Metabolic Signal Discovery and Imaging platform. The platform consists of an ultra-high resolution gas chromatography mass spectrometer and an imaging mass spectrometry upgrade for a second existing high resolution mass spectrometer. The facility will break barriers currently limiting discovery and localisation of metabolic changes during plant and animal development under ....Australian Advanced Metabolic Signal Discovery, and Imaging Platform. This proposal aims to establish an Australian Advanced Metabolic Signal Discovery and Imaging platform. The platform consists of an ultra-high resolution gas chromatography mass spectrometer and an imaging mass spectrometry upgrade for a second existing high resolution mass spectrometer. The facility will break barriers currently limiting discovery and localisation of metabolic changes during plant and animal development under environmental stress; integral chemical signals exchanged in host-microbe interactions; and volatile signatures linked to ecosystem health and developmental anomalies in animals. Results will inform innovative strategies to enhance biological adaptation, climate resilience and plant, animal, and ecosystem health.Read moreRead less
Does coevolution drive speciation? This project aims to connect micro-evolutionary processes with macro-evolutionary patterns to test the extent to which tightly coupled co-evolutionary interactions between species drive evolutionary diversification. The project will use techniques including the most recent phylogenetic modelling methods, field experiments and molecular genetics. Expected outcomes include advancing understanding of the mechanisms that generate biodiversity and developing new tec ....Does coevolution drive speciation? This project aims to connect micro-evolutionary processes with macro-evolutionary patterns to test the extent to which tightly coupled co-evolutionary interactions between species drive evolutionary diversification. The project will use techniques including the most recent phylogenetic modelling methods, field experiments and molecular genetics. Expected outcomes include advancing understanding of the mechanisms that generate biodiversity and developing new techniques for acquisition of DNA from museum specimens. The project is expected to provide significant benefits, such as insights into the processes that promote new species in nature.Read moreRead less
Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites ....Targeting the host lipid environment to disrupt malaria transmission. This project aims to characterise host molecules (in particular lipids) that are crucial for the transition of malaria parasites from one host to another. Malaria parasites encounter different environments upon their transition from human to the mosquito host. This project expects to generate new knowledge on physiological changes that are triggered by particular differences in micronutrient abundance that allow the parasites to survive in the new host. Anticipated outcomes include the identification of new intervention strategies and improved transmission model systems for vector-borne diseases. This gained knowledge could provide benefits to future biomedical applications by informing diagnostics or treatment of lipid associated diseases.Read moreRead less
Linking individual traits, the gut microbiome and parasite load in wildlife. This project aims to apply principles of community ecology to the gut microbiome of an urban exploiter – the common brushtail possum - to reveal how animal traits influence individual variation in the load of gut parasites that cause disease in both humans and wildlife. By combining assays defining the behavioural and physiological states of individuals with sophisticated analyses of their gut microbiome, our project wi ....Linking individual traits, the gut microbiome and parasite load in wildlife. This project aims to apply principles of community ecology to the gut microbiome of an urban exploiter – the common brushtail possum - to reveal how animal traits influence individual variation in the load of gut parasites that cause disease in both humans and wildlife. By combining assays defining the behavioural and physiological states of individuals with sophisticated analyses of their gut microbiome, our project will provide a new, yet crucial, perspective on how and why diseases spread. Our discoveries will help understand and manage the burden of infectious diseases from parasites in and beyond our cities and across the human-wildlife interface; essential for improving human and wildlife health in an increasingly urbanised Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100530
Funder
Australian Research Council
Funding Amount
$456,802.00
Summary
Neanderthal hunting ability and the extinction of archaic humans. This project aims to investigate a critical factor in explaining Neanderthals extinction: their hunting abilities. The research expects to generate new knowledge of archaic humans behaviour using an innovative approach combining traditional archaeological analytical methods with ground-breaking biomolecular techniques. Expected outcomes of this project include the development of new knowledge in human evolutionary history and impr ....Neanderthal hunting ability and the extinction of archaic humans. This project aims to investigate a critical factor in explaining Neanderthals extinction: their hunting abilities. The research expects to generate new knowledge of archaic humans behaviour using an innovative approach combining traditional archaeological analytical methods with ground-breaking biomolecular techniques. Expected outcomes of this project include the development of new knowledge in human evolutionary history and improved techniques to understand past human extinction events. This should provide significant benefits for Australia to become a primary power in studying human past and deep history, while enhancing capacity by becoming the first country in the Southern Hemisphere to implement ancient protein studies in archaeology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101125
Funder
Australian Research Council
Funding Amount
$365,158.00
Summary
Australindia: An environmental history of Australia, India and Empire. This project intends to examine the trajectory of environmental ideas and practices between India and Australia between 1788 and 1901. At this time, India and the Australian colonies served as important laboratories for environmental ideas and practices. Examining colonial Australia in terms of these environmental connections may broaden perspectives on Australian history and allow us to reassess the development of colonial u ....Australindia: An environmental history of Australia, India and Empire. This project intends to examine the trajectory of environmental ideas and practices between India and Australia between 1788 and 1901. At this time, India and the Australian colonies served as important laboratories for environmental ideas and practices. Examining colonial Australia in terms of these environmental connections may broaden perspectives on Australian history and allow us to reassess the development of colonial understandings of the Australian environment. The project aims to examine how people have understood and adapted to changing natural and human systems and to illuminate the ways in which the Australian environment continues to bear the legacies of empire.Read moreRead less
Challenging colonialism: Australians who helped us embrace human equality. This project aims to investigate how ten influential Australian thinkers, writers and activists helped the nation to embrace human equality in the mid-twentieth century, by tracing how challenges to colonialism and racial inequality circulated. It expects to produce new knowledge about decolonisation in a settler-state and is methodologically innovative in using group biography to follow how ideas spread outwards via netw ....Challenging colonialism: Australians who helped us embrace human equality. This project aims to investigate how ten influential Australian thinkers, writers and activists helped the nation to embrace human equality in the mid-twentieth century, by tracing how challenges to colonialism and racial inequality circulated. It expects to produce new knowledge about decolonisation in a settler-state and is methodologically innovative in using group biography to follow how ideas spread outwards via networks. Expected outcomes include developed understanding of how activists and groups successfully explained human rights and equality to mainstream Australia. Benefits should include new insight into how ideas of equality eroded cultural acceptance of White Australia and Australians reconceptualised their society as diverse.Read moreRead less
The Politics of Guilt in Asia: the Afterlife of Japanese War Crimes. This project aims to investigate the perception of Japan’s continuing guilt for atrocities committed during the Second World War. Until the 1970s, it was widely believed that Japan had resolved its guilt by accepting punishment, paying recompense and apologising, and could move on. The project expects to generate new knowledge about the process by which the idea of Japan’s guilt was revived to become a major issue in East Asian ....The Politics of Guilt in Asia: the Afterlife of Japanese War Crimes. This project aims to investigate the perception of Japan’s continuing guilt for atrocities committed during the Second World War. Until the 1970s, it was widely believed that Japan had resolved its guilt by accepting punishment, paying recompense and apologising, and could move on. The project expects to generate new knowledge about the process by which the idea of Japan’s guilt was revived to become a major issue in East Asian and world affairs. Expected outcomes include enhanced understanding of how historical grievance is constructed and why it has come to be considered always open to review. Anticipated benefits include a greater understanding of the changing ways in which historical grievance is used, both politically and ethically.Read moreRead less
Living with Smallpox in Early Modern Britain (c.1580–1780 CE). This project aims to examine how people in the past made sense of an acute infectious disease, including its long-term effects on individuals and their communities. Using traditional techniques and digital tools, it anticipates reconstructing how the experiences of the majority – who survived – were shaped by their socio-cultural circumstances, and tracing how those experiences changed over time, particularly in relation to advances ....Living with Smallpox in Early Modern Britain (c.1580–1780 CE). This project aims to examine how people in the past made sense of an acute infectious disease, including its long-term effects on individuals and their communities. Using traditional techniques and digital tools, it anticipates reconstructing how the experiences of the majority – who survived – were shaped by their socio-cultural circumstances, and tracing how those experiences changed over time, particularly in relation to advances in medical technology and public health. Expected outcomes include insight into historical responses to pandemics, as well as enhanced knowledge of the emergence of modern techniques for regulating public health, with benefits for our understanding of similar challenges in the present day. Read moreRead less