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Encephalitis, or inflammation of the brain tissue, is a complex disease and children are the most commonly affected. The Australian Childhood Encephalitis (ACE) Study, a national surveillance study, aims to describe the burden and characteristics of this disease in Australian children. The Discovery of Infectious aetiologies in Cryptic Encephalitis (DICE) study aims to perform cutting edge diagnostic tests and provide a new understanding of the infectious basis to encephalitis in Australia.
Targeted Molecular Therapies And Predictive Biomarkers In A Novel Orthotopic Xenograft Model Of Oesophageal Carcinoma
Funder
National Health and Medical Research Council
Funding Amount
$120,253.00
Summary
Oesophageal cancer is the most rapidly increasing malignancy in Western society. This disease often presents in advanced stages with poor response to established medical and surgical therapies. Our aim is to develop a novel mouse model of oesophageal cancer, allowing us to tailor cancer-inhibiting molecular treatments to individual patients by predicting therapeutic success or resistance with the use of cellular markers identified in our animal mode.