Discovery Early Career Researcher Award - Grant ID: DE120102878
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Mobile phone text reminders to modify behaviours and prevent cardiovascular disease. Strategies are needed to improve adherence to behavioural and medical preventative treatments for heart disease. Brief informative reminders sent via mobile phone text message have potential as a cheap and safe method of improving behavioural change and adherence to treatments in people at risk of cardiovascular disease.
Discovery Early Career Researcher Award - Grant ID: DE200101618
Funder
Australian Research Council
Funding Amount
$397,241.00
Summary
Reproducibility and transparency in the synthesis of research findings. This project aims to evaluate the reproducibility and transparency of systematic reviews and meta-analyses of the effects of health, social, behavioural and educational interventions. The project expects to determine how reliable, trustworthy, and reusable syntheses of research findings are, and provide critical insight into the education and technical infrastructure needed to improve them. Expected outcomes of the project i ....Reproducibility and transparency in the synthesis of research findings. This project aims to evaluate the reproducibility and transparency of systematic reviews and meta-analyses of the effects of health, social, behavioural and educational interventions. The project expects to determine how reliable, trustworthy, and reusable syntheses of research findings are, and provide critical insight into the education and technical infrastructure needed to improve them. Expected outcomes of the project include new methods to enhance open and reproducible research practices in research synthesis, regardless of discipline. This should provide significant benefits beyond the DECRA, such as more credible evidence to inform government policies and professional society guideline recommendations.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100030
Funder
Australian Research Council
Funding Amount
$425,486.00
Summary
Improving the use of antimicrobials in Australian veterinary practices. This project aims to understand the drivers for antimicrobial use in veterinary medicine and develop methods to improve appropriate antimicrobial use in animals. This project expects to generate new knowledge in the area of veterinary antimicrobial stewardship using an innovative interdisciplinary approach. The project's use of new technology is expected to result in the development of novel tools that enhance capacity to ad ....Improving the use of antimicrobials in Australian veterinary practices. This project aims to understand the drivers for antimicrobial use in veterinary medicine and develop methods to improve appropriate antimicrobial use in animals. This project expects to generate new knowledge in the area of veterinary antimicrobial stewardship using an innovative interdisciplinary approach. The project's use of new technology is expected to result in the development of novel tools that enhance capacity to address antimicrobial stewardship in veterinary medicine and build institutional collaborations. This should provide significant benefits such as improved antimicrobial use in animals and evidence for which antimicrobial stewardship policicies can be developed in veterinary medicine.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100623
Funder
Australian Research Council
Funding Amount
$354,000.00
Summary
Unquiet Minds: Psychiatry in World War Two and its aftermaths. This project aims to provide the first comprehensive account of psychiatry in World War Two and its consequences in American, British and Australian contexts. World War Two was a watershed in the theory and practice of psychiatry in the western world, yet it figures less in the literature than the shell shock of World War One and the post-traumatic stress disorder of the Vietnam War. The projects aims to investigate the diverse patie ....Unquiet Minds: Psychiatry in World War Two and its aftermaths. This project aims to provide the first comprehensive account of psychiatry in World War Two and its consequences in American, British and Australian contexts. World War Two was a watershed in the theory and practice of psychiatry in the western world, yet it figures less in the literature than the shell shock of World War One and the post-traumatic stress disorder of the Vietnam War. The projects aims to investigate the diverse patient cohorts – such as prisoners of war, veterans and children separated from caregivers – encountered by psychiatrists and the impact of the theories and practices that resulted from these interactions. It expects to provide historical context for current psychiatric concepts and practices.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120100796
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Androgens and ovarian function. This innovative project aims to identify the role androgens play in the complex processes required for successful ovarian follicle development and ovulation. The project aims to identify androgen regulated pathways that orchestrate follicle development, which will have significance in the control of fertility and the advancement of reproductive technologies.
Discovery Early Career Researcher Award - Grant ID: DE120100304
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Biomimetic systems for species preservation and fertility restoration. Using a novel 3-D culture system the project will examine the biomechanics of ovary follicle and egg development in vitro, generating new knowledge with directly translatable research outcomes. In vitro egg production has implications for human fertility and threatened species preservation, significantly benefitting health and biodiversity in Australia.
Discovery Early Career Researcher Award - Grant ID: DE140100135
Funder
Australian Research Council
Funding Amount
$395,199.00
Summary
Understanding equine incretins: a novel approach to laminitis prevention. Laminitis is a crippling foot disease in horses which incurs significant economic and social costs. Recent studies have shown that persistently high insulin concentrations can trigger laminitis, and that high insulin levels are caused by the excessive release of hormones called incretins. This project aims to determine the role of incretins and their receptors in causing abnormal equine insulin secretion. The distribution ....Understanding equine incretins: a novel approach to laminitis prevention. Laminitis is a crippling foot disease in horses which incurs significant economic and social costs. Recent studies have shown that persistently high insulin concentrations can trigger laminitis, and that high insulin levels are caused by the excessive release of hormones called incretins. This project aims to determine the role of incretins and their receptors in causing abnormal equine insulin secretion. The distribution of equine incretin receptors will be described for the first time, and the consequences of incretin receptor binding will be characterised. Understanding equine incretin biology may lead to novel therapies for laminitis.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100403
Funder
Australian Research Council
Funding Amount
$468,582.00
Summary
Defining how gut bacteria regulate metabolism: a role for gut serotonin. This project aims to understand how serotonin-producing cells in the gut interact with gut bacteria (the microbiome), using a combination of cells in culture and live germ-free and genetically modified mice. This project expects to generate new knowledge regarding cellular interactions that underlie important physiological pathways, such as the control of blood glucose and fat storage. The intended outcomes of this project ....Defining how gut bacteria regulate metabolism: a role for gut serotonin. This project aims to understand how serotonin-producing cells in the gut interact with gut bacteria (the microbiome), using a combination of cells in culture and live germ-free and genetically modified mice. This project expects to generate new knowledge regarding cellular interactions that underlie important physiological pathways, such as the control of blood glucose and fat storage. The intended outcomes of this project are to identify how gut bacteria communicate with serotonin-producing cells to regulate metabolism, and whether diet acts via a gut microbiome-serotonin axis to impact physiology. The expected benefit of this project will be to provide a new understanding of highly complex physiological systems that regulate our health.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100803
Funder
Australian Research Council
Funding Amount
$365,094.00
Summary
Impact of screen time on preschoolers’ social skills and cognitive function. This project aims to determine how the quantity and nature of screen time interacts with parental co-participation to affect pre-schoolers’ social skills and cognitive functioning. Seventy per cent of pre-schoolers exceed current screen time guidelines and this causes considerable concern among Australian parents. This project will assist in evaluating how much, and which types, of screen time have benefits for social ....Impact of screen time on preschoolers’ social skills and cognitive function. This project aims to determine how the quantity and nature of screen time interacts with parental co-participation to affect pre-schoolers’ social skills and cognitive functioning. Seventy per cent of pre-schoolers exceed current screen time guidelines and this causes considerable concern among Australian parents. This project will assist in evaluating how much, and which types, of screen time have benefits for social skills and cognitive functioning. It will also provide insights into the ways parents may best support these outcomes. Findings are expected to provide evidence for policy development and inform programs to support healthy behaviours to give young children the best start in life.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120102914
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Membrane protein function in its native lipid environment characterised by solid-state nuclear magnetic resonance. Membrane proteins play an important role for cell function and have vast medical implications, whereas their function is crucially dependent on mechanisms related to their embedding in the membrane. These features will be characterised by newly developed spectroscopic methods, which will further contribute to an improved understanding of diseases.