Circulating Tumour DNA To Monitor Treatment Response And Resistance In Chronic Lymphocytic Leukaemia
Funder
National Health and Medical Research Council
Funding Amount
$876,950.00
Summary
Many cancers shed small amounts of DNA (ctDNA) into the patient’s bloodstream and recent advances in genomic technologies now allow levels of ctDNA to be accurately measured in the blood. Changes in ctDNA levels have potential to be used as specific markers of disease progression and/or response to cancer therapy. This project will evaluate if ctDNA can be used to monitor treatment responses and individualise treatment decisions in patients with chronic lymphocytic leukaemia.
Scalability Of The Transform-Us! Program To Promote Children's Physical Activity And Reduce Prolonged Sitting In Victorian Primary Schools
Funder
National Health and Medical Research Council
Funding Amount
$549,823.00
Summary
Transform-Us! is an innovative primary school program that has been found to substantially increase children’s physical activity levels, reduce sitting time and benefit health. With simple changes to the school and classroom environments and teaching practices (eg, standing lessons) we will work with partners in the education and health systems to translate this program across Victorian primary schools to determine the real-world implementation and impact of this program over 5 years.
Optimising Early Interventions For Young People With Emerging Mood Disorder
Funder
National Health and Medical Research Council
Funding Amount
$2,653,052.00
Summary
One of our greatest health challenges is to develop highly-personalised interventions for teenagers and young adults with emerging mood disorders, like major depression or bipolar disorder. This new Australian centre combines our national expertise and links it with research innovation and training in key European and North American centres. It tests the viability of selecting the best treatments for young people with mood disorders on the basis of novel genetic, neuropsychological, circadian, i ....One of our greatest health challenges is to develop highly-personalised interventions for teenagers and young adults with emerging mood disorders, like major depression or bipolar disorder. This new Australian centre combines our national expertise and links it with research innovation and training in key European and North American centres. It tests the viability of selecting the best treatments for young people with mood disorders on the basis of novel genetic, neuropsychological, circadian, imaging, immunological or clinical methods.Read moreRead less
Accelerated Finite-time Learning and Control in Cyber-Physical Systems. Efficient learning and control in cyber-physical systems such as smart grids and robotic systems are very important for achieving economic and social benefits. This project aims to establish a breakthrough accelerated finite-time dynamics theory and technology to assist in delivering efficient learning and control. Expected outcomes include new distributed accelerated finite-time dynamics based learning and control algorithm ....Accelerated Finite-time Learning and Control in Cyber-Physical Systems. Efficient learning and control in cyber-physical systems such as smart grids and robotic systems are very important for achieving economic and social benefits. This project aims to establish a breakthrough accelerated finite-time dynamics theory and technology to assist in delivering efficient learning and control. Expected outcomes include new distributed accelerated finite-time dynamics based learning and control algorithms and tools for optimal operations in cyber-physical systems. This should provide significant benefits including a practical technology for industry applications in smart grids and robotic systems, and training of the next generation engineers in this technology for Australia.Read moreRead less
Protecting Occupants in Vehicle Rollover Crashes. This project addresses a public health issue involving rollover crashes. It will help prevent 340 deaths, 6000 injuries and save $3.6 billion annually in Australia and many fold this number internationally. A dynamic rollover crashworthiness test protocol, that ensures efficient and economical vehicle rollover protection systems are designed and manufactured, will be provided to consumer and regulatory bodies to consider and implement. In additio ....Protecting Occupants in Vehicle Rollover Crashes. This project addresses a public health issue involving rollover crashes. It will help prevent 340 deaths, 6000 injuries and save $3.6 billion annually in Australia and many fold this number internationally. A dynamic rollover crashworthiness test protocol, that ensures efficient and economical vehicle rollover protection systems are designed and manufactured, will be provided to consumer and regulatory bodies to consider and implement. In addition, much needed Occupational Health & Safety information regarding vehicle rollover crashworthiness, which provide a safe work place environment for professional drivers and employees using vehicles, will be supplied to industry fleet managers, defence and emergency services.Read moreRead less
Non-contact Integrity Assessment of Façade Panels of High-rise Buildings. Disintegration of the external façade (with tiles, plates, etc.) of high-rise buildings presents a great challenge and a threat to community. This project develops fundamental knowledge and algorithms that underpin the deployment of a new technique for fast and automated quantitative integrity assessment of façade units of high-rise buildings, integrating mechanisms of directional acoustic waves, vibro-acoustics of façade ....Non-contact Integrity Assessment of Façade Panels of High-rise Buildings. Disintegration of the external façade (with tiles, plates, etc.) of high-rise buildings presents a great challenge and a threat to community. This project develops fundamental knowledge and algorithms that underpin the deployment of a new technique for fast and automated quantitative integrity assessment of façade units of high-rise buildings, integrating mechanisms of directional acoustic waves, vibro-acoustics of façade tiles or panels, laser sensing technology, deep learning algorithms and drone technology. Outcomes of this project are critical for implementing the new technology for enhanced safety to community and the development of new procedures for driving down maintenance costs of the external façade of high-rise buildings.Read moreRead less
Comfort and ergonomics: Innovative seating solutions for commercial vehicles. Comfort and ergonomics: Innovative seating solutions for commercial vehicles. This project aims to develop a 6-degree-of-freedom seating system for commercial vehicles, including heavy duty trucks and mobile machinery, to reduce unwanted multiple directional vibrations to the driver’s body. Long-term exposure to vibrations from uneven road surfaces, vibrating tools, and vibrating machinery affects driver comfort, fatig ....Comfort and ergonomics: Innovative seating solutions for commercial vehicles. Comfort and ergonomics: Innovative seating solutions for commercial vehicles. This project aims to develop a 6-degree-of-freedom seating system for commercial vehicles, including heavy duty trucks and mobile machinery, to reduce unwanted multiple directional vibrations to the driver’s body. Long-term exposure to vibrations from uneven road surfaces, vibrating tools, and vibrating machinery affects driver comfort, fatigue and safety, and can also cause neck and shoulder pain, lower back injuries, and spinal injuries. The expected outcome of the project is a comfortable and ergonomic seating system that, agriculture, transportation, mining and construction vehicles, both in Australia and internationally, can widely use.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
Buffering the ecosystem impact of invasive cane toads. This project aims to address the devastating ecological problems caused by invasive species, by developing a novel approach that does not rely upon eradicating the invader through training vulnerable native predators not to eat toxic cane toads. Expected outcomes of this project include building a broad coalition of conservation-focused groups, from private land-owners and local businesses through to Indigenous groups and government and non- ....Buffering the ecosystem impact of invasive cane toads. This project aims to address the devastating ecological problems caused by invasive species, by developing a novel approach that does not rely upon eradicating the invader through training vulnerable native predators not to eat toxic cane toads. Expected outcomes of this project include building a broad coalition of conservation-focused groups, from private land-owners and local businesses through to Indigenous groups and government and non-government agencies across the entire Kimberley region. It will also result in the evaluation of methods for deployment of taste-aversion at a landscape scale. This should provide significant benefits by conserving vulnerable fauna and building a powerful network within a region of high biodiversity in tropical Australia.Read moreRead less
Evaluating Cancer Screening: Context, Evidence, Values And Ethics
Funder
National Health and Medical Research Council
Funding Amount
$572,460.00
Summary
The research and clinical communities are divided over whether certain forms of cancer screening do more harm than good. This project asks: What is the right thing to do about cancer screening now? Using robust qualitative methodologies, we will study real cases of cancer screening and analyse their ethical implications. Drawing on this data and analysis, we will produce tools to help policy-makers, consumers and professionals make good decisions about cancer screening in future.