Predicting Treatment Response To Onabotulinumtoxin-a In MS-related Tremor: A Combined Clinical, Electrophysiological And Neuroimaging Approach.
Funder
National Health and Medical Research Council
Funding Amount
$546,359.00
Summary
Shaking (tremor) of the upper limbs occur in many people with multiple sclerosis (MS). We have previously shown that botulinum toxin (Botox) injections could help reduce tremor. This study aims to study the effect of Botox in a larger group of people with MS and will include detailed MRI scans and electrical tremor monitoring tests to define the underlying changes in the brain that causes tremor. The results will help make Botox available as a tremor treatment for people with MS.
Tremor And Cognition In Multiple Sclerosis: Implementing Novel Treatments And Computerized Monitoring Strategies.
Funder
National Health and Medical Research Council
Funding Amount
$303,014.00
Summary
This research program aims to study two disabling symptoms of multiple sclerosis namely upper limb shaking, or tremor, and memory dysfunction. The first project will develop a new treatment for MS arm tremor, Botulinum toxin injections, into routine clinical practice. The second project aims to make available a computerised test of memory that can be done in clinic waiting rooms or at home. This will help neurologists to rapidly pick up changes in memory in a person with MS and improve care.