Final frontier in computational modelling of movement. This project aims to create the computational models and methods needed to advance current understanding of musculoskeletal function during movement. Humans must maintain their capacity to move in order to maintain quality-of-life. Predictive modelling is potentially the most powerful approach for understanding musculoskeletal function during movement. Current computational methods are too slow and unreliable to deliver predictive simulation ....Final frontier in computational modelling of movement. This project aims to create the computational models and methods needed to advance current understanding of musculoskeletal function during movement. Humans must maintain their capacity to move in order to maintain quality-of-life. Predictive modelling is potentially the most powerful approach for understanding musculoskeletal function during movement. Current computational methods are too slow and unreliable to deliver predictive simulations of movement using realistic models of muscle and joint anatomy. This project expects to create the next generation of methods and algorithms needed to enable predictive modelling of movement. Predictive simulations will provide new insights into how muscles stabilise and control movements of the spine, pelvis and lower limbs during daily activities such as walking.Read moreRead less
Fundamental theoretical and experimental investigation of cartilage mechanics. Arthritis and chronic joint symptoms are one of the leading causes of disability in the community, yet a fundamental understanding of joint mechanics has yet to be realised. The aim of this project is to develop a new state-of-the-art mathematical model describing cartilage behaviour in humans. The model will explain how activities like walking maintain healthy cartilage by transferring growth factors through the tiss ....Fundamental theoretical and experimental investigation of cartilage mechanics. Arthritis and chronic joint symptoms are one of the leading causes of disability in the community, yet a fundamental understanding of joint mechanics has yet to be realised. The aim of this project is to develop a new state-of-the-art mathematical model describing cartilage behaviour in humans. The model will explain how activities like walking maintain healthy cartilage by transferring growth factors through the tissue, and quantitatively explain how wear is minimised in cartilage through weeping lubrication. This model will progress our understanding of cartilage mechanics in health and disease, and so help Australians age well and productively.Read moreRead less
A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing ....A new energy absorption system for brain injury mitigation. This research aims to propose and investigate a next generation high-energy absorbing helmet pad that will protect the Australian Defence Force soldiers against both ballistic and blast threats. New fundamental knowledge in the area of high-energy absorbing metamaterials will be obtained by using numerical modelling and experimental studies. The expected outcomes of the project include the development of a new wearable energy absorbing pad which can be used as the next generation combat helmet liners and accessories. The novel high-performance energy absorption system will have a wide range of direct applications in future personal armour, as well as sports gears and elderly healthcare products.Read moreRead less
Multi-scale modeling of transport through deformable porous materials. Understanding solute transport through porous materials is essential because it provides a technical basis for answering many important questions in society today-how can humans avoid 'brittle bones', how to design durable infrastructure, how to safely store wastes (e.g. hazardous and municipal). Solution of each of these problems requires innovation in model development, new method of analysis, and insightful interpretation ....Multi-scale modeling of transport through deformable porous materials. Understanding solute transport through porous materials is essential because it provides a technical basis for answering many important questions in society today-how can humans avoid 'brittle bones', how to design durable infrastructure, how to safely store wastes (e.g. hazardous and municipal). Solution of each of these problems requires innovation in model development, new method of analysis, and insightful interpretation of results. While theoretical developments of this project are general, in the sense that they are not restricted to particular engineering disciplines, the four chosen applications closely align with two major research priorities namely An Environmental Sustainable Australia and Promoting and Maintaining Good Health.Read moreRead less
Quantitative micro-computed tomography for mechanobiological measurement. This project aims to investigate novel measurement approaches for complex cartilage and joint systems by utilising engineering and software design, imaging physics and musculoskeletal biology. Accurate measurement of these living biological systems in action expects to generate new knowledge and a fundamental understanding of their mechanobiological processes. This project will enhance understanding of this complex system ....Quantitative micro-computed tomography for mechanobiological measurement. This project aims to investigate novel measurement approaches for complex cartilage and joint systems by utilising engineering and software design, imaging physics and musculoskeletal biology. Accurate measurement of these living biological systems in action expects to generate new knowledge and a fundamental understanding of their mechanobiological processes. This project will enhance understanding of this complex system and facilitate our capacity to innovate functional solutions in biomedical engineering and biosciences.Read moreRead less
Influence of electromagnetic emissions from mobile phones on nervous function in the human brain and heart. This research will investigate the influence of mobile phone electromagnetic exposures on the nervous function of the human brain and heart. Brain activity will be monitored by EEG recordings, and heart function will be measured by blood pressure and ECG. As far as possible the methodologies employed will be consistent with previous reported studies in order to allow comparisons, and use ....Influence of electromagnetic emissions from mobile phones on nervous function in the human brain and heart. This research will investigate the influence of mobile phone electromagnetic exposures on the nervous function of the human brain and heart. Brain activity will be monitored by EEG recordings, and heart function will be measured by blood pressure and ECG. As far as possible the methodologies employed will be consistent with previous reported studies in order to allow comparisons, and use standardised quantifiable metrics so that the biological significance of the data can be meaningfully interpreted. The outcomes of this project will address uncertainties in the present data which are of concern to national and international regulatory and health agencies.Read moreRead less
Intelligent Freeform Bio-fabrication for Customised Anatomical Structures for Reconstructive Surgery. This project contributes towards the ARC priority goal on advanced materials and frontier technologies by developing an intelligent freeform biofabrication facility to produce accurate anatomical biocompatible replica structures and implants for reconstructive surgery. The products, produced from patient's CT or MRI scan data, will contribute to complex surgical procedure planning and patient ed ....Intelligent Freeform Bio-fabrication for Customised Anatomical Structures for Reconstructive Surgery. This project contributes towards the ARC priority goal on advanced materials and frontier technologies by developing an intelligent freeform biofabrication facility to produce accurate anatomical biocompatible replica structures and implants for reconstructive surgery. The products, produced from patient's CT or MRI scan data, will contribute to complex surgical procedure planning and patient education. The proposed facility will be based on multifunctional freeform fabrication process supported by intelligent software tools and database of biocompatible materials. The prospective outcomes are likely to have an excellent commercial and patenting potential that may help Australia become a leader in biomanufacturing technology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100114
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
Multi-scale imaging and characterisation facility for biological structure and function. Discovery in biology will lead to significant social and economic impact improving Australians' lives. This facility will allow researchers to study the micro and nanoscales structure and function of cells, tissues and organs. The knowledge gained will have direct benefits and applications to human and animal health, drug and food technology.
Virtual testing of orthopaedic devices as part of the design and development process: strategies to account for patient and surgical variability. Novel computational tools will be developed through this project to help account for patient and surgical variability in the design of orthopaedic implants, such as hip and knee replacements and spinal products. These tools will reduce the design time, give greater insight in implant performance and ultimately lead to safer implants with improved longe ....Virtual testing of orthopaedic devices as part of the design and development process: strategies to account for patient and surgical variability. Novel computational tools will be developed through this project to help account for patient and surgical variability in the design of orthopaedic implants, such as hip and knee replacements and spinal products. These tools will reduce the design time, give greater insight in implant performance and ultimately lead to safer implants with improved longevity.Read moreRead less
Tissue-like, nonlinearly elastic nanobiomaterials for soft tissue regeneration. The purpose of this project is to advance the discipline of soft tissue engineering and regeneration with novel biomaterials, nanotechnology and novel clinical treatment concepts. The key outcomes include new elastic tissue-like nanobiomaterials, new varieties of medical implants and innovative treatment methodology.