Industrial Transformation Training Centres - Grant ID: IC170100016
Funder
Australian Research Council
Funding Amount
$3,123,492.00
Summary
ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therap ....ARC Training Centre for Personalised Therapeutics Technologies. The ARC Training Centre for Personalised Therapeutics Technologies aims to create and develop the skills and technology to benefit from the transformative impacts that cell/organ-on-a-chip technology will have on the medtech/pharma industries. By combining microfluidics-based/real-time technologies with personalised medicine the Training Centre will provide industry growth opportunities through improved screening of potential therapeutics. The use of an individual patient’s cellular and molecular research findings will ultimately enable personalised diagnostic and therapeutic decisions.Read moreRead less
Unveiling the epigenome dynamics through the pluripotency continuum. This project aims to utilise stem cells and genomics based technologies, in combination with new computational algorithms to dissect the fundamental molecular events that drive the first steps during development. The project is expected to unveil the basic mechanisms underpinning how genes driving the developmental master plan are controlled in cells that have the capacity to give rise to the whole organism and placenta. The kn ....Unveiling the epigenome dynamics through the pluripotency continuum. This project aims to utilise stem cells and genomics based technologies, in combination with new computational algorithms to dissect the fundamental molecular events that drive the first steps during development. The project is expected to unveil the basic mechanisms underpinning how genes driving the developmental master plan are controlled in cells that have the capacity to give rise to the whole organism and placenta. The knowledge gained from this work will inform and guide future novel approaches, such as in assisted reproductive technologies or regenerative medicine.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC190100026
Funder
Australian Research Council
Funding Amount
$4,969,663.00
Summary
ARC Training Centre for Cell and Tissue Engineering Technologies. The ARC Training Centre for Cell and Tissue Engineering Technologies aims to provide training to create a highly skilled workforce for the tissue engineering and regenerative medicine sector and to enhance research performance and innovation in Australia through fundamental and applied research carried out in industry-led PhD projects. The research aims to address major aspects of the manufacturing and commercialisation pathway an ....ARC Training Centre for Cell and Tissue Engineering Technologies. The ARC Training Centre for Cell and Tissue Engineering Technologies aims to provide training to create a highly skilled workforce for the tissue engineering and regenerative medicine sector and to enhance research performance and innovation in Australia through fundamental and applied research carried out in industry-led PhD projects. The research aims to address major aspects of the manufacturing and commercialisation pathway and barriers faced by the sector, namely improving process efficiencies, enabling early-stage scale-up (cell/tissue) and development of the sector's supply chain. The knowledge created and research undertaken would help to accelerate commercialisation in regenerative medicine, tissue engineering and cell therapies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100073
Funder
Australian Research Council
Funding Amount
$1,150,000.00
Summary
A femtosecond beamline for time-resolved momentum microscopy. This project aims to obtain a femtosecond high-harmonic generation beamline that will be integrated with a photoemission electron microscope to create Australia’s first time-resolved momentum microscope. This project expects to use ultrafast spectromicroscopy to observe the changes to the excited electron motion within materials after they absorb light. Expected outcomes of this project include improving our understanding of light-dri ....A femtosecond beamline for time-resolved momentum microscopy. This project aims to obtain a femtosecond high-harmonic generation beamline that will be integrated with a photoemission electron microscope to create Australia’s first time-resolved momentum microscope. This project expects to use ultrafast spectromicroscopy to observe the changes to the excited electron motion within materials after they absorb light. Expected outcomes of this project include improving our understanding of light-driven physical and chemical processes that occur in materials and optoelectronic devices. This should provide significant benefits through the development of new cost effective and efficient materials for energy harvesting, sensors and photocatalysts.Read moreRead less
Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are inn ....Advancing the visualisation and quantification of nephrons with MRI. . This project aims to characterise key components of nephrons, the glomeruli and tubules, using magnetic resonance imaging without contrast agents, in combination with Deep Learning and super-resolution techniques. Nephrons, the basic functional unit of the kidney, are critical to the maintenance of the body’s homeostasis. Their number and architecture are critical determinants of kidney function. The expected outcomes are innovative semi-automated nephron visualisation and quantitation tools that enable efficient renal phenotyping. Techniques tailored to widely accessible preclinical research scanners are expected to accelerate research into genetic and environmental factors affecting kidney microstructure in embryonic and post-natal life.Read moreRead less
A spatio-temporal partitioning approach to colloidal flows in porous media. This project aims to develop an efficient multi-scale laboratory-based modelling framework for colloidal suspensions flow in porous media by utilizing recent advances in 3D/4D image-based geometrical/topological analysis. Regional partitioning techniques based on local structural measures are used to observe the penetration/retention of colloids into identified zones. Zone-dependent colloid interaction probabilities for ....A spatio-temporal partitioning approach to colloidal flows in porous media. This project aims to develop an efficient multi-scale laboratory-based modelling framework for colloidal suspensions flow in porous media by utilizing recent advances in 3D/4D image-based geometrical/topological analysis. Regional partitioning techniques based on local structural measures are used to observe the penetration/retention of colloids into identified zones. Zone-dependent colloid interaction probabilities for computational modelling are derived from fundamental relationships. Expected outcomes of this project include a full-scale modelling capability for heterogeneous samples validated by experiment and the extraction of robust model coefficients for newly developed theory for colloid-suspension transport through porous media.Read moreRead less