Australian Laureate Fellowships - Grant ID: FL220100202
Funder
Australian Research Council
Funding Amount
$3,221,432.00
Summary
“New ways to see” - Reimagining Electron Microscopy . Understanding materials at the level of individual atoms can be critical for understanding their properties. This program aims to develop new ways to measure the structure of matter at the level of atoms by reimagining the fundamental concepts behind an electron microscope. This will enable subtle classes of structures in materials to be seen, that were previously not visible. This new knowledge will provide fundamental insight into the prope ....“New ways to see” - Reimagining Electron Microscopy . Understanding materials at the level of individual atoms can be critical for understanding their properties. This program aims to develop new ways to measure the structure of matter at the level of atoms by reimagining the fundamental concepts behind an electron microscope. This will enable subtle classes of structures in materials to be seen, that were previously not visible. This new knowledge will provide fundamental insight into the properties of materials and how they can be engineered to deliver new functions. Expected outcomes include a microscope with unprecedented sensitivity to atomic scale structures and new understanding of material’s properties. Read moreRead less
Australian Laureate Fellowships - Grant ID: FL160100139
Funder
Australian Research Council
Funding Amount
$2,965,538.00
Summary
Outside-In: Strain stiffening as a key to cell control. Outside-In: Strain stiffening as a key to cell control. This research project aims to unravel the highly complex mechanical behaviour of the extracellular matrix, and develop a whole new class of sophisticated and responsive extracellular matrix (ECM) materials. In any multicellular organism, the ECM provides cells with essential mechanical (such as strain stiffening) and biochemical support. The ECM is also critical for biological processe ....Outside-In: Strain stiffening as a key to cell control. Outside-In: Strain stiffening as a key to cell control. This research project aims to unravel the highly complex mechanical behaviour of the extracellular matrix, and develop a whole new class of sophisticated and responsive extracellular matrix (ECM) materials. In any multicellular organism, the ECM provides cells with essential mechanical (such as strain stiffening) and biochemical support. The ECM is also critical for biological processes inside the cell, including proliferation, differentiation and migration. Exactly how the physical and chemical properties of ECMs on the outside of the cell modify the behaviour of a cell on the inside remains unclear. Outcomes would include a blueprint for synthetic ECMs, pushing the boundaries of materials development in the biological and life sciences.Read moreRead less