Heparin Induced Thrombocytopenia (HIT): Further Characterization Of Disease Mechanism Will Improve Patient Treatment
Funder
National Health and Medical Research Council
Funding Amount
$456,484.00
Summary
Thrombus formation occurs as a side effect of heparin treatment in many patients. This condition is called Heparin Induced Thrombocytopenia (HIT). The clots may be stabilised by secretions from cells called neutrophils. In this project we will study this possibility using a mouse model of HIT and will explore therapeutic approaches to inhibit clot stabilisation.
Through this Australia Fellowship Prof Jackson aims to identify an entirely new approach to the treatment of heart attacks and stroke; namely the development of innovative blood clotting therapies that prevent the disease-causing effects of disturbed blood flow. This research program brings together a number of world class researchers at Monash University, the Walter and Eliza Hall Institute and RMIT University in Melbourne, with scientists at The Scripps Research Institute in San Diego to tackl ....Through this Australia Fellowship Prof Jackson aims to identify an entirely new approach to the treatment of heart attacks and stroke; namely the development of innovative blood clotting therapies that prevent the disease-causing effects of disturbed blood flow. This research program brings together a number of world class researchers at Monash University, the Walter and Eliza Hall Institute and RMIT University in Melbourne, with scientists at The Scripps Research Institute in San Diego to tackle this important medical problem. This unique research program aims to place Australia at the forefront of discovery and development of innovative new therapies for the treatment of heart disease and strokeRead moreRead less