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Ketamine Therapy Among Patients With Treatment-resistant Depression: A Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,069,382.00
Summary
In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.
Influence of an innovative shoe design on lower limb joint loading during walking. This project will provide new knowledge about the effects of shoe design features on lower limb loading and the influence of obesity and knee condition on the shoe-mediated biomechanical effects. This will be of relevance to researchers and clinicians. It is also likely to contribute to a marketable commercial product, a shoe designed to reduce knee loading. This shoe has the potential to contribute to reducing th ....Influence of an innovative shoe design on lower limb joint loading during walking. This project will provide new knowledge about the effects of shoe design features on lower limb loading and the influence of obesity and knee condition on the shoe-mediated biomechanical effects. This will be of relevance to researchers and clinicians. It is also likely to contribute to a marketable commercial product, a shoe designed to reduce knee loading. This shoe has the potential to contribute to reducing the societal and personal burden of knee osteoarthritis, one of the most prevalent and costly chronic conditions in the developed world. Read moreRead less
Defining Epigenetic Predictors Of Long-term Outcomes Of Preterm Birth
Funder
National Health and Medical Research Council
Funding Amount
$409,408.00
Summary
On average, those born premature do worse health-wise than those born at term. However, some do worse than others. Our aim is to identify these people at birth to better help doctors and parents to closely monitor their health. For this, we will be “reading the diary of pregnancy” in the molecules added to chromosomes in blood during pregnancy in young adults with will characterised states of health. We will analyse DNA from blood that we will extract from stored heel prick spots.
New Polymers for Cellulose-based Bioplastics. We will design new cellulose derivatives by combining carefully engineered synthetic polymers to cellulose. We will explore the fundamental science underpinning the manufacture of these bioplastics, and apply the concept to the design of two new materials, with (super)hydrophobic and antibacterial properties. These materials have the potential to replace synthetic plastics, which comprise one of the major outputs of the chemical industry worldwide. P ....New Polymers for Cellulose-based Bioplastics. We will design new cellulose derivatives by combining carefully engineered synthetic polymers to cellulose. We will explore the fundamental science underpinning the manufacture of these bioplastics, and apply the concept to the design of two new materials, with (super)hydrophobic and antibacterial properties. These materials have the potential to replace synthetic plastics, which comprise one of the major outputs of the chemical industry worldwide. Plastic is present everywhere in human life, but its manufacture and disposal have a strong negative impact on the environment; the new materials manufactured in this project are viable alternatives to plastics, and are sustainable from a production and disposal point of view.Read moreRead less
How parents manage climate anxiety: coping and hoping for the whole family. This project studies how Australian parents manage climate anxiety for themselves and their families. Using mixed-methods/mixed-media approaches, it examines whether an increase in climate disasters is accelerating the spread of collective anxiety amongst families, how parents manage this anxiety for their children and partners, and if there are associated mental health burdens and gendered inequities in this management. ....How parents manage climate anxiety: coping and hoping for the whole family. This project studies how Australian parents manage climate anxiety for themselves and their families. Using mixed-methods/mixed-media approaches, it examines whether an increase in climate disasters is accelerating the spread of collective anxiety amongst families, how parents manage this anxiety for their children and partners, and if there are associated mental health burdens and gendered inequities in this management. It also looks at climate anxiety management across generations and climate histories, drawing out pessimistic/optimistic narratives about the future to enable action, resilience, and hope. It will produce an evidence base and photo-voice/documentary resources to help parents and support organisations combat climate anxiety.Read moreRead less
Governing the blue economy in maritime Asia-Pacific. This project aims to examine the drivers, character and effects of Blue Economy governance, a highly influential agenda intended to reconcile economic growth with ocean conservation. Analysis of Blue Economy governance in China and the Philippines seeks to reveal how this agenda is represented, contested and implemented at regional, national and local scales. Expected outcomes include new knowledge concerning the influence and impacts of marit ....Governing the blue economy in maritime Asia-Pacific. This project aims to examine the drivers, character and effects of Blue Economy governance, a highly influential agenda intended to reconcile economic growth with ocean conservation. Analysis of Blue Economy governance in China and the Philippines seeks to reveal how this agenda is represented, contested and implemented at regional, national and local scales. Expected outcomes include new knowledge concerning the influence and impacts of maritime governance in the region. This project has the potential to inform more socially equitable and environmentally sustainable governance outcomes.Read moreRead less
A socio-cultural analysis of eating disorders among pre-teen boys and girls. This project tackles the tough question of why there has been a dramatic increase in eating disorders amongst very young boys and girls by examining the social conditions of children's lives in contemporary Australia. The findings will provide important information for policy makers, educators and clinicians working with children and families.