Australian Laureate Fellowships - Grant ID: FL120100030
Funder
Australian Research Council
Funding Amount
$2,779,572.00
Summary
Engineering materials for advances in nanomedicine. Nanomedicine is one of the fastest growing areas in nanotechnology. This project will develop next-generation particle systems with engineered properties that are expected to underpin advances in the delivery of therapeutics in the areas of cancer, vaccines, cardiovascular disease and neural health.
Nanoengineered Polymeric Materials for Environmental and Biological Applications. The development of advanced materials with nanoengineered properties promises to revolutionise future industries, including the energy and healthcare sectors. This research program will involve the design, synthesis and assembly of tailored polymers to prepare next-generation, engineered materials. The research will deliver advanced polymeric membranes, tissue engineering scaffolds and vaccine delivery systems. The ....Nanoengineered Polymeric Materials for Environmental and Biological Applications. The development of advanced materials with nanoengineered properties promises to revolutionise future industries, including the energy and healthcare sectors. This research program will involve the design, synthesis and assembly of tailored polymers to prepare next-generation, engineered materials. The research will deliver advanced polymeric membranes, tissue engineering scaffolds and vaccine delivery systems. These materials are expected to provide benefits for Australian citizens in the energy and health sectors and contribute to the development of a robust Australian nanotechnology industry. The projects will also provide opportunities for the development of outstanding young scientists and will foster multidisciplinary collaborations.Read moreRead less
A multimodal approach to unravel the role of surface properties in nanoparticle-cell interactions using models of medical emergencies. The design and development of multimodal nanoparticles seek to expand upon the benefits of nanoparticles by delivering imaging and therapeutic agents to specific organs, enabling detection and treatment of disease in a single procedure. The successful implementation of this technology is dependent on our detailed understanding of the nanoparticle-cell interaction ....A multimodal approach to unravel the role of surface properties in nanoparticle-cell interactions using models of medical emergencies. The design and development of multimodal nanoparticles seek to expand upon the benefits of nanoparticles by delivering imaging and therapeutic agents to specific organs, enabling detection and treatment of disease in a single procedure. The successful implementation of this technology is dependent on our detailed understanding of the nanoparticle-cell interactions. This project will address this very important issue by evaluating a range of surface functionalised nanoparticles in highly significant models of medical emergencies. This project will enable development of advanced therapeutic interventions for cancer, central nervous system injuries, cardiovascular diseases and pregnancy related disorders.Read moreRead less
Optimisation of functional mesoporous materials for low-abundance biomarkers quantification towards biodiagnostic applications. Using state-of-the-art nanotechnology, a novel approach will be developed to quantitatively analyse low abundance peptides and proteins. This will aid in the detection of a biomarker in osteoarthritis, a disease affecting 3.85 million Australians. This project has significance for the early diagnosis and improved treatment of this disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100040
Funder
Australian Research Council
Funding Amount
$1,375,000.00
Summary
An advanced electron microscope facility for nanomaterials, functional materials and minerals. An advanced electron microscope facility for nanomaterials, functional materials and minerals: Recent advances in electron microscopy provide instruments that can resolve at the atomic level and image both morphologically and chemically at these resolutions. These modern instruments are also less complex to operate therefore allowing many more researchers to access them directly. The High Resolution Sc ....An advanced electron microscope facility for nanomaterials, functional materials and minerals. An advanced electron microscope facility for nanomaterials, functional materials and minerals: Recent advances in electron microscopy provide instruments that can resolve at the atomic level and image both morphologically and chemically at these resolutions. These modern instruments are also less complex to operate therefore allowing many more researchers to access them directly. The High Resolution Scanning Transmission Electron Microscope will allow a complete, nano-scale characterisation of natural and synthetic materials in a broad range of scientific, engineering and industrial applications. The Field Emission Scanning Electron Microscope will provide nano-science users with a tool that can image many of the processes in the formation of these nanostructures and particles.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100033
Funder
Australian Research Council
Funding Amount
$1,200,000.00
Summary
In situ Environmental Electron Microscope Facility. This project aims to establish an In situ Environmental Electron Microscope Facility to characterise real-time and dynamic changes in nanomaterials at the atomic scale. We will combine a cutting-edge 'in situ' gas/heating/electrical bias holder with new camera and analysis technology on a transmission electron microscope. This facility will be a sophisticated suite of equipment that will innovate and transform microscopy in Australia to image s ....In situ Environmental Electron Microscope Facility. This project aims to establish an In situ Environmental Electron Microscope Facility to characterise real-time and dynamic changes in nanomaterials at the atomic scale. We will combine a cutting-edge 'in situ' gas/heating/electrical bias holder with new camera and analysis technology on a transmission electron microscope. This facility will be a sophisticated suite of equipment that will innovate and transform microscopy in Australia to image structural and compositional changes of materials under stimuli at a speed and resolution previously unachievable. This project will drive pioneering research in the fields of Materials Science, Chemistry and Catalysis to solve problems in advanced manufacturing, energy, technology and the environment.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100075
Funder
Australian Research Council
Funding Amount
$580,000.00
Summary
Next Generation Small Angle X-Ray Scattering Facility. Next generation small angle X-ray scattering facility: The ability to determine the nanostructure of bulk materials is of utmost importance in an array of cutting-edge research fields. A state-of-the-art small angle X-ray scattering (SAXS) facility will address this for a wide range of materials covering a diverse range of research topics such as energy storage materials, catalytic species, drug delivery systems, protein structures, biologic ....Next Generation Small Angle X-Ray Scattering Facility. Next generation small angle X-ray scattering facility: The ability to determine the nanostructure of bulk materials is of utmost importance in an array of cutting-edge research fields. A state-of-the-art small angle X-ray scattering (SAXS) facility will address this for a wide range of materials covering a diverse range of research topics such as energy storage materials, catalytic species, drug delivery systems, protein structures, biological membranes, medical diagnostics and therapy, magnetic nanosystems, polymers, novel technologies for the clean utilisation of biomass, and minerals processing. The facility will underpin a range of current and planned multidisciplinary research programs leading to vital nanostructural information and innovative research solutions.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100042
Funder
Australian Research Council
Funding Amount
$970,000.00
Summary
Cryo-Focused Ion Beam Facility for soft and hard materials. The multipurpose Cryo-Focused Ion beam scanning electron microscope (Cryo-FIB) Facility aims to provide revolutionary insights into beam sensitive materials and biological molecules at high magnification. This instrument will be a unique configuration and the most advanced of its kind in Australia. It will be fitted with a gallium ion source, cryo-stage, cryo-lift out and cryo-transfer suite and capable of imaging and compositional anal ....Cryo-Focused Ion Beam Facility for soft and hard materials. The multipurpose Cryo-Focused Ion beam scanning electron microscope (Cryo-FIB) Facility aims to provide revolutionary insights into beam sensitive materials and biological molecules at high magnification. This instrument will be a unique configuration and the most advanced of its kind in Australia. It will be fitted with a gallium ion source, cryo-stage, cryo-lift out and cryo-transfer suite and capable of imaging and compositional analysis in two- and three-dimensions and preparing samples for atomic-scale analyses with complementary cryo-microscopies. This equipment aims to facilitate innovative research in the fields of energy materials, advanced manufacturing, nanomaterials and in situ cell and structural biology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100140
Funder
Australian Research Council
Funding Amount
$1,050,000.00
Summary
A multiple ion beam facility for microscopy and nanofabrication. This project aims to establish a powerful multiple ion beam system for nanoscience research. The demand for customised therapies, secure communication and efficient energy harvesting prompts the development of nanoscale devices that can interface and interact with the environment: nanotechnology systems with fully functional sensors, detectors, energy and data processing modules. This project would increase the ability to observe a ....A multiple ion beam facility for microscopy and nanofabrication. This project aims to establish a powerful multiple ion beam system for nanoscience research. The demand for customised therapies, secure communication and efficient energy harvesting prompts the development of nanoscale devices that can interface and interact with the environment: nanotechnology systems with fully functional sensors, detectors, energy and data processing modules. This project would increase the ability to observe and manipulate the structure of materials at the nanometre length-scale. This project is expected to boost Australia’s research capacity in nanoscience and develop materials for nanoelectronics, energy and the environment, and structural materials. These outcomes will benefit Australia’s capacity to develop advanced manufacturing industries.Read moreRead less
Engineering an artificial protein molecular motor. This project aims to use non-motor protein building blocks to construct an artificial protein motor. Nature already uses nanotechnology as the basis for all its machinery, and uses proteins to construct machines. Each protein component in the motor will have a well-understood function; this artificial protein will elucidate how it converts chemical energy to motion. This process is not understood as molecular motors do not obey the same principl ....Engineering an artificial protein molecular motor. This project aims to use non-motor protein building blocks to construct an artificial protein motor. Nature already uses nanotechnology as the basis for all its machinery, and uses proteins to construct machines. Each protein component in the motor will have a well-understood function; this artificial protein will elucidate how it converts chemical energy to motion. This process is not understood as molecular motors do not obey the same principles as macroscopic machines. Comparing the artificial motor with biological motors will provide insight into the workings of natural motors. This project should lead to molecular motors for nanobiotechnology.Read moreRead less