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The proposal builds on innovative technologies patented and published by my group. The project has two specific objectives: 1) to deliver the new generation of intelligent biomedical devices that have the capacity to control infections, inflammation and foreign body response; and 2) to develop a novel, non-invasive and affordable point of care diagnostic technology for early detection of chronic kidney diseases, and kidney and bladder cancers that is much needed in this space of healthcare.
Significance Of Low-level Mosaicism To Intellectual Disability In Paediatric Disorders
Funder
National Health and Medical Research Council
Funding Amount
$483,402.00
Summary
My vision for the next 4 years is to improve outcomes for children and their families with inherited disorders associated with intellectual disability (ID) and autism through earlier diagnosis and intervention. This is of great importance with annual costs of ID close $14.72 billion to the Australian health system, and missed or delayed diagnoses being a significant problem, as ID is found in 1.7% of births, where a specific cause is currently identified in less than half.
Novel Interventions For Comprehensive Prevention Of Mother-to-child Transmission Of HIV-1 In Resource-constrained Settings
Funder
National Health and Medical Research Council
Funding Amount
$474,034.00
Summary
Nearly 2.5 million persons are infected with HIV each year. My vision is to improve the health of vulnerable women and children in resource-constrained settings through comprehensive prevention of mother-to-child transmission of HIV-1. This work aims to i) prevent HIV among women of childbearing age; ii) prevent unintended pregnancies among HIV-infected women; iii) prevent transmission of HIV from mothers to their infants; and iv) provide treatment, care and support for those living with HIV.
Central Blood Pressure: Physiology And Clinical Application
Funder
National Health and Medical Research Council
Funding Amount
$459,270.00
Summary
Current methods used by doctors to measure blood pressure (BP) have many limitations that could result in incorrect diagnosis and inappropriate treatment of high BP (hypertension). This research program will determine the clinical usefulness of new methods to diagnose and treat people with high BP. The underlying mechanisms contributing to high BP will also be examined. The findings will lead to improved ways to identify and more effectively manage people with high BP.