Short silk nanofibre based 3D scaffolds with enhanced biomimicry. This project aims to understand the behaviour of haematopoietic stem cells (HSC) in novel 3D scaffolds based on short silk nanofibres. This will lead to highly functional 3D scaffolding materials that support efficient HSC renewal in vitro. This project aims to overcome the key problem with existing in vitro systems, which lack the morphological and biochemical complexities of native HSC-niche. Since haematopoietic stem cells are ....Short silk nanofibre based 3D scaffolds with enhanced biomimicry. This project aims to understand the behaviour of haematopoietic stem cells (HSC) in novel 3D scaffolds based on short silk nanofibres. This will lead to highly functional 3D scaffolding materials that support efficient HSC renewal in vitro. This project aims to overcome the key problem with existing in vitro systems, which lack the morphological and biochemical complexities of native HSC-niche. Since haematopoietic stem cells are the precursors to all blood cells, this project has the potential of engineering a high yield artificial ‘blood factory’, which will help save the lives of many thousands of people who rely on bone marrow transplants to treat life-threatening illness such as leukaemia.Read moreRead less
A highly sensitive and selective nano-engineered sensor for the online monitoring of mercury vapour emissions from harsh industrial processes. The Australian alumina and aluminium industries contribute over $11 billion export income annually. All refineries, except one, operate in rural areas and are the main economic drivers in these regions. In order to maintain the industry's commitment to reduce the environmental impact of its processes and remain economically sustainable, innovative technol ....A highly sensitive and selective nano-engineered sensor for the online monitoring of mercury vapour emissions from harsh industrial processes. The Australian alumina and aluminium industries contribute over $11 billion export income annually. All refineries, except one, operate in rural areas and are the main economic drivers in these regions. In order to maintain the industry's commitment to reduce the environmental impact of its processes and remain economically sustainable, innovative technologies are required to monitor mercury emissions. The aim of this project is to develop robust sensors, for online monitoring of mercury vapours, that operate under challenging industrial environments. This project will also provide excellent training for young researchers in established international industrial research groups, thereby meeting skill shortages in the Australian resource sector.Read moreRead less
Advanced three-dimensional fibrous structures for vascular graft applications. This project will combine advanced three-dimensional fabric structures, surface functionalisation and haemodynamic modelling to tackle critical issues in the design and manufacture of vascular graft materials. It will lead to the next generation of vascular grafts with much enhanced structural and biomedical performance.
Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes. With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing prob ....Using 3D printing technology to develop architecturally-controlled synthetic bone substitutes. With the ageing population, there is increasing demand for synthetic materials that can regenerate bone. However, purely synthetic bone-substitute biomaterials cannot regenerate large bone defects in weight-bearing conditions due to their fragility. This project aims to develop a customisable, biodegradable, biocompatible and mechanically strong and tough scaffold that overcomes this long-standing problem. The project aims to achieve this by applying an innovative combination of cutting-edge 3D printing technology, advanced computational modelling and design techniques to produce a next-generation bioceramic scaffold with optimised architecture. This approach aims also to enable the possibility of producing custom-made implants for individual requirements.Read moreRead less
High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significa ....High performance metal oxide inks for printable memory arrays . This project aims to develop next generation printable memory devices with low cost and excellent stability. The goal will be achieved by developing a new class of metal oxide nanomaterials based inks and large scale printing technology, through optimizing the synthesis, printing process and electrode configuration. The expected outcomes will be new electronic materials for a wide range of end uses in flexible electronics, significant advances in energy efficient data storage devices, and commercialisation of the technology to Australian industries.Read moreRead less
Fibre-sized energy generators and storage in multi-functional fabrics. This project proposes to do away with conventional batteries for powering portable or wearable devices by developing wearable fabrics capable of energy generation. The outcome will be a robust fabric with the capability of powering wearable or portable devices in the communications, health-care, sports and defence industries.
Self-powered active noise control via a nanofibre acoustoelectric converter. This project aims to investigate a new, active noise control system that can eliminate low frequency noise without the use of external electricity. This project will generate new knowledge about how to realise self-powering on active noise controllers using piezoelectric nanofibres as sound detector and power generator. Expected outcomes include an effective method to produce this novel noise controller and a systemic u ....Self-powered active noise control via a nanofibre acoustoelectric converter. This project aims to investigate a new, active noise control system that can eliminate low frequency noise without the use of external electricity. This project will generate new knowledge about how to realise self-powering on active noise controllers using piezoelectric nanofibres as sound detector and power generator. Expected outcomes include an effective method to produce this novel noise controller and a systemic understanding about materials, devices and performance. This will significantly benefit development of advanced noise controlling technology and products, benefiting industry and the environment.Read moreRead less
Engineering a silk fibroin based ear drum with optimum acoustic properties. This project will use new silk fibroin materials to develop ear drums with improved acoustic properties. This will lead to significant improvement in the quality of life of nearly 2.5 million people in Australia who are affected by hearing loss and further strengthen Australia's leading position in this area.
Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible ....Printable technologies for high security documents and consumer products. Printable technologies for high security documents and consumer products. This project aims to develop two next-generation printable security feature technologies to protect users from counterfeiting, which costs the world economy billions in lost revenue and undermines the security of citizens. First, it aims to enhance the security of banknotes by developing printable active device patches with energy harvesting flexible polymers as a power source and thin film graphene/polymer nanomaterial as an electrode/energy storage media. Second, it aims to design invisible carbon nanotube inks for optical authentication via near infrared activation. Both technologies are expected to thwart sophisticated counterfeits, particularly those supported by organised crime.Read moreRead less
Interface structures mediating load transfer between soft and hard tissues. This project aims to develop a novel technology platform to mediate load transfer between synthetic and biological materials with dissimilar mechanical properties, creating an effective interface mechanism. It will generate new knowledge in materials engineering by combining interdisciplinary expertise and state-of-the-art technologies in computational modelling, biomaterials, and additive manufacturing. Expected outcome ....Interface structures mediating load transfer between soft and hard tissues. This project aims to develop a novel technology platform to mediate load transfer between synthetic and biological materials with dissimilar mechanical properties, creating an effective interface mechanism. It will generate new knowledge in materials engineering by combining interdisciplinary expertise and state-of-the-art technologies in computational modelling, biomaterials, and additive manufacturing. Expected outcomes are high-tech ceramic structures optimized to interface effectively between synthetic soft tissues and natural hard tissues. This could ultimately benefit Australian industry engaged in developing next-generation synthetic orthopaedic solutions, providing a significant competitive advantage in an expanding global market.Read moreRead less