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Research Topic : TUMOUR MODELS
Scheme : Discovery Projects
Australian State/Territory : TAS
Australian State/Territory : SA
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  • Funded Activity

    Discovery Projects - Grant ID: DP180100520

    Funder
    Australian Research Council
    Funding Amount
    $303,931.00
    Summary
    Immunisation to protect against transmissible cancers in Tasmanian devils. This project aims to identify the immune escape mechanisms that the transmissible cancers, Devil Facial Tumour Disease (DFTD) use to avoid being killed by the immune system. Since the discovery of the second transmissible cancer (DFT2) mystery surrounds whether the devils immune system can respond to this cancer, hence this project will investigate the immune response to DFT2. The final aims are to develop a vaccine with .... Immunisation to protect against transmissible cancers in Tasmanian devils. This project aims to identify the immune escape mechanisms that the transmissible cancers, Devil Facial Tumour Disease (DFTD) use to avoid being killed by the immune system. Since the discovery of the second transmissible cancer (DFT2) mystery surrounds whether the devils immune system can respond to this cancer, hence this project will investigate the immune response to DFT2. The final aims are to develop a vaccine with the potential to protect healthy devils and cure devils with DFTD.
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    Funded Activity

    Discovery Projects - Grant ID: DP150101730

    Funder
    Australian Research Council
    Funding Amount
    $216,300.00
    Summary
    Building Central Asia: Linking the Growth of Asia to its Exhumation. The consumption of the Tethys Ocean and the associated collision of Gondwana-derived terranes with Eurasia resulted in the uplift of the highest mountain belt on Earth: the Himalayas. However, stresses from this collision zone propagated far into the Eurasian interior by reactivating faults and creating mountain belts along these fault zones. This project aims to map and model how and when fault (re)activation occurred by integ .... Building Central Asia: Linking the Growth of Asia to its Exhumation. The consumption of the Tethys Ocean and the associated collision of Gondwana-derived terranes with Eurasia resulted in the uplift of the highest mountain belt on Earth: the Himalayas. However, stresses from this collision zone propagated far into the Eurasian interior by reactivating faults and creating mountain belts along these fault zones. This project aims to map and model how and when fault (re)activation occurred by integrating multi-method thermochronological and structural data on major Meso-Cenozoic Central Asian fault systems. The resulting time-integrated tectonic model will aid in the understanding of the India-Eurasia collision, the building of the mountainous Central Asian landscape and its influence on the Asian climate.
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    Active Funded Activity

    Discovery Projects - Grant ID: DP240100325

    Funder
    Australian Research Council
    Funding Amount
    $384,217.00
    Summary
    Linking wave–sea ice feedbacks to rapid ice retreat. Antarctic sea ice extent has been in sharp decline since 2016, which is stressing the fragile Southern Ocean and Antarctic environments so vital to the global climate. This project aims to investigate a crucial candidate mechanism of sea ice loss by predicting rapid ice retreat in response to large Southern Ocean waves. New theory and modelling capabilities that account for wave–ice feedbacks will underpin the predictions, leveraging on recent .... Linking wave–sea ice feedbacks to rapid ice retreat. Antarctic sea ice extent has been in sharp decline since 2016, which is stressing the fragile Southern Ocean and Antarctic environments so vital to the global climate. This project aims to investigate a crucial candidate mechanism of sea ice loss by predicting rapid ice retreat in response to large Southern Ocean waves. New theory and modelling capabilities that account for wave–ice feedbacks will underpin the predictions, leveraging on recent research breakthroughs, including novel datasets derived from satellite and field observations. The outcomes are expected to quantify sea ice retreat due to ocean waves for the first time, with potentially major implications for coupled wave–sea ice modelling in climate studies.
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    Showing 1-3 of 3 Funded Activites

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