Snake envenoming is a neglected tropical disease and results in numerous deaths, psychological problems and economic burden. Antivenoms aren't readily available in resource poor countries. The CRE will investigate the effects of venom and antivenom to improve understanding of human envenoming. It will also develop tests for early diagnosis of envenoming and undertake clinical trials of antivenom. These studies will be translated back into clinical practice to improve treatment of snake bites.
A Randomised Controlled Trial To Examine The Effectiveness Of Oxytocin To Improve Treatment For Anorexia Nervosa
Funder
National Health and Medical Research Council
Funding Amount
$415,854.00
Summary
Anorexia nervosa (AN) is a major public health problem. Nutritional rehabilitation programs exist but can be costly and protracted, and patients struggle to engage with these demanding therapies. The purpose of this study is to determine the efficacy of oxytocin nasal spray to improve outcomes in patients with AN participating in a nutritional rehabilitation program using a randomized placebo-controlled design. If shown to be effective, this will have national and international significance.
Ketamine Therapy Among Patients With Treatment-resistant Depression: A Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,069,382.00
Summary
In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.
Frontotemporal Dementia And Motor Neurodegenerative Syndromes
Funder
National Health and Medical Research Council
Funding Amount
$17,069,580.00
Summary
Frontotemporal degeneration of the brain is a leading cause of morbidity due to a pathologically heterogeneous, rapidly-progressive group of disorders with behavioural, language and motor deficits. Our internationally recognized team will continue to develop the necessary tools and therapies to effectively diagnose, manage and treat these disorders. Our focus in this program is to understand the unusual genetics underpinning these disorders, and to fast track any potential treatments.
Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated i ....Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated industrial wastewater. The second part would be based on the study of a suitable depth filter medium for the treatment of partially treated household sewage water. This is designed to form part of an on-site household sewage water treatment and reuse system which is currently being developed.Read moreRead less
Restorative Justice for Victims and Serious Offenders. This project investigates how to reduce the human costs of serious crime through Restorative Justice (RJ) processes that can help victims recover from the trauma of serious crimes and hold offenders accountable for their actions. The project will (1) provide an independent and rigorous assessment of the RJ program for the industry partner, (2) contribute to an evidence-based national debate on policy responses to serious crimes through ident ....Restorative Justice for Victims and Serious Offenders. This project investigates how to reduce the human costs of serious crime through Restorative Justice (RJ) processes that can help victims recover from the trauma of serious crimes and hold offenders accountable for their actions. The project will (1) provide an independent and rigorous assessment of the RJ program for the industry partner, (2) contribute to an evidence-based national debate on policy responses to serious crimes through identifying the strengths and limitations of RJ and showing how RJ can be optimally practised to maximise benefits for all participants and the wider community, and (3) contribute significantly to the theory and practice of RJ, enhancing Australia's international reputation as a leader in this research area.Read moreRead less
Towards an effective practice model for youth detention. This project aims to examine the effectiveness of an innovative government program, which seeks to enhance the safety and rehabilitative culture of juvenile detention centres by increasing staff interpersonal skills through specialist training, coaching and supervision. The project is expected to identify best practice principles, allowing government departments to focus efforts on training and staff support to provide a higher quality wor ....Towards an effective practice model for youth detention. This project aims to examine the effectiveness of an innovative government program, which seeks to enhance the safety and rehabilitative culture of juvenile detention centres by increasing staff interpersonal skills through specialist training, coaching and supervision. The project is expected to identify best practice principles, allowing government departments to focus efforts on training and staff support to provide a higher quality work force. An evidence based framework will be developed in consultation with juvenile justice agencies across Australia. This will potentially improve outcomes for young people in custody and the wider community.Read moreRead less
A pilot study to demonstrate the use of 15N tracers for determining the flow of nitrogen through lower food webs. This project will have a significant impact on the way wetland wastewater treatment and reuse (WWTR) facilities are constructed in the future. Addressing the key biochemical issues to WWTR systems this study will facilitate improved construction design and management to optimise treatment performance. As National Priority One Area, sustainable water use and the efficiency of WWTR sys ....A pilot study to demonstrate the use of 15N tracers for determining the flow of nitrogen through lower food webs. This project will have a significant impact on the way wetland wastewater treatment and reuse (WWTR) facilities are constructed in the future. Addressing the key biochemical issues to WWTR systems this study will facilitate improved construction design and management to optimise treatment performance. As National Priority One Area, sustainable water use and the efficiency of WWTR systems is fundamental to our economic and social development. The results gleaned from this study will assist in the future design of WWTR systems that will be transferable outside the local study area and as such be of potential benefit both Nationally and internationally.Read moreRead less
The Intended and Unintended Impact of Policy for Adaptive Policy Management. The project aims to advance knowledge about the intended and unintended consequences of policy on health and well-being. It expects to innovate through new methods and novel data to integrate policy evaluation into the policy cycle in a timely fashion to prevent harm from occurring. It also leverages technology to track policy effects in real time. Expected outcomes of this project include new knowledge and enhanced pol ....The Intended and Unintended Impact of Policy for Adaptive Policy Management. The project aims to advance knowledge about the intended and unintended consequences of policy on health and well-being. It expects to innovate through new methods and novel data to integrate policy evaluation into the policy cycle in a timely fashion to prevent harm from occurring. It also leverages technology to track policy effects in real time. Expected outcomes of this project include new knowledge and enhanced policy infrastructure using new methods and interdisciplinary approaches. Significant benefits include improvements to: (1) policy management by government departments; (2) the health and wellbeing of the Australians they serve; (3) our Partners' capacity to consult governments on how technology can assist policy management. Read moreRead less
Positive life pathways for vulnerable adolescents: The role of a life management program approach. Young people in contact with the criminal justice system who have problematic use of drugs and alcohol often lack opportunities for social and economic participation in society and many continue offending into adulthood. This project aims to examine and analyse the short and longer term outcomes and pathways of such young people who participate in a Program for Adolescent Life Management compared w ....Positive life pathways for vulnerable adolescents: The role of a life management program approach. Young people in contact with the criminal justice system who have problematic use of drugs and alcohol often lack opportunities for social and economic participation in society and many continue offending into adulthood. This project aims to examine and analyse the short and longer term outcomes and pathways of such young people who participate in a Program for Adolescent Life Management compared with similar young people who have not completed such a program. The findings aim to directly inform policies and programs, including life management, drug and alcohol and other support programs to better address multiple needs among this vulnerable group.Read moreRead less