Snake envenoming is a neglected tropical disease and results in numerous deaths, psychological problems and economic burden. Antivenoms aren't readily available in resource poor countries. The CRE will investigate the effects of venom and antivenom to improve understanding of human envenoming. It will also develop tests for early diagnosis of envenoming and undertake clinical trials of antivenom. These studies will be translated back into clinical practice to improve treatment of snake bites.
A Randomised Controlled Trial To Examine The Effectiveness Of Oxytocin To Improve Treatment For Anorexia Nervosa
Funder
National Health and Medical Research Council
Funding Amount
$415,854.00
Summary
Anorexia nervosa (AN) is a major public health problem. Nutritional rehabilitation programs exist but can be costly and protracted, and patients struggle to engage with these demanding therapies. The purpose of this study is to determine the efficacy of oxytocin nasal spray to improve outcomes in patients with AN participating in a nutritional rehabilitation program using a randomized placebo-controlled design. If shown to be effective, this will have national and international significance.
Ketamine Therapy Among Patients With Treatment-resistant Depression: A Randomised, Double-blind, Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,069,382.00
Summary
In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.
Frontotemporal Dementia And Motor Neurodegenerative Syndromes
Funder
National Health and Medical Research Council
Funding Amount
$17,069,580.00
Summary
Frontotemporal degeneration of the brain is a leading cause of morbidity due to a pathologically heterogeneous, rapidly-progressive group of disorders with behavioural, language and motor deficits. Our internationally recognized team will continue to develop the necessary tools and therapies to effectively diagnose, manage and treat these disorders. Our focus in this program is to understand the unusual genetics underpinning these disorders, and to fast track any potential treatments.
Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated i ....Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated industrial wastewater. The second part would be based on the study of a suitable depth filter medium for the treatment of partially treated household sewage water. This is designed to form part of an on-site household sewage water treatment and reuse system which is currently being developed.Read moreRead less
Restorative Justice for Victims and Serious Offenders. This project investigates how to reduce the human costs of serious crime through Restorative Justice (RJ) processes that can help victims recover from the trauma of serious crimes and hold offenders accountable for their actions. The project will (1) provide an independent and rigorous assessment of the RJ program for the industry partner, (2) contribute to an evidence-based national debate on policy responses to serious crimes through ident ....Restorative Justice for Victims and Serious Offenders. This project investigates how to reduce the human costs of serious crime through Restorative Justice (RJ) processes that can help victims recover from the trauma of serious crimes and hold offenders accountable for their actions. The project will (1) provide an independent and rigorous assessment of the RJ program for the industry partner, (2) contribute to an evidence-based national debate on policy responses to serious crimes through identifying the strengths and limitations of RJ and showing how RJ can be optimally practised to maximise benefits for all participants and the wider community, and (3) contribute significantly to the theory and practice of RJ, enhancing Australia's international reputation as a leader in this research area.Read moreRead less
A pilot study to demonstrate the use of 15N tracers for determining the flow of nitrogen through lower food webs. This project will have a significant impact on the way wetland wastewater treatment and reuse (WWTR) facilities are constructed in the future. Addressing the key biochemical issues to WWTR systems this study will facilitate improved construction design and management to optimise treatment performance. As National Priority One Area, sustainable water use and the efficiency of WWTR sys ....A pilot study to demonstrate the use of 15N tracers for determining the flow of nitrogen through lower food webs. This project will have a significant impact on the way wetland wastewater treatment and reuse (WWTR) facilities are constructed in the future. Addressing the key biochemical issues to WWTR systems this study will facilitate improved construction design and management to optimise treatment performance. As National Priority One Area, sustainable water use and the efficiency of WWTR systems is fundamental to our economic and social development. The results gleaned from this study will assist in the future design of WWTR systems that will be transferable outside the local study area and as such be of potential benefit both Nationally and internationally.Read moreRead less
Positive life pathways for vulnerable adolescents: The role of a life management program approach. Young people in contact with the criminal justice system who have problematic use of drugs and alcohol often lack opportunities for social and economic participation in society and many continue offending into adulthood. This project aims to examine and analyse the short and longer term outcomes and pathways of such young people who participate in a Program for Adolescent Life Management compared w ....Positive life pathways for vulnerable adolescents: The role of a life management program approach. Young people in contact with the criminal justice system who have problematic use of drugs and alcohol often lack opportunities for social and economic participation in society and many continue offending into adulthood. This project aims to examine and analyse the short and longer term outcomes and pathways of such young people who participate in a Program for Adolescent Life Management compared with similar young people who have not completed such a program. The findings aim to directly inform policies and programs, including life management, drug and alcohol and other support programs to better address multiple needs among this vulnerable group.Read moreRead less
Using Health Economics To Strengthen Ties Between Evidence, Policy And Practice In Chronic Disease
Funder
National Health and Medical Research Council
Funding Amount
$1,925,648.00
Summary
There is a major shortage of researchers with health economics expertise in Australia. This grant will provide training and development for a team of health economists to research chronic diseases covering issues such as: What is the value for money from investment in different treatments? How do such diseases affect the economic circumstances of families? How do we ensure that strategies to address illness work in practice and can be sustained? How do these issues get put on the policy agenda?
Fate of micropollutants in water recycling: influence of dissolved organic matter. Access to safe drinking water is essential for the economic and social development of Australia. There is increasing interest in applying advanced water treatment processes, such as membrane filtration or ozonation, to treat secondary effluent to a potable standard. This project promotes improved organic pollutant removal and monitoring during advanced water treatment and will contribute to the National Research P ....Fate of micropollutants in water recycling: influence of dissolved organic matter. Access to safe drinking water is essential for the economic and social development of Australia. There is increasing interest in applying advanced water treatment processes, such as membrane filtration or ozonation, to treat secondary effluent to a potable standard. This project promotes improved organic pollutant removal and monitoring during advanced water treatment and will contribute to the National Research Priority goal, water - a critical resource, by providing the increased protection of receiving waters including rivers and seawater. Further, as very few studies consider the role of dissolved organic matter for organic pollutant fate in water reuse internationally, this project will help to advance Australia's position in science.Read moreRead less