Understanding and controlling the construction of molecular electronic and photovoltaic devices using nucleic acids. The efficient generation and use of energy is arguably the most pressing problem the world faces today. This project will enable the construction of molecular electronic and energy generation devices with increased efficiency, and will impact the fields of bio-organic chemistry and material science. Australia will benefit from the cheap and efficient energy produced by these new e ....Understanding and controlling the construction of molecular electronic and photovoltaic devices using nucleic acids. The efficient generation and use of energy is arguably the most pressing problem the world faces today. This project will enable the construction of molecular electronic and energy generation devices with increased efficiency, and will impact the fields of bio-organic chemistry and material science. Australia will benefit from the cheap and efficient energy produced by these new environmentally benign energy generation and transducing devices. A secondary benefit will arise when these devices are applied to medical diagnostics for early detection of diseases. Economic and environmental benefits for the Australian community and Australia's development as a knowledge-based economy will be the result.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100121
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
An analytical transmission electron microscope for the investigation of functional materials, earth processes and novel condensed matter. Sustainablity depends on the delivery of clean energy, pristine water and air, and the manufacture of consumer products with small environmental footprints. Modelling long-term impacts requires an understanding of the hydro-geological cycles. The technologies are well known—efficient electronics, fuel cells, lightweight composites, and so on—but delivery is ....An analytical transmission electron microscope for the investigation of functional materials, earth processes and novel condensed matter. Sustainablity depends on the delivery of clean energy, pristine water and air, and the manufacture of consumer products with small environmental footprints. Modelling long-term impacts requires an understanding of the hydro-geological cycles. The technologies are well known—efficient electronics, fuel cells, lightweight composites, and so on—but delivery is not straightforward. It is clear, however, that novel materials manipulated at fine scales will be key. Transmission electron microscopy (TEM) guides the development of sustainable technologies. The new TEM facility at ANU will accelerate current studies, by enhancing the materials research portfolio, and extending national and international collaborations in materials, geological and earth sciences.Read moreRead less
Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food proces ....Smart Nanocapsules for Efficient Cellular Delivery of Bioactive Peptide Drugs. This project will bring about practical benefits in terms of developing efficient therapeutic drug delivery systems, which has a market growth estimated to be ca. 23% p.a. in the world. The novel encapsulation technology developed in this project is not only desirable for biomolecules but also applicable for other functional materials and will find wide applications in a number of fields, such as chemical, food processing and cosmetic industries. Successful completion of the project can also strengthen our capacity to participate in new areas of research and positioning Australia at the forefront of bionanotechnology.Read moreRead less
Multifunctional biodegradable nanoparticles for enhanced DNA vaccine delivery. DNA vaccine, which shows better immunological and economic merits than conventional vaccines, suffers clinical failure due to the difficulty of delivering intact DNA molecules to relevant cells. This project seeks to develop smart polymer nanospheres to protect the DNA molecules from premature degradation in order to improve its efficacy.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100125
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
Advanced fluorescence imaging facility: from super high resolution to whole animal imaging. The establishment of this advanced fluorescence imaging facility will provide cutting-edge infrastructure to examine cells, pathogens and interactions between engineered drug delivery systems in both cells and whole animals. The facility will foster the development of new nanomedicines.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100163
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
Live Cell Super Resolution Imaging Facility. The recent convergence of nanoscience and biology heralds a new era for the development of new biotechnologies. Advances in this field are critically dependent on being able to explore and understand the interactions of nanomaterials with cells in their live, dynamic state. This proposal aims to establish a Live Cell Super Resolution Imaging Facility, which will enable dynamic nanomaterial–cell interactions to be interrogated. This facility will under ....Live Cell Super Resolution Imaging Facility. The recent convergence of nanoscience and biology heralds a new era for the development of new biotechnologies. Advances in this field are critically dependent on being able to explore and understand the interactions of nanomaterials with cells in their live, dynamic state. This proposal aims to establish a Live Cell Super Resolution Imaging Facility, which will enable dynamic nanomaterial–cell interactions to be interrogated. This facility will underpin leading research programs at The University of Melbourne, Monash University, RMIT, the Peter MacCallum Cancer Centre and the Bionics Institute, promoting synergies across the physical and biological sciences for generating new knowledge and advancing bio-nanoscience and technology.Read moreRead less
Bioprogramming the behaviour of nanoparticles in live cells by nanoscopy . The project aims to develop safer materials that are sustainably sourced from sweet corn, and investigate using advanced imaging technologies, how these materials are processed in biological systems, including human and plant cells. This project expects to generate new knowledge in the optimal design of materials that can be used safely and effectively in biological applications in medicine and in agriculture. Expected ou ....Bioprogramming the behaviour of nanoparticles in live cells by nanoscopy . The project aims to develop safer materials that are sustainably sourced from sweet corn, and investigate using advanced imaging technologies, how these materials are processed in biological systems, including human and plant cells. This project expects to generate new knowledge in the optimal design of materials that can be used safely and effectively in biological applications in medicine and in agriculture. Expected outcomes of this multidisciplinary project include a library of highly biocompatible nanomaterials and expanded knowledge on imaging technologies and structure-function relationship of nanomaterials in biological cells. This should provide significant benefits, such as improved crop yields and safer transfection agents.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100223
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
Advanced in-situ electron microscope facility for research in alloys, nanomaterials, functional materials, magnetic materials and minerals. This advanced in situ electron microscope facility will provide Australia with a new and critical capability to understand and design technologically important materials. It will enable advances in the areas of energy, environment, transport, construction and mining.
Characterisation and fabrication of nanophotonic devices based on multi-layer stacks. The aim of this proposal is to continue the existing collaborative project on fabrication and characterisation of nanophotonic devices based on the multi-layer stack method. The project will integrate the state-of-the-art techniques in the respective collaborating universities to fabricate a nano-probe which can produce an evanescent field approximately four orders of magnitude stronger than that under the conv ....Characterisation and fabrication of nanophotonic devices based on multi-layer stacks. The aim of this proposal is to continue the existing collaborative project on fabrication and characterisation of nanophotonic devices based on the multi-layer stack method. The project will integrate the state-of-the-art techniques in the respective collaborating universities to fabricate a nano-probe which can produce an evanescent field approximately four orders of magnitude stronger than that under the conventional condition. This novel probe provides a key to the successful fabrication of innovative nanophotonic devices including photonic transistors, photonic circuits, high-density data storage disks and drives, nano-motors and biochips, which underpin biotechnology, information technology and optical computing technology.Read moreRead less