Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561229
Funder
Australian Research Council
Funding Amount
$518,427.00
Summary
Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at V ....Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at Victoria University for the development of communication and endoscopic technology. The instrument design will allow multiple use of the lightsource and choice of specific imaging devices (microscopes) to ensure that applications in biocellular imaging, intravital microscopy and fiber optic design and imaging are individually optimised.Read moreRead less
Special Research Initiatives - Grant ID: SR0354622
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network ....Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the early embryo have major consequences for the development of individuals. The aim of this Network is to harness the resources of leading researchers from the previously distinct disciplines of developmental biology and developmental physiology to better understand developmental regulatory networks and how environmental factors impinge on them. The formation of such a Network is unique, timely and strategic in that it will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory ne ....ARC/NHMRC Research Network in Genes and Environment in Development. Interactions between the early environment and the genetic regulatory program of the developing organism have major consequences for the lifetime health of individuals. The primary objective of the Network in Genes and Environment in Development is to harness the resources of leading researchers from the currently distinct disciplines of developmental biology and developmental physiology to define key developmental regulatory networks and to address how environmental factors impinge on these regulatory networks. The formation of this National Research Network is unique, timely and strategic. It will generate new insights into the mechanisms by which events in early life determine the risk of adverse outcomes in perinatal and adult life.Read moreRead less
Engaging Students during the Early Years of Secondary School. This project aims to design, test and share sustainable strategies to support teachers and enable students from low socioeconomic communities to achieve success. The greatest decreases in students’ interest and effort occur when they transition into secondary school, with students from low socioeconomic communities at greatest risk of disengagement. What can teachers do to engage their students during this key life transition? This pr ....Engaging Students during the Early Years of Secondary School. This project aims to design, test and share sustainable strategies to support teachers and enable students from low socioeconomic communities to achieve success. The greatest decreases in students’ interest and effort occur when they transition into secondary school, with students from low socioeconomic communities at greatest risk of disengagement. What can teachers do to engage their students during this key life transition? This project plans to identify teacher behaviours that motivate students in their first year at secondary school. Using an experimental design with a representative sample of 150 teachers and 1500 students in low socioeconomic areas across three states, the project plans to test whether an online professional learning program for teachers can improve student engagement and achievement. This cost-effective and scalable intervention is designed for widespread dissemination to Australian teachers.Read moreRead less
The origins of electroreception and nocturnality in the earliest known jawed vertebrates and their bearing on vertebrate diversification. This project aims to discover primary new data to pinpoint the timing, anatomical origins and phylogenetic significance when two key sensory systems first appeared in modern vertebrates: electroreception and specialised nocturnal vision. Such abilities today allow high diversity of vertebrates to co-exist within the same geographical range, for example on trop ....The origins of electroreception and nocturnality in the earliest known jawed vertebrates and their bearing on vertebrate diversification. This project aims to discover primary new data to pinpoint the timing, anatomical origins and phylogenetic significance when two key sensory systems first appeared in modern vertebrates: electroreception and specialised nocturnal vision. Such abilities today allow high diversity of vertebrates to co-exist within the same geographical range, for example on tropical reefs or rainforest communities, through careful temporal niche partitioning where reliance on other sensory systems takes over from vision and olfaction as the principal method of prey detection. This project aims to elucidate how the modern fish diversity was shaped by such significant early evolutionary events.Read moreRead less
Novel Methods For Promoting Organ Development And Growth
Funder
National Health and Medical Research Council
Funding Amount
$390,203.00
Summary
A revolutionary new therapy for treatment of growth restricted fetuses and premature babies is being developed through the administration of Colony Stimulating Factor (CSF-1). We have evidence that CSF-1 therapy can promote kidneys and lungs to continue development and maturation after birth. This exciting new finding allows for the application of CSF-1 therapy for both the treatment of premature babies and unborn babies with kidney defects.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775673
Funder
Australian Research Council
Funding Amount
$1,200,000.00
Summary
A high throughput protein crystallization & imaging facility. Protein crystallography is an important field of research that enables us to understand the precise shape of proteins. The precise shape of a protein determines the function of a protein. This information is essential in understanding the physiological role of a protein and may be used for the development of therapeutics, where approrpiate. We aim to develop a high-throughput robotics system that will enable us to determine the sh ....A high throughput protein crystallization & imaging facility. Protein crystallography is an important field of research that enables us to understand the precise shape of proteins. The precise shape of a protein determines the function of a protein. This information is essential in understanding the physiological role of a protein and may be used for the development of therapeutics, where approrpiate. We aim to develop a high-throughput robotics system that will enable us to determine the shape of many proteins more rapidly, thereby greatly accelerating the pace of biomedical research.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100035
Funder
Australian Research Council
Funding Amount
$1,205,137.00
Summary
Founding an Australian Critical Zone Observatory Network. This proposal founds a new network of Australian Critical Zone Observatories. The network will fill essential knowledge gaps about interactions of under- and above-ground environmental processes and their responses to disturbance and change. These interactions determine the sustainability of food, clean water, mineral resources and Australian ecosystems, and cannot be studied with existing environmental infrastructure. The 5 foundation ....Founding an Australian Critical Zone Observatory Network. This proposal founds a new network of Australian Critical Zone Observatories. The network will fill essential knowledge gaps about interactions of under- and above-ground environmental processes and their responses to disturbance and change. These interactions determine the sustainability of food, clean water, mineral resources and Australian ecosystems, and cannot be studied with existing environmental infrastructure. The 5 foundational sites will host integrated monitoring equipment to observe stocks and fluxes of carbon, water, energy and mass across the “Critical Zone” – the vertical span from plant canopies to fresh bedrock. Joining a burgeoning international movement, the network will catalyse Critical Zone science in Australia.Read moreRead less
Quantitative metrics for determining aquifer ecosystem state. Clean groundwater comes from dirty surface water by way of biological purification. This project will develop quantitative ways to assess groundwater ecosystems to ensure the sustainable extraction of water and maintenance of these crucial ecosystems.
Understanding and Managing the Occupational Health Impacts on Investigators of Internet Child Exploitation. Through developing best practice models for managing vicarious trauma in investigators of Internet child exploitation, the project will result in enhanced job satisfaction and less burnout of workers, and reduced health costs for policing organisations. Thus the project addresses a serious occupational health issue and contributes to the goal of promoting and maintaining good health. Furth ....Understanding and Managing the Occupational Health Impacts on Investigators of Internet Child Exploitation. Through developing best practice models for managing vicarious trauma in investigators of Internet child exploitation, the project will result in enhanced job satisfaction and less burnout of workers, and reduced health costs for policing organisations. Thus the project addresses a serious occupational health issue and contributes to the goal of promoting and maintaining good health. Further, by better managing the occupational health of investigators, the project will enhance the capacity of police organisations to deliver on their mission of investigating and preventing Internet child exploitation. This in turn contributes to the reduced consumption of Internet child exploitation and the associated traumatisation of abused victims. Read moreRead less