From insects to robots: how brains make predictions and ignore distractions. This project aims to address fundamental questions in neuroscience and to integrate this biological understanding with the development of leading-edge robotics. Whether a human catching a ball or a dragonfly feeding in a swarm, brains have the remarkable ability to predict the future location of moving targets. The brain predicts in the presence of distractions and even if the target disappears, for example, when hidden ....From insects to robots: how brains make predictions and ignore distractions. This project aims to address fundamental questions in neuroscience and to integrate this biological understanding with the development of leading-edge robotics. Whether a human catching a ball or a dragonfly feeding in a swarm, brains have the remarkable ability to predict the future location of moving targets. The brain predicts in the presence of distractions and even if the target disappears, for example, when hidden behind another object. This project will investigate how brains use both environmental and internal information to select a target and predict its future location. By implementing bio-inspired computations in hardware, this project aims to provide significant benefits such as improving autonomous systems for defence, health and transportation.Read moreRead less
Next-generation computational models to understand human joints . This project aims to investigate human joint systems through combining state-of-the-art imaging and high-fidelity biomechanical models. The methods developed in this project are expected to generate new ways of studying the dynamic response of musculoskeletal tissues to activity, including how musculoskeletal physiology can adapt to biomechanical stimuli. Expected outcomes include establishing a non-invasive method for characteris ....Next-generation computational models to understand human joints . This project aims to investigate human joint systems through combining state-of-the-art imaging and high-fidelity biomechanical models. The methods developed in this project are expected to generate new ways of studying the dynamic response of musculoskeletal tissues to activity, including how musculoskeletal physiology can adapt to biomechanical stimuli. Expected outcomes include establishing a non-invasive method for characterising whole joint systems. This project will provide significant knowledge gain on the biomechanical regulation of human joints across form, function, dynamics and loading which may help across many facets of society to guide physical activity choices.Read moreRead less
Resolving the impact of pressure on hot and low-oxygen combustion. Despite the important role of renewable energy sources, combustion will remain essential for transportation into the foreseeable future. This project aims to investigate flames burning in a hot and low-oxygen environment. The objective is to better understand how these conditions could be applied to gas turbines. This project expects to generate new knowledge to enable a reduction in emissions, improvement in efficiency and incre ....Resolving the impact of pressure on hot and low-oxygen combustion. Despite the important role of renewable energy sources, combustion will remain essential for transportation into the foreseeable future. This project aims to investigate flames burning in a hot and low-oxygen environment. The objective is to better understand how these conditions could be applied to gas turbines. This project expects to generate new knowledge to enable a reduction in emissions, improvement in efficiency and increase in power output. Expected outcomes of this project include improved understanding of the governing physics to enable development of design tools for next-generation engines. This should provide significant benefits, such as reduced reliance on fossil fuels and a critical reduction in greenhouse gas emissions.Read moreRead less
Examining the links between obesity and insulin resistance. Obesity prevalence is rapidly increasing in Australia and contributes to the onset of many chronic diseases, such as diabetes, heart disease and cancer. This project will examine how obesity contributes to disease risk and how modifying nutrient delivery and other interventions that protect from cellular stress reduces these risks.
A kinematically and micromechanically enriched constitutive modelling framework for failure of geomaterials. Failure at large scale such as slopes, embankments, and underground mining is fatal in terms of human lives and property loss. This project aims to develop a new methodology to connect micro-mechanisms that trigger and govern failure with the behaviour at much larger scales. In particular it will allow building constitutive models directly from micro-scale mechanisms, while possessing the ....A kinematically and micromechanically enriched constitutive modelling framework for failure of geomaterials. Failure at large scale such as slopes, embankments, and underground mining is fatal in terms of human lives and property loss. This project aims to develop a new methodology to connect micro-mechanisms that trigger and govern failure with the behaviour at much larger scales. In particular it will allow building constitutive models directly from micro-scale mechanisms, while possessing the capability to span the spatial scales. It will also transform the understanding of material property scaling into a predictive tool for engineering analysis, helping to obtain more cost effective designs with greater confidence in safety.Read moreRead less
Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biologic ....Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biological environments. The expected outcome is to generate new material design rules to facilitate wireless neuromodulation technologies in biomedical engineering. The project will position Australia as a leader in bionic devices by creating a new 3D bioprinting hub for low-cost fabrication of bioelectronic systems.Read moreRead less
Efficient Management of Things for the Future World Wide Web. The future World Wide Web will connect billions of physical objects, which will offer exciting capabilities to change the world and improve the quality of human lives, just as what the Web has done in the past 20 years. Effectively and efficiently managing things is one inevitable challenge in this new era and is much more complicated than managing traditional Web documents. This project aims to focus on this key problem and develop n ....Efficient Management of Things for the Future World Wide Web. The future World Wide Web will connect billions of physical objects, which will offer exciting capabilities to change the world and improve the quality of human lives, just as what the Web has done in the past 20 years. Effectively and efficiently managing things is one inevitable challenge in this new era and is much more complicated than managing traditional Web documents. This project aims to focus on this key problem and develop novel techniques for linking resource-constrained things to the Web, searching them using a new search engine, as well as discovering latent relationships among things for advanced management tasks such as things recommendation and composition.Read moreRead less
Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise ....Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise therapies and diagnostic techniques for promoting hip strength. The project will contribute to the engineering of biological tissue and the development of high-strength and light-weight bio-inspired materials.Read moreRead less
Advanced biosensing in the terahertz (THz) sub-wavelength regime. This project will build on Australian excellence in photonics, exploiting the advanced use of T-rays for sensing of biological substances such as proteins and DNA. For the first time, this will enable contactless automated sensing for high-speed medical screening of diseases, a critical step toward the ultimate vision of customised medicine.
Plasma touches life: advancing plasma technologies for the life sciences. The aim of this project is to develop a mechanistic understanding of how electrically excited gas (plasma) jets deliver reactive oxygen and nitrogen species into tissue, ensuring safety and precision in their use to combat disease. Overcoming barriers in delivery is intended to help realise the full potential of plasma in the life sciences. The project is expected to generate new knowledge across physics, chemistry and bio ....Plasma touches life: advancing plasma technologies for the life sciences. The aim of this project is to develop a mechanistic understanding of how electrically excited gas (plasma) jets deliver reactive oxygen and nitrogen species into tissue, ensuring safety and precision in their use to combat disease. Overcoming barriers in delivery is intended to help realise the full potential of plasma in the life sciences. The project is expected to generate new knowledge across physics, chemistry and biology, leading to new approaches for the future development of plasma technologies. This should provide significant benefits by expanding the human capacity of research in plasma, and in growing the advanced manufacturing of plasma devices for future applications in engineering, biology and health.Read moreRead less