Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561104
Funder
Australian Research Council
Funding Amount
$402,128.00
Summary
A 10 Gbit/s Fibre Optic link to the Mt Pleasant and Mt Canopus Observatories. A 10 gigabit per second fibre optic link to the Mt Pleasant and Mt Canopus observatories will enable a wide range of new and exciting research opportunities. Very long baseline interferometry (VLBI) allows imaging of distant astronomical objects with much higher resolution than any other technique. The proposed fibre optic link will revolutionise Australia's VLBI capability, giving it the world's most sensitive array, ....A 10 Gbit/s Fibre Optic link to the Mt Pleasant and Mt Canopus Observatories. A 10 gigabit per second fibre optic link to the Mt Pleasant and Mt Canopus observatories will enable a wide range of new and exciting research opportunities. Very long baseline interferometry (VLBI) allows imaging of distant astronomical objects with much higher resolution than any other technique. The proposed fibre optic link will revolutionise Australia's VLBI capability, giving it the world's most sensitive array, with enhanced reliability and faster access to results for researchers. This project will greatly facilitate studies of astrophysical processes in Galactic and extra-galactic environments as well as precision measurements of the Earth's crustal dynamics.Read moreRead less
Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS rese ....Identifying genes that influence clinical course and susceptibility in multiple sclerosis. This project aims to identify the genetic basis of multiple sclerosis (MS), the most common neurologic disease in young Australian adults. MS urgently needs research to identify predisposition, aid early diagnosis and provide bona fide molecular targets for new therapies. This will benefit people with MS and those susceptible to it. Crucial new knowledge identified will benefit other major areas of MS research including epidemiology, immunology and neurobiology. Collaboration of 8 major Australian institutions is also important for this project and future studies. The team will have access to a new national MS GeneBank (platform) with samples from 2240 patients that should generate findings important to world-wide MS genetic knowledge.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100183
Funder
Australian Research Council
Funding Amount
$950,000.00
Summary
Protein Quantitation Centre of South Australia renewal for Systems Biology. This application aims to renew Mass Spectrometry (MS) instrumentation to characterise and quantify Biomolecules towards a better understanding of biological processes. UniSA, Uni Adelaide, Flinders have established the Protein Quantitation Centre of South Australia (PQCSA) in 2013 through an ARC LIEF lead by CI Hoffmann and this application will renew and expand MS capacity towards metabolites, glycans and lipids. This ....Protein Quantitation Centre of South Australia renewal for Systems Biology. This application aims to renew Mass Spectrometry (MS) instrumentation to characterise and quantify Biomolecules towards a better understanding of biological processes. UniSA, Uni Adelaide, Flinders have established the Protein Quantitation Centre of South Australia (PQCSA) in 2013 through an ARC LIEF lead by CI Hoffmann and this application will renew and expand MS capacity towards metabolites, glycans and lipids. This will enable researchers in South Australia to work towards a full understanding of biological processes and towards expanding their knowledge to Systems Biology. Expected outcome of the projects are multiple interdisciplinary collaborations between the CI's and should provide significant benefits in research outputs.Read moreRead less
Special Research Initiatives - Grant ID: SR1101002
Funder
Australian Research Council
Funding Amount
$21,000,000.00
Summary
Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and ....Stem Cells Australia. Despite progress in stem cell research, scientists do not understand how stem cells “decide” what to become. Stem Cells Australia will draw upon strengths within Australia’s premier stem cell research universities and institutes. This collaboration between leading bioengineering, nanotechnology, stem cell and advanced molecular analysis experts, will fast-track efforts to deliver a fundamental understanding of the mechanisms of stem cell regulation and differentiation, and the ability to control and influence this process. Stem Cells Australia will deliver new methods for stem cell propagation and manipulation, new translational technologies for therapeutic applications, and will prepare Australia’s future stem cell scientific leaders.Read moreRead less
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less
Social acceptability of forest management options: Landscape level visualisation and evaluation. Sustainable forest policy requires social acceptance. Prior research has investigated relative acceptability of options at a forest stand level. However, we have insufficient understanding of public acceptance of forest management systems implemented across the wider landscape. Only detailed knowledge of public reaction to social, environmental and economic impacts and the trade-offs involved can red ....Social acceptability of forest management options: Landscape level visualisation and evaluation. Sustainable forest policy requires social acceptance. Prior research has investigated relative acceptability of options at a forest stand level. However, we have insufficient understanding of public acceptance of forest management systems implemented across the wider landscape. Only detailed knowledge of public reaction to social, environmental and economic impacts and the trade-offs involved can reduce the divisive nature of the forest management debate. This project will use interactive, still and animated computer representations of landscapes to examine social acceptability of alternatives to clearfell harvesting. This knowledge will be integrated with biophysical data to improve management of forested landscapes.Read moreRead less
Program evaluation of the osteoarthritis awareness hub. Persons with osteoarthritis generally have poor knowledge about their disease and its appropriate management. The aim of this project is to evaluate whether improved knowledge, and management decisions of persons with osteoarthritis, can ultimately lead to improved health outcomes.
Acceptability of Forest Harvesting Systems. Fierce public debate over forest management has prompted forest agencies to develop and test alternative harvesting systems. This project will examine community response to these harvesting and regeneration options. It will avoid the biases of existing research by developing an interactive simulation of the forest environment that will allow participants to view visual, ecological and economic outcomes of harvest options, as well as changes over time ....Acceptability of Forest Harvesting Systems. Fierce public debate over forest management has prompted forest agencies to develop and test alternative harvesting systems. This project will examine community response to these harvesting and regeneration options. It will avoid the biases of existing research by developing an interactive simulation of the forest environment that will allow participants to view visual, ecological and economic outcomes of harvest options, as well as changes over time as forest regenerates. Public judgements of the acceptability of harvesting options will be integrated with the outcomes of related biophysical studies to identify socially and ecologically sustainable management options for Australian native forests.Read moreRead less
ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environme ....ARC Research Network in Enterprise Information Infrastructure. EII targets consolidated research towards the comprehensive development & establishment of advanced information infrastructures. Its prime purpose is to provide a forum for intellectual exchange by diverse yet complementary research groups, to address the fundamental research problems faced by scientific & business communities when dealing with deployment of information technology to globally distributed, and data intensive environments. EII will address 3 tightly coupled research themes: Ability to interoperate across existing heterogenous platforms & applications; Efficient processing of very large data sets; Technology adoption & impact. Generic results will be applicable to e-science and large business information systems installations.Read moreRead less