High-Performance Polymer Composites for Electrical Discharging. This project aims to address the problem of electrostatic discharge by developing new industry-compatible processing techniques and taking advantage of the synergy between graphene and carbon nanotubes and fibres. Electrostatic discharge due to accumulation of static electricity is a significant problem for lightweight polymer composites used in hazard environments, such as pumps for underground mining, oil and gas storage and satel ....High-Performance Polymer Composites for Electrical Discharging. This project aims to address the problem of electrostatic discharge by developing new industry-compatible processing techniques and taking advantage of the synergy between graphene and carbon nanotubes and fibres. Electrostatic discharge due to accumulation of static electricity is a significant problem for lightweight polymer composites used in hazard environments, such as pumps for underground mining, oil and gas storage and satellites. The outcomes will potentially transform the current manufacturing practice of anti-static composites for industry applications including mining, energy, space and agriculture. Read moreRead less
Microbial junk food: developing synthetic platforms for plastic degradation. This project aims to establish the genetic basis of polyethelene biodegradation (PED) by microbes from the gut microbiome of plastic-eating caterpillars. It will transform the active microbial PED genes into carefully designed synthetic microbes for efficient, safe and large-scale PED. The project will combine innovative functional microbial genetic tools and synthetic biology techniques with solid biochemistry and bioi ....Microbial junk food: developing synthetic platforms for plastic degradation. This project aims to establish the genetic basis of polyethelene biodegradation (PED) by microbes from the gut microbiome of plastic-eating caterpillars. It will transform the active microbial PED genes into carefully designed synthetic microbes for efficient, safe and large-scale PED. The project will combine innovative functional microbial genetic tools and synthetic biology techniques with solid biochemistry and bioinformatics to produce translatable synthetic platforms containing key genes optimised for efficient PE waste removal. The outcomes will have the potential to transform the relative ineffective and expensive current methods for PE disposal into flexible, cost-effective and sustainable solutions applicable to multiple sectors.Read moreRead less
Sculpting a masterpiece: synthesis and evolution of minimal yeast genomes. This project aims to better understand genome complexity by engineering minimal yeast genomes that have fewer genes, and are therefore easier to characterise and engineer. Yeast is a model organism and industrial food, fuel, and chemical producer. This project expects to increase our basic understanding of yeast genomes, and develop new tools for engineering whole genomes. Expected outcomes of this project include the eng ....Sculpting a masterpiece: synthesis and evolution of minimal yeast genomes. This project aims to better understand genome complexity by engineering minimal yeast genomes that have fewer genes, and are therefore easier to characterise and engineer. Yeast is a model organism and industrial food, fuel, and chemical producer. This project expects to increase our basic understanding of yeast genomes, and develop new tools for engineering whole genomes. Expected outcomes of this project include the engineering and characterisation of the world's first minimal yeast genome, and the development of novel industrial yeast strains. This will provide significant benefits for both fundamental genetics and biochemistry research, and the industrial use of yeast for bio-manufacturing of sustainable foods, fuels, and chemicals.Read moreRead less
Flipping the mattress: infinite polyurethane recycling by synthetic biology. Australia is covered in billions of tonnes of plastic and yet <10% is recycled today. Polyurethane (PU) is ubiquitous in our everyday lives, from lacquer coatings to elastane clothing to durable foam padding in car seats, cushions and mattresses. Currently, there are few avenues for PU recycling and much ends up in landfill e.g., a single mattress produces 15-20kg of PU foam waste. Luckily, biodegradation of PU can occu ....Flipping the mattress: infinite polyurethane recycling by synthetic biology. Australia is covered in billions of tonnes of plastic and yet <10% is recycled today. Polyurethane (PU) is ubiquitous in our everyday lives, from lacquer coatings to elastane clothing to durable foam padding in car seats, cushions and mattresses. Currently, there are few avenues for PU recycling and much ends up in landfill e.g., a single mattress produces 15-20kg of PU foam waste. Luckily, biodegradation of PU can occur naturally via various microbial means and from insects, like Galleria mellonella larvae. The overall aim of this research project is to understand plastic biodegradation and translate nature’s solutions into flexible and efficient synthetic enzyme technologies that can sustainably recycle commonly used PU foams. Read moreRead less
Advanced Materials from Automated Synthesis of Sequence-Defined Polymers. The project aims to develop industrially scalable and environmentally friendly methods for synthesis of sequence-defined multiblock copolymers (polymer chains containing segments of different polymer types) using automated synthesis methods. The materials to be explored will be largely based on renewable biomass-derived monomeric building blocks. Such polymers are able to undergo microphase separation into spatially period ....Advanced Materials from Automated Synthesis of Sequence-Defined Polymers. The project aims to develop industrially scalable and environmentally friendly methods for synthesis of sequence-defined multiblock copolymers (polymer chains containing segments of different polymer types) using automated synthesis methods. The materials to be explored will be largely based on renewable biomass-derived monomeric building blocks. Such polymers are able to undergo microphase separation into spatially periodic compositional patterns, thereby providing access to a vast range of nano-engineered materials. This would enable design and synthesis of new advanced materials, making use of renewable resources and supporting the circular economy, with diverse potential applications ranging from nanomedicine to materials science.Read moreRead less
Lightweight Photovoltaic Modules for Low-Load Capacity Building Roofs. This project aims to develop lightweight and reliable high efficiency photovoltaic modules that expand solar energy installations onto low-load capacity building roofs. New lightweight materials will be developed for packaging with multi-functionalities such as fast heat dissipation. This project will produce economical prototypes and enable and
facilitate cost reduction of crystalline silicon photovoltaic module installation ....Lightweight Photovoltaic Modules for Low-Load Capacity Building Roofs. This project aims to develop lightweight and reliable high efficiency photovoltaic modules that expand solar energy installations onto low-load capacity building roofs. New lightweight materials will be developed for packaging with multi-functionalities such as fast heat dissipation. This project will produce economical prototypes and enable and
facilitate cost reduction of crystalline silicon photovoltaic module installations on lightweight buildings, overcoming current constraints of heavy glass modules and making more solar energy exploited in both Australia’s urban and rural areas. This will get steps closer to zero emission buildings, by providing renewable energy alternative to conventional fossil fuel-based power generation.Read moreRead less
Orthogonal Sensing Strategies for Soft Sensors to Discern Multiple Stimuli . The project seeks to create new orthogonal sensing technologies that enable a single soft sensor to detect multiple mechanical and thermal stimuli, overcoming the challenge of cross-talk between stimuli. The project expects to generate new knowledge of orthogonal sensing mechanisms and the effects of microstructure designs. The expected outcomes include novel soft sensors capable of accurately detecting pressure, stretc ....Orthogonal Sensing Strategies for Soft Sensors to Discern Multiple Stimuli . The project seeks to create new orthogonal sensing technologies that enable a single soft sensor to detect multiple mechanical and thermal stimuli, overcoming the challenge of cross-talk between stimuli. The project expects to generate new knowledge of orthogonal sensing mechanisms and the effects of microstructure designs. The expected outcomes include novel soft sensors capable of accurately detecting pressure, stretch, shear, and temperature simultaneously. The new technologies are expected to support Australian companies in developing, producing and exporting sensors for soft robots and wearable devices for health monitoring, an area recognized as a key priority by the Federal Government’s Industry Growth Centres.Read moreRead less
From trash to treasure: engineering waste carbon utilisation in yeast. This project aims to engineer yeast to convert carbon dioxide- and methane-derived methanol into sustainable chemicals, foods, and pharmaceuticals. This project expects to generate new design principles for methanol metabolism by using the innovative approach of laboratory evolution along with state-of-the-art bio-engineering capabilities at Macquarie University and The University of Queensland. Expected outcomes of this proj ....From trash to treasure: engineering waste carbon utilisation in yeast. This project aims to engineer yeast to convert carbon dioxide- and methane-derived methanol into sustainable chemicals, foods, and pharmaceuticals. This project expects to generate new design principles for methanol metabolism by using the innovative approach of laboratory evolution along with state-of-the-art bio-engineering capabilities at Macquarie University and The University of Queensland. Expected outcomes of this project include new manufacturing processes for chemicals and foods, discovery of novel metabolism in yeast, and enhanced collaboration between Australia, Denmark, and the United States. This Project will provide benefits through sustainable bio-manufacturing, new economic activity, and reduced greenhouse gas emissions.Read moreRead less
Remodelling encapsulin nanocages to help enhance plant carbon fixation. Nature has evolved mechanisms in microbial systems to improve photosynthetic efficiency by saturating the enzyme Rubisco with carbon dioxide. These carbon concentrating mechanisms are genetically complex, precluding successful introduction into crops. Our simpler approach is to use encapsulins, a new source of robust bacterial pore-containing nanocages made from a single gene. This project will optimise the development of sy ....Remodelling encapsulin nanocages to help enhance plant carbon fixation. Nature has evolved mechanisms in microbial systems to improve photosynthetic efficiency by saturating the enzyme Rubisco with carbon dioxide. These carbon concentrating mechanisms are genetically complex, precluding successful introduction into crops. Our simpler approach is to use encapsulins, a new source of robust bacterial pore-containing nanocages made from a single gene. This project will optimise the development of synthetic encapsulin-Rubisco carbon-fixing nanoreactors and transform them into leaf chloroplasts to test their impact on plant photosynthesis and growth. Our genetically simpler solution will aid ongoing global efforts to deliver overdue step change improvements in agricultural productivity.Read moreRead less