Molecular evolution of a model oligomeric enzyme from bacterial extremophiles. The national benefits of this research program include insight into the sustainability of marine microorganisms that play an important role in Australia's diverse ecosystem, the development and applications of frontier technologies including high-performance computing on the world's largest supercomputer facility for life science research, and knowledge impacting on the discovery of novel antibiotics that target patho ....Molecular evolution of a model oligomeric enzyme from bacterial extremophiles. The national benefits of this research program include insight into the sustainability of marine microorganisms that play an important role in Australia's diverse ecosystem, the development and applications of frontier technologies including high-performance computing on the world's largest supercomputer facility for life science research, and knowledge impacting on the discovery of novel antibiotics that target pathogenic bacteria, like Golden Staph. This program will also train several young Australians in highly sought after skills, including bacteriology, biophysics, enzymology, molecular biology, molecular modelling, protein chemistry and structural biology. Read moreRead less
Stepping-Stones or Barrier: The Movement and Impact of People throughout the Far Eastern Pacific Islands. The vast ocean of the far eastern Pacific divides two great migratory peoples, the Amerindians and Polynesians. Whether or not members of either group overcame this barrier remains one of the greatest uncertainties in Pacific prehistory. We focus on the remote islands of the far eastern Pacific Ocean and combine fine-resolution archaeology, palaeoecology, and dating techniques to determine t ....Stepping-Stones or Barrier: The Movement and Impact of People throughout the Far Eastern Pacific Islands. The vast ocean of the far eastern Pacific divides two great migratory peoples, the Amerindians and Polynesians. Whether or not members of either group overcame this barrier remains one of the greatest uncertainties in Pacific prehistory. We focus on the remote islands of the far eastern Pacific Ocean and combine fine-resolution archaeology, palaeoecology, and dating techniques to determine the antiquity and nature of occupation on these islands. Their role as stepping-stones for human migration and material exchange will be determined and the notion of these islands as pristine and unspoilt at the time of European discovery will be challenged.Read moreRead less
Influence of Marine Protected Areas on ecosystem resilience and ecological processes. Australia is implementing a national representative system of marine protected areas (MPAs). The aims of the MPAs include ensuring ecological viability, maintaining ecological processes, and protecting biodiversity. The ability of MPAs to achieve these aims, however, is based largely on theory rather than empirical evidence. Implementation of MPAs is often controversial as it may cause economic hardship to comm ....Influence of Marine Protected Areas on ecosystem resilience and ecological processes. Australia is implementing a national representative system of marine protected areas (MPAs). The aims of the MPAs include ensuring ecological viability, maintaining ecological processes, and protecting biodiversity. The ability of MPAs to achieve these aims, however, is based largely on theory rather than empirical evidence. Implementation of MPAs is often controversial as it may cause economic hardship to communities dependent on fishing. Our project will benefit environmental managers by determining if and how MPAs influence biodiversity, ecological processes, and ecosystem services and resilience. It will benefit the wider community by providing the rigorous scientific evidence in favour of MPAs that is demanded by stakeholders.Read moreRead less
BIOPROSPECTING FOR NOVEL EXTRACTANTS TO SEPARATE NICKEL AND COBALT. Cobalt (Co) is a common 'guest' element in nickel (Ni) ore. Separating these metals is crucial to the production of high purity of Ni and Co, valuable metals for the Australian economy. Currently, processing of Ni-ore relies on energy-intensive dissolution followed by separation of Co from Ni using expensive synthetic chelators. A few rare Ni- and Co-accumulating plants however, have evolved biochemical mechanisms to distingu ....BIOPROSPECTING FOR NOVEL EXTRACTANTS TO SEPARATE NICKEL AND COBALT. Cobalt (Co) is a common 'guest' element in nickel (Ni) ore. Separating these metals is crucial to the production of high purity of Ni and Co, valuable metals for the Australian economy. Currently, processing of Ni-ore relies on energy-intensive dissolution followed by separation of Co from Ni using expensive synthetic chelators. A few rare Ni- and Co-accumulating plants however, have evolved biochemical mechanisms to distinguish between Ni and Co. We propose the first determination of the mechanisms of Ni/Co discrimination in these unusual plants, effectively biosprospecting for novel commercial extractants to separate Ni and Co. Read moreRead less
Drought and Salinity Tolerance in Metal Hyperaccumulating Plants: A Functional Role for the Metals? A few plant species can ?hyperaccumulate? metal ions to 100-1000 times the concentrations seen in ?normal? plants. Just why these plants have evolved such an extreme response to metalliferous soils remains an enigma. Many of the hyperaccumulators so far described are endemic to xeric environments, or saline soils prone to rapid drying. We hypothesize that the metals might act as osmotica, enha ....Drought and Salinity Tolerance in Metal Hyperaccumulating Plants: A Functional Role for the Metals? A few plant species can ?hyperaccumulate? metal ions to 100-1000 times the concentrations seen in ?normal? plants. Just why these plants have evolved such an extreme response to metalliferous soils remains an enigma. Many of the hyperaccumulators so far described are endemic to xeric environments, or saline soils prone to rapid drying. We hypothesize that the metals might act as osmotica, enhancing plant survival during water stress. This will be tested for Australian native and non-native hyperaccumulator plants. The study will clarify our understanding of the evolutionary significance of hyperaccumulation, and has important applications for extracting metals from contaminated soils.Read moreRead less
How does soil fertility affect jarrah forest rehabilitation after mining? This project will examine the effect of fertiliser additions on the species composition and functional diversity of jarrah forest that develops after bauxite-mining. It is directly relevant to the achievement of the sustainable use of natural resources in Australia. Expected outcomes are best-practice management guidelines regarding the amount of fertiliser that results in the most effective achievement of completion cri ....How does soil fertility affect jarrah forest rehabilitation after mining? This project will examine the effect of fertiliser additions on the species composition and functional diversity of jarrah forest that develops after bauxite-mining. It is directly relevant to the achievement of the sustainable use of natural resources in Australia. Expected outcomes are best-practice management guidelines regarding the amount of fertiliser that results in the most effective achievement of completion criteria, and also an improved understanding of the consequences of fertiliser application on the biodiversity (plants and soil biota) and ecosystem function of rehabilitated forest ecosystems. Read moreRead less
Understanding and managing resistance to the amphibian chytrid fungus Batrachochytrium dendrobatidis in Australian tropical rainforest frogs. The fungal disease chytridiomycosis can infect at least 48 Australian native frog species and is listed as a threatening process under the federal Environment Protection and Biodiversity Conservation Act. It caused catastrophic declines in 12 frog species in Queensland between 1979 and 1994, and is probably responsible for continuing declines in many more ....Understanding and managing resistance to the amphibian chytrid fungus Batrachochytrium dendrobatidis in Australian tropical rainforest frogs. The fungal disease chytridiomycosis can infect at least 48 Australian native frog species and is listed as a threatening process under the federal Environment Protection and Biodiversity Conservation Act. It caused catastrophic declines in 12 frog species in Queensland between 1979 and 1994, and is probably responsible for continuing declines in many more species in most states. A few species and populations have recovered following declines, indicating that they have increased their resistance to the disease. Understanding these increases in resistance should allow us to develop ways to control the disease in other species, helping to protect Australia against this invasive and highly destructive disease.Read moreRead less
Toad vs Toad: Innovative approaches to understand and control an invasive species. Understanding the ecology of an invasive pest species can be a powerful tool for developing control methods. Cane toads pose a major threat to Australian native species, and are spreading increasingly rapidly through the Australian tropics. Unfortunately, we still know very little about the biology of invasion-front populations of toads. This project will provide that understanding, and will explore new ideas a ....Toad vs Toad: Innovative approaches to understand and control an invasive species. Understanding the ecology of an invasive pest species can be a powerful tool for developing control methods. Cane toads pose a major threat to Australian native species, and are spreading increasingly rapidly through the Australian tropics. Unfortunately, we still know very little about the biology of invasion-front populations of toads. This project will provide that understanding, and will explore new ideas about ways to control toad populations. For example, if we can reduce the survival of feral animals by increasing the intensity of competition within their own popualtions rather than relying on effects of other species, we may be able to use the toads to control their own populations.Read moreRead less
Predicting the ecological impact of cane toads on native fauna of northwestern Australia. At current rates of spread, cane toads will invade the Kimberley region of northwestern Australia within a few years. We urgently need to be able to predict which native species will be at risk from toads, and which will be relatively unaffected either because they are not killed by toads, or because they can rapidly learn, or evolve, in ways that reduce this impact and thus allow population recovery. We ....Predicting the ecological impact of cane toads on native fauna of northwestern Australia. At current rates of spread, cane toads will invade the Kimberley region of northwestern Australia within a few years. We urgently need to be able to predict which native species will be at risk from toads, and which will be relatively unaffected either because they are not killed by toads, or because they can rapidly learn, or evolve, in ways that reduce this impact and thus allow population recovery. We will obtain these data by exposing native animals to toads and recording the results; and thus, can identify the most important priorities for conservation efforts.Read moreRead less
Establishment of the Australian Cane Toad Genome Program. The Cane Toad is one of Australia's greatest environmental menaces, and is in the top 100 of the "World's Worst invader species". Over a billion toads infest Northern Australia, and they will soon invade WA and move further into NSW. Their poisons and voracious appetite could make many native mammals, birds and reptiles extinct. The only possibility to eradicate the Toad is by biological control, but there is no known control agent. We wi ....Establishment of the Australian Cane Toad Genome Program. The Cane Toad is one of Australia's greatest environmental menaces, and is in the top 100 of the "World's Worst invader species". Over a billion toads infest Northern Australia, and they will soon invade WA and move further into NSW. Their poisons and voracious appetite could make many native mammals, birds and reptiles extinct. The only possibility to eradicate the Toad is by biological control, but there is no known control agent. We will identify the 'Toad's Achilles' heel' against which control agents can be developed. We can do this by identifying every Toad gene. This project forms the first step to this goal by establishing the Australian Cane Toad Genome Program. Toad control will help preserve Australia's unique natural heritage.Read moreRead less