Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0883096
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Analytical and Preparative Enantioselective Chromatography. Enantiomers are forms of the same molecule that are non-superimposable mirror images of one another, like a left hand and a right hand. Because they are so similar they are very difficult to separate. However, they have very different biological properties, such as when used as drugs. One enantiomer may be beneficial while the other has no effect or sometimes is even toxic. Therefore it is important to be able to tell how much of ea ....Analytical and Preparative Enantioselective Chromatography. Enantiomers are forms of the same molecule that are non-superimposable mirror images of one another, like a left hand and a right hand. Because they are so similar they are very difficult to separate. However, they have very different biological properties, such as when used as drugs. One enantiomer may be beneficial while the other has no effect or sometimes is even toxic. Therefore it is important to be able to tell how much of each enantiomer is present in a sample and to be able to separate them. This facility will allow us to do both of these things.Read moreRead less
Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chem ....Nanoparticle driven templating of microspheres as chromatographic materials. This project aims to pioneer a novel, high-performing class of nano-patterned core-shell particles as chromatographic materials. It will use advanced polymerization and particle preparation techniques in combination with degradable nanoparticles design, to enable the plug-and-play assembly of chromatographic columns. Size-exclusion chromatography (SEC) is one of the most important analytical techniques for polymer chemistry. The expected outcomes of this project are faster measurement times and the possibility of imaging molecular weight distributions at a new level of detail. This project could place Australia at the cutting edge of size-exclusion chromatography phase design in partnership with a leading manufacturer of stationary phases.Read moreRead less