Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775676
Funder
Australian Research Council
Funding Amount
$290,000.00
Summary
An X-ray Diffraction Facility for Molecular Structure Determination. Characterisation of new chemical compounds demands proof of molecular structure. Whether for the identification of a new drug candidate, a material with novel properties or in the exploration of previously unknown types of compounds, X-ray crystallography is the definitive technique for this purpose. This proposal is for an X-ray diffractometer that will significantly enhance the capabilities of all synthetic and natural produc ....An X-ray Diffraction Facility for Molecular Structure Determination. Characterisation of new chemical compounds demands proof of molecular structure. Whether for the identification of a new drug candidate, a material with novel properties or in the exploration of previously unknown types of compounds, X-ray crystallography is the definitive technique for this purpose. This proposal is for an X-ray diffractometer that will significantly enhance the capabilities of all synthetic and natural products chemistry research programs undertaken at the Universities of Queensland and Newcastle, all currently in receipt of ARC funding. This research is aligned with the ARC National Research Priorities, of Promoting and Maintaining Good Health and Frontier Technologies for Building and Transforming Australian Industries.Read moreRead less
New vistas in porphyrin chemistry via metal-catalyzed couplings with hydrazine derivatives. This project will address basic scientific questions and develop new substances for use in molecular electronics and cancer therapy. We will make and study entirely new molecules derived from porphyrins, which in Nature have vital roles in photosynthesis, oxygen transport and enzyme catalysis. This breakthrough research will reveal knowledge vital to the advancement of fundamental chemical science and als ....New vistas in porphyrin chemistry via metal-catalyzed couplings with hydrazine derivatives. This project will address basic scientific questions and develop new substances for use in molecular electronics and cancer therapy. We will make and study entirely new molecules derived from porphyrins, which in Nature have vital roles in photosynthesis, oxygen transport and enzyme catalysis. This breakthrough research will reveal knowledge vital to the advancement of fundamental chemical science and also offer excellent training in cutting edge research for young Australian scientists. In addition, porphyrin-like substances are used in cancer diagnosis and treatment and have properties essential for the next generation of nanoelectronic devices, and this project is aimed at these eventual outcomes.Read moreRead less
Double Exposure Photoresists for the 32 and 22 nm Lithographic Nodes. The semiconductor industry is one of the largest world-wide, with annual revenue of $220B and employing over 1.5M people around the world. This project provides a unique opportunity for development within Australia of significant expertise in the field of double exposure lithography. The novel photoactive polymeric films to be developed are expected to support the next generation of microchips. A major outcome of this project ....Double Exposure Photoresists for the 32 and 22 nm Lithographic Nodes. The semiconductor industry is one of the largest world-wide, with annual revenue of $220B and employing over 1.5M people around the world. This project provides a unique opportunity for development within Australia of significant expertise in the field of double exposure lithography. The novel photoactive polymeric films to be developed are expected to support the next generation of microchips. A major outcome of this project will be establishment of Australia as a world-leader in this rapidly expanding field. Furthermore the technology can be applied broadly to many printing technologies.Read moreRead less
Advanced Lithographic Solutions using Block Copolymers: Integrating Self Assembly and Lithography. The semiconductor industry is one of the largest world-wide, with annual revenue of $220B and employing over 1.5M people around the world. This project provides a unique opportunity for development within Australia of significant expertise in the field of self assembly in photolithography. Plastics with tailored properties will be made and used to develop novel processes to reduce the defectivity i ....Advanced Lithographic Solutions using Block Copolymers: Integrating Self Assembly and Lithography. The semiconductor industry is one of the largest world-wide, with annual revenue of $220B and employing over 1.5M people around the world. This project provides a unique opportunity for development within Australia of significant expertise in the field of self assembly in photolithography. Plastics with tailored properties will be made and used to develop novel processes to reduce the defectivity in integrated circuit manufacture. The ultimate benefit will be faster and more energy efficient microprocessors. A major outcome of this project will be establishment of Australia as a world-leader in this rapidly expanding field. Furthermore, the technology can be applied broadly to many other applications such as high density data storage.Read moreRead less
Molecular grafting methods for design of peptide therapeutics. This project has the potential to lead to major economic benefits to Australia via royalty returns from novel drugs. Extra economic benefits derive from a reduction in the cost of treatment of diseases. The development of a new Australian developed peptide drug thus has the potential to lead to multimillion dollar savings to the Australian economy. Finally the project will provide training in state-of-the-art drug design that will e ....Molecular grafting methods for design of peptide therapeutics. This project has the potential to lead to major economic benefits to Australia via royalty returns from novel drugs. Extra economic benefits derive from a reduction in the cost of treatment of diseases. The development of a new Australian developed peptide drug thus has the potential to lead to multimillion dollar savings to the Australian economy. Finally the project will provide training in state-of-the-art drug design that will enhance Australia's pharmaceutical industry generally.Read moreRead less