Conquering Schistosomiasis In China: The Last Mile
Funder
National Health and Medical Research Council
Funding Amount
$2,432,780.00
Summary
Schistosomiasis (Bilharzia), caused by Schistosoma bloodflukes, is an ancient disease in the People’s Republic of China (PRC). After decades of control, the Chinese authorities have slated their intention to eliminate the disease by 2020. However, current diagnostic methods underestimate the true infection rates so we contend this target is unattainable. Supplementation of current control measures with additional public health interventions will be required to achieve the goal of elimination.
Novel Serological Tools To Aid Malaria Elimination In The Asia-Pacific
Funder
National Health and Medical Research Council
Funding Amount
$1,362,749.00
Summary
In 2014 Asia-Pacific leaders pledged a malaria free Asia-Pacific by 2030. We will contribute to this goal by developing novel antibody detection tests that can identify people with current and recent past infections. We will then evaluate the utility of these tests both in mass screening and treatment programs and for the rapid delineation of areas where transmission persists from those where it has been eliminated. This will address two major roadblocks to malaria elimination in our region.
Molecular dissection of malaria parasite motility and host-cell invasion across the lifecycle. Malaria parasites move in a unique way, gliding across cell surfaces and infecting host cells using a unique molecular motor. This research aims to understand the molecular mechanics behind parasite movement and use this to develop novel drugs that might throw a spanner in the parasite motor, blocking movement and thereby preventing malaria disease.
Discovery Early Career Researcher Award - Grant ID: DE120101529
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Transmission dynamics modelling of zoonotic neglected tropical diseases. This project will develop mathematical models to simulate zoonotic disease transmission and control. Results will provide novel insight for policy makers into effective interventions for schistosomiasis, echinococcosis and clonorchiasis, as well as provide a methodological platform for adaptation to other zoonotic emerging and re-emerging diseases.
A novel approach for controlling insect vectors of human disease. Insects are responsible for transmitting a wide variety of debilitating human diseases such as malaria, dengue and yellow fever. Unfortunately, there are very few options available for controlling these insect pests. This project will develop a novel, eco-friendly approach for control of mosquitoes and other important disease vectors.