Realistic assessment of biomarker transformation in the wastewater system. Wastewater-based epidemiology is an internationally recognised cost-effective tool to monitor population exposure to chemicals and infectious diseases including Covid-19. However, in-sewer degradation of critical biomarkers can limit their wastewater-based epidemiology suitability. This project aims to systematically evaluate the stability of a new suite of potential biomarkers and conduct the first Australia-wide assessm ....Realistic assessment of biomarker transformation in the wastewater system. Wastewater-based epidemiology is an internationally recognised cost-effective tool to monitor population exposure to chemicals and infectious diseases including Covid-19. However, in-sewer degradation of critical biomarkers can limit their wastewater-based epidemiology suitability. This project aims to systematically evaluate the stability of a new suite of potential biomarkers and conduct the first Australia-wide assessment on the impact of biomarker stability on wastewater-based epidemiology estimates using wastewater samples from ~65% of the Australian population. The project expects to generate knowledge to expand the application of wastewater-based epidemiology to reliably quantify exposure and status of well-being even in remote areasRead moreRead less
Development of strategy for comprehensive protection of Australia against respiratory diseases by real time detection of airborne pathogenic microbes. The project will develop a real time portable bioaerosol detector capable of identifying a presence of targeted microorganisms in the ambient air immediately upon their appearance. The device will become a powerful tool capable of protecting Australia by minimising the possible spread of infectious respiratory diseases causing global pandemics.
Revolutionising real-time genomic epidemiology in urban wastewater systems. This project aims to develop a real-time and high-resolution genomic tool to monitor and track pathogens in urban wastewater systems based on the portable third-generation sequencing platform. Pathogens sicken hundreds of millions of people, cost the global economy tens of billions of dollars annually, and are one of the leading causes of death worldwide. The current epidemiology approach, and data, are retrospective and ....Revolutionising real-time genomic epidemiology in urban wastewater systems. This project aims to develop a real-time and high-resolution genomic tool to monitor and track pathogens in urban wastewater systems based on the portable third-generation sequencing platform. Pathogens sicken hundreds of millions of people, cost the global economy tens of billions of dollars annually, and are one of the leading causes of death worldwide. The current epidemiology approach, and data, are retrospective and thus insufficient for timely intervention. Integrated with wastewater analysis for pharmaceuticals targeting pathogens, the sewer-based epidemiology approach of this project will greatly enhance public health by achieving early detection and informed control of infectious diseases.Read moreRead less