Origins and distributions of intraplate earthquakes. This project aims to investigate the behaviour and origin of intraplate earthquakes in Australia by developing a multi-million-year record of earthquakes using geological, geochronological, geospatial, seismological, statistical and numerical modelling data. It will use maximum credible magnitudes, maximum shaking intensities of intraplate earthquakes and spatiotemporal relationships between large prehistoric and contemporary earthquakes to im ....Origins and distributions of intraplate earthquakes. This project aims to investigate the behaviour and origin of intraplate earthquakes in Australia by developing a multi-million-year record of earthquakes using geological, geochronological, geospatial, seismological, statistical and numerical modelling data. It will use maximum credible magnitudes, maximum shaking intensities of intraplate earthquakes and spatiotemporal relationships between large prehistoric and contemporary earthquakes to improve models of future seismic hazard in Australia and globally. This will lead to improved predictions of future earthquake impacts in urban and natural environments and development of new paleoseismic techniques.Read moreRead less
Anomalous interfacial air-bubble dynamics: the importance of electrokinetic effects in thin film drainage. Air bubbles play important roles in numerous systems including plastics and paper recycling, water treatment and mineral separation processes, foodstuffs, beverages, cosmetics, cleaning products, fire retardants, and natural systems such as rivers, oceans and biological fluids. The properties and behaviour of these systems and processes depend on how air bubbles in water interact with each ....Anomalous interfacial air-bubble dynamics: the importance of electrokinetic effects in thin film drainage. Air bubbles play important roles in numerous systems including plastics and paper recycling, water treatment and mineral separation processes, foodstuffs, beverages, cosmetics, cleaning products, fire retardants, and natural systems such as rivers, oceans and biological fluids. The properties and behaviour of these systems and processes depend on how air bubbles in water interact with each other, and/or with other materials. Currently our understanding of the bubble interactions is incomplete. The improved understanding gained from this research project will lead to better ability to control the properties of systems and processes such as those listed above.Read moreRead less
The application of clumped isotope thermometry to the terrestrial environment. Clumped-isotope geochemistry, a novel method for measuring the temperature of formation of carbonate minerals, will be applied to terrestrial materials (soil carbonates, lake deposits and speleothems) from Australia and New Zealand. The method relates the abundance or 'clumping' of rare isotopes (for example, carbon dioxide of mass 47 as carbon-13, oxygen-18, oxygen-16) extracted from carbonates to their formation tem ....The application of clumped isotope thermometry to the terrestrial environment. Clumped-isotope geochemistry, a novel method for measuring the temperature of formation of carbonate minerals, will be applied to terrestrial materials (soil carbonates, lake deposits and speleothems) from Australia and New Zealand. The method relates the abundance or 'clumping' of rare isotopes (for example, carbon dioxide of mass 47 as carbon-13, oxygen-18, oxygen-16) extracted from carbonates to their formation temperature and is independent of the oxygen-18:oxygen-16 value of the host water from which the mineral precipitated. The materials to be investigated span the Last Glacial-Interglacial Transition and will provide robust past temperature estimates and the delta-oxygen-18 values of waters, thereby permitting hydrological balances (for example, precipitation/evaporation) to be constructed. Read moreRead less
Climate and environmental history of SE Queensland dunefields. This project aims to generate fundamental information about the timing and mode of formation of sand dunes in the world's largest downdrift sand system, Cooloola and Fraser Island, Queensland. The project aims to provide a world class record of climate variability, sea-level change and long term climate change from the sub-tropics of Australia, an area critical to understanding global climate links and sea-level change but where high ....Climate and environmental history of SE Queensland dunefields. This project aims to generate fundamental information about the timing and mode of formation of sand dunes in the world's largest downdrift sand system, Cooloola and Fraser Island, Queensland. The project aims to provide a world class record of climate variability, sea-level change and long term climate change from the sub-tropics of Australia, an area critical to understanding global climate links and sea-level change but where high quality long-term records are sparse and little investigated. This project will also underpin the outstanding universal value of the Fraser Island World Heritage Area which is based on the area being the world's largest sand island, but for which scientific understanding of the sand dunes is remarkably poor.Read moreRead less
Evolutionary origins of sexual parasitism in an Australian freshwater fish. Carp gudgeons are the most abundant, widespread and biodiverse freshwater fishes in southeastern Australia. The unacknowledged presence of many cryptic species and sexually-parasitic lineages severely taints all research on this cornerstone group. This project aims to provide unrivalled evolutionary, genomic, and taxonomic insights into this new instance of vertebrate sexual parasitism, which offers a unique mix of resea ....Evolutionary origins of sexual parasitism in an Australian freshwater fish. Carp gudgeons are the most abundant, widespread and biodiverse freshwater fishes in southeastern Australia. The unacknowledged presence of many cryptic species and sexually-parasitic lineages severely taints all research on this cornerstone group. This project aims to provide unrivalled evolutionary, genomic, and taxonomic insights into this new instance of vertebrate sexual parasitism, which offers a unique mix of research advantages not displayed by any other sexual/unisexual complex. The knowledge gained could impact many research fields, including evolutionary theory addressing the unexplainable prevalence of sex, native fish ecology, and environmental monitoring of the Murray-Darling Basin, an ecosystem of world significance.Read moreRead less
LIPID AND LIPOPROTEIN ADSORPTION AT BIOMATERIALS AND BIO-DIAGNOSTICS INTERFACES. This project aims to investigate molecular mechanisms involved in the formation of undesired biological deposits on synthetic materials and thereby help establish the scientific basis for the rational design of materials with improved compatibility with biological fluids and the engineering of a new generation of biomedical implant devices and bio-diagnostic devices. It is well known that proteins accumulate on synt ....LIPID AND LIPOPROTEIN ADSORPTION AT BIOMATERIALS AND BIO-DIAGNOSTICS INTERFACES. This project aims to investigate molecular mechanisms involved in the formation of undesired biological deposits on synthetic materials and thereby help establish the scientific basis for the rational design of materials with improved compatibility with biological fluids and the engineering of a new generation of biomedical implant devices and bio-diagnostic devices. It is well known that proteins accumulate on synthetic solid surfaces. This project proposes to investigate whether lipids and lipoproteins also play key roles in the initiation of biological adsorption processes. Combined with the study of the interfacial forces responsible, this information will guide the design of preventative strategies.Read moreRead less
A new strategy for design flood estimation in a nonstationary climate. Evidence suggests that global warming will result in an increase in the frequency and/or magnitude of heavy rainfall, leading to flooding with potentially devastating consequences. This study provides a renewed focus on design flood estimation that takes into account a changing climate where assumptions of stationarity are no longer tenable.
Physico-chemical and Biopharmaceutical Investigations of Novel Drug Delivery Systems for Oral Administration of Lipophilic Drugs. The new platform technology for carrying lipophilic molecules will be applicable to many molecules currently under development by Australian Industry and will inspire novel encapsulation approaches to new and existing drugs as well as functional foods and nutraceuticals. Improved oral bioavailability of anticancer drugs will improve the quality of life of patients, re ....Physico-chemical and Biopharmaceutical Investigations of Novel Drug Delivery Systems for Oral Administration of Lipophilic Drugs. The new platform technology for carrying lipophilic molecules will be applicable to many molecules currently under development by Australian Industry and will inspire novel encapsulation approaches to new and existing drugs as well as functional foods and nutraceuticals. Improved oral bioavailability of anticancer drugs will improve the quality of life of patients, reduce health care costs and provide broader benefits to the community. The Australian biotechnology/pharmaceutical industries can share in a greater proportion of the US$50 billion market for specialised drug delivery, which is increasing by 20% annually. Australia's scientific competitiveness will be strengthened in the fields of nano-encapsulation and colloidal delivery.Read moreRead less
Measuring and modelling the mechanical response of soils incorporating recycled tyres. Civil engineers use backfill to refill excavated areas around new structures. They have found recently that rubber chips and shredded rubber make excellent backfill when combined with a small percentage of cement to make ‘rubber soil’. The widespread use of rubber soil therefore offers a tremendous opportunity to make use of a serious waste product to achieve important engineering outcomes. However, too little ....Measuring and modelling the mechanical response of soils incorporating recycled tyres. Civil engineers use backfill to refill excavated areas around new structures. They have found recently that rubber chips and shredded rubber make excellent backfill when combined with a small percentage of cement to make ‘rubber soil’. The widespread use of rubber soil therefore offers a tremendous opportunity to make use of a serious waste product to achieve important engineering outcomes. However, too little is known about the technology. This project will model the behaviour of rubber soil in order to introduce it as an environmentally sustainable, cost-effective and technically sound choice of geomaterial for both standard and non-standard geotechnical structures.Read moreRead less
Climate model validation and generation of probabilistic climate projections using data from Phase 5 of the Climate Model Intercomparison Project. New climate model results will be compared with observations to test model skill. Probabilistic projections of regional-scale climate change will be developed and used to investigate a number of ecosystem impact case studies.