Engineered nanostructured materials via continuous polymer assembly for advanced bioapplications. The development of new and flexible processes is critical to the design and construction of advanced materials for future applications in nano- and biotechnology. This project will develop innovative and versatile "bottom-up" nanotechnology techniques to afford nanostructured materials with unprecedented properties. This project has the potential to revolutionise current approaches for forming surfa ....Engineered nanostructured materials via continuous polymer assembly for advanced bioapplications. The development of new and flexible processes is critical to the design and construction of advanced materials for future applications in nano- and biotechnology. This project will develop innovative and versatile "bottom-up" nanotechnology techniques to afford nanostructured materials with unprecedented properties. This project has the potential to revolutionise current approaches for forming surface coatings, films and advanced particles, leading to significant outcomes in diverse areas, including drug delivery, biomaterial implants and biocatalysis. The project will contribute to the development of a robust Australian nanotechnology industry, with the advanced materials developed expected to have health benefits for Australian citizens.Read moreRead less
Building Molecularly Engineered Polymer Nanomaterials. The development of new technologies at the interface between nano- and biotechnology promises to revolutionise healthcare and medicine. This research program will involve the design and synthesis of responsive and programmable polymers and their assembly to form next-generation, engineered materials. The nanomaterials prepared are expected to lead to the development of techniques that enable new types of minimally invasive diagnostics and th ....Building Molecularly Engineered Polymer Nanomaterials. The development of new technologies at the interface between nano- and biotechnology promises to revolutionise healthcare and medicine. This research program will involve the design and synthesis of responsive and programmable polymers and their assembly to form next-generation, engineered materials. The nanomaterials prepared are expected to lead to the development of techniques that enable new types of minimally invasive diagnostics and therapeutics as well as smaller devices. The interdisciplinary research program will cement Australia's position as a leading country in nanobiotechnology research and development.Read moreRead less
Engineering and Assembly of Bioinspired Nanostructured Materials. Scientific and technological advances at the frontiers of nano- and bio-technology are poised to revolutionise healthcare and medicine. This project will involve the design, synthesis and engineering of functional biopolymer building blocks. These 'smart' biopolymers will then be assembled into responsive, nanostructured materials for targeted drug delivery and biosensing applications. These materials are expected to ultimately ha ....Engineering and Assembly of Bioinspired Nanostructured Materials. Scientific and technological advances at the frontiers of nano- and bio-technology are poised to revolutionise healthcare and medicine. This project will involve the design, synthesis and engineering of functional biopolymer building blocks. These 'smart' biopolymers will then be assembled into responsive, nanostructured materials for targeted drug delivery and biosensing applications. These materials are expected to ultimately have health benefits for Australian citizens and contribute to the development of a robust Australian nanobiotechnology industry. The project will also provide excellent opportunities for the development of outstanding young scientists and will foster exciting, multidisciplinary collaborations.Read moreRead less
Nanoscale Coating and Biomodification of Colloids for Biological Applications. The research entails the preparation of novel biofunctional colloids of nanometer to micrometer dimensions and their utilisation in biological applications. Self-assembly processes will be exploited to achieve nanoscale biomodification of technologically important colloid particles, including latex beads and rare earth and semiconductor nanoparticles. The studies conducted will generate fundamental knowledge pertainin ....Nanoscale Coating and Biomodification of Colloids for Biological Applications. The research entails the preparation of novel biofunctional colloids of nanometer to micrometer dimensions and their utilisation in biological applications. Self-assembly processes will be exploited to achieve nanoscale biomodification of technologically important colloid particles, including latex beads and rare earth and semiconductor nanoparticles. The studies conducted will generate fundamental knowledge pertaining to the underlying factors that govern the formation of biofunctional colloid particles through self-assembly. This is essential for the development of tailored colloids that will meet the demands placed on nanomaterials synthesis and performance by nanotechnology. The colloids prepared will find new applications in medicine, biocatalysis and bioassays.Read moreRead less
Special Research Initiatives - Grant ID: SR0354658
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Nanoparticle Network. Nanoscale materials are objects with one dimension less than about 20nm in size. Such exotic materials display unique, size-dependent properties (called "quantum size effects"). These materials will form the basis for many of the technological advances of the 21st Century. "The Nanoparticle Network" is a consortium dedicated to the exploration of different nanoscale materials and the origin of quantum size effects. The Network aims to enhance the uptake of all types of ....The Nanoparticle Network. Nanoscale materials are objects with one dimension less than about 20nm in size. Such exotic materials display unique, size-dependent properties (called "quantum size effects"). These materials will form the basis for many of the technological advances of the 21st Century. "The Nanoparticle Network" is a consortium dedicated to the exploration of different nanoscale materials and the origin of quantum size effects. The Network aims to enhance the uptake of all types of nanoparticle based technologies through an integrated network of scientists and engineers in conjunction with industry partners and government research institutions.
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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0237527
Funder
Australian Research Council
Funding Amount
$170,000.00
Summary
Bioscope IV : Advanced Scanned Probe Microscopy. The Atomic Force Microscope presents a unique view of the microscopic and molecular world, for it is sensitive to force alone. This instrument can accurately map force over a surface at the molecular scale; picoNewtons at nanometre resolution. The host of intermolecular forces which cause phenomena such as self-assembly, colloid stability, cell interactions and friction are only directly measurable with this technique. In this field of force meas ....Bioscope IV : Advanced Scanned Probe Microscopy. The Atomic Force Microscope presents a unique view of the microscopic and molecular world, for it is sensitive to force alone. This instrument can accurately map force over a surface at the molecular scale; picoNewtons at nanometre resolution. The host of intermolecular forces which cause phenomena such as self-assembly, colloid stability, cell interactions and friction are only directly measurable with this technique. In this field of force measurement Australian researchers are leaders. The proposed instrument expands the capabilities of this effort, and develops exciting new directions including the direct manipulation of molecules through a novel feedback and control (haptic) interface.Read moreRead less
Biologically-Inspired Recognition and Processing in Colloidal Systems. The proposed research will enhance the understanding of forces and adsorption in biologically-inspired synthetic systems, and thereby create new strategies for improving selective adsorption, stabilization, coagulation, and separation. The expected outcomes are: increased understanding of chiral interactions at surfaces, a technique for rapid measurement of surface selectivity, new and better agents for chiral separation, a ....Biologically-Inspired Recognition and Processing in Colloidal Systems. The proposed research will enhance the understanding of forces and adsorption in biologically-inspired synthetic systems, and thereby create new strategies for improving selective adsorption, stabilization, coagulation, and separation. The expected outcomes are: increased understanding of chiral interactions at surfaces, a technique for rapid measurement of surface selectivity, new and better agents for chiral separation, a reduction in the use of organic pollutants, new methods for colloidal processing that will enable the preparation of new materials, and new surface coatings for increasing the useful life-time of medical implants.Read moreRead less
Nanoengineered Colloids and thin films through self-assembly with potential applications in Bioscince and Nanotechnology. The proposed research program will focus on the preparation, characterisation and application of novel, small (nanometer size) particles and thin (micrometer thick)films derived from such particles. These new and advanced materials will be prepared by usinf a recently developed, highly versatile and facile technology to coat particles in solution. The strategy to be used en ....Nanoengineered Colloids and thin films through self-assembly with potential applications in Bioscince and Nanotechnology. The proposed research program will focus on the preparation, characterisation and application of novel, small (nanometer size) particles and thin (micrometer thick)films derived from such particles. These new and advanced materials will be prepared by usinf a recently developed, highly versatile and facile technology to coat particles in solution. The strategy to be used entails the step-by-step construction of well-defined layers of different composition on particles and flat surfaces, thereby allowing unprecendented control over the material properties and function. This will provide new avenues for the application of nanoscale materials in biotechnology and nanotechnology.Read moreRead less
Mechanisms of enhancement of absorption of poorly water-soluble drugs from the gastrointestinal tract mediated by lipids, surfactants and polymers. This project will provide technological advances with significant benefits in terms of improved drug treatment, and therefore health outcomes for Australia. The projects builds on internationally recognised research strengths at Monash University in lipid-based drug delivery, and connects Monash and Australia with applied research in the multination ....Mechanisms of enhancement of absorption of poorly water-soluble drugs from the gastrointestinal tract mediated by lipids, surfactants and polymers. This project will provide technological advances with significant benefits in terms of improved drug treatment, and therefore health outcomes for Australia. The projects builds on internationally recognised research strengths at Monash University in lipid-based drug delivery, and connects Monash and Australia with applied research in the multinational pharmaceutical industry. This will enhance the standing of Australian biomedical research in the pharmaceutical world and directly facilitate a partnership between Monash and Capsugel in commercialisation of the outcomes of the project. The project will also train Australian scientists in skills that are in great demand in the developing pharmaceutical industry in Australia.Read moreRead less