Improving explosive emulsions by understanding surfactant interactions. This project will design new surfactants that will lead to more cost effective, stable and reliable explosive emulsions. The pressure required to force dispersed phase droplets to coalesce will be measured both directly and by osmotic stress. These parameters have not previously been measured for an inverse emulsion system. The measurements made will be correlated to the structure of the stabilising surfactant enabling new a ....Improving explosive emulsions by understanding surfactant interactions. This project will design new surfactants that will lead to more cost effective, stable and reliable explosive emulsions. The pressure required to force dispersed phase droplets to coalesce will be measured both directly and by osmotic stress. These parameters have not previously been measured for an inverse emulsion system. The measurements made will be correlated to the structure of the stabilising surfactant enabling new and more effective surfactants to be designed.Read moreRead less
Sustainable surfactants from Australian oilseeds. This project aims to develop a new generation of sustainable surfactants utilising Australian-grown oilseed feedstocks. These molecules are designed to replace current materials made from petroleum and palm oil, to fulfil a key role as the next generation of bio-resourced detergents and emulsifiers. The work seek to develop a library of new molecules to better understand the relationship between molecular structure and performance, through cuttin ....Sustainable surfactants from Australian oilseeds. This project aims to develop a new generation of sustainable surfactants utilising Australian-grown oilseed feedstocks. These molecules are designed to replace current materials made from petroleum and palm oil, to fulfil a key role as the next generation of bio-resourced detergents and emulsifiers. The work seek to develop a library of new molecules to better understand the relationship between molecular structure and performance, through cutting edge lab testing and utilising national infrastructure, guiding the use of new components in formulating new products. It is anticipated that the surfactants generated will find uses in household cleaning and personal care products, providing high value chemicals from key Australian crops.Read moreRead less
Fluorous Chemistry: New tagging agents and heterocyclic-based fluorous surfactants. Fluorous chemistry is emerging as a powerful adjunct to areas of conventional parallel and combinatorial organic syntheses, and its introduction has revolutionised separation technologies. In this project two new fluorous tagging strategies will be investigated in an effort to broaden the scope of reagents that can used in synthesis. Efforts will be directed to chiral auxiliaries and to fluorous catalyst ligands. ....Fluorous Chemistry: New tagging agents and heterocyclic-based fluorous surfactants. Fluorous chemistry is emerging as a powerful adjunct to areas of conventional parallel and combinatorial organic syntheses, and its introduction has revolutionised separation technologies. In this project two new fluorous tagging strategies will be investigated in an effort to broaden the scope of reagents that can used in synthesis. Efforts will be directed to chiral auxiliaries and to fluorous catalyst ligands. In addition, a novel class of fluorous surfactant will be investigated, for its surface properties (including its ability to self assemble) and for its utility in two specific applications, selective membrane-bound protein extraction (relevant to proteomics) and ophthalmics (biomaterials).Read moreRead less
Special Research Initiatives - Grant ID: SR180200051
Funder
Australian Research Council
Funding Amount
$497,638.00
Summary
Integrated platform technologies for remediation of PFAS contaminated water. This project aims to develop low cost platform technologies using our patented high capacity adsorbent material for the removal of perfluoralkyl substances (PFAS) from contaminated water sources in Australia. Our advanced adsorbent material is made from a novel sulfur co-polymer and activated carbon, both of which have high affinity for PFAS, but when combined as a composite provide significant advantages for PFAS remed ....Integrated platform technologies for remediation of PFAS contaminated water. This project aims to develop low cost platform technologies using our patented high capacity adsorbent material for the removal of perfluoralkyl substances (PFAS) from contaminated water sources in Australia. Our advanced adsorbent material is made from a novel sulfur co-polymer and activated carbon, both of which have high affinity for PFAS, but when combined as a composite provide significant advantages for PFAS remediation. This adsorbent will be applied in mobile water treatment plants for remediation of PFAS contaminated aquifers. We will also develop point-of-use water filters for individual, domestic use from the adsorbent, thus empowering individuals and local communities by delivering tangible solutions to Australia’s PFAS crisis.Read moreRead less
Nanomaterials: Probing supramolecular self-assembly at the solution/solid interface. Australia's competitiveness in nanotechnology must be underpinned by fundamental innovation and research. In a "bottom-up" approach to nanomaterials, it is important to understand, for the smallest possible machines that can be produced, how singular molecular components interact with one another, both during the assembly of any device and afterwards as it performs its function. For working devices the molecule ....Nanomaterials: Probing supramolecular self-assembly at the solution/solid interface. Australia's competitiveness in nanotechnology must be underpinned by fundamental innovation and research. In a "bottom-up" approach to nanomaterials, it is important to understand, for the smallest possible machines that can be produced, how singular molecular components interact with one another, both during the assembly of any device and afterwards as it performs its function. For working devices the molecules need to be assembled on a solid surface so that they can work in unison. In this project, in conjunction with researchers at the University of Cambridge, we use the new technique of gel-phase NMR spectroscopy to understand the factors involved as molecular components assemble on the surface of polystyrene beads.Read moreRead less
Supramolecular assembly in photovoltaic electrode design: Studies of ordered porphyrin/acceptor complexes on polythiophene electrodes. This research outlines an improved way to develop dye-sensitised photovoltaic solar cells for the conversion of sunlight into electricity, by increasing the molecular order of the cell components using host, guest interrelationships. As such, it addresses a problem of international concern 'How to reduce greenhouse gas emissions and stop global warming?' since s ....Supramolecular assembly in photovoltaic electrode design: Studies of ordered porphyrin/acceptor complexes on polythiophene electrodes. This research outlines an improved way to develop dye-sensitised photovoltaic solar cells for the conversion of sunlight into electricity, by increasing the molecular order of the cell components using host, guest interrelationships. As such, it addresses a problem of international concern 'How to reduce greenhouse gas emissions and stop global warming?' since solar cells do not produce carbon dioxide. To achieve our goals we draw on the skills of a team of experts from Australia (synthetic organic chemists), New Zealand (polymer and surface chemists) and Italy (photochemist and photophysicist). Such research is very appropriate for regional Australia, especially Central Queensland.Read moreRead less
Metal catalysed reactions in organic synthesis. The major aim of this project is to develop highly efficient metal-catalysed routes to pharmaceuticals, e.g. new antibiotics and other commercially important organic molecules.
Particular attention will be paid to developing systems which facilitate the addition of readily available, cheap small molecules, e.g. hydrogen and carbon monoxide, to unsaturated organic molecules with high regio- and stereoselectivity.
Worldwide demand for enantiomeric ....Metal catalysed reactions in organic synthesis. The major aim of this project is to develop highly efficient metal-catalysed routes to pharmaceuticals, e.g. new antibiotics and other commercially important organic molecules.
Particular attention will be paid to developing systems which facilitate the addition of readily available, cheap small molecules, e.g. hydrogen and carbon monoxide, to unsaturated organic molecules with high regio- and stereoselectivity.
Worldwide demand for enantiomerically pure chiral molecules (i.e. one mirror-image form) continues to rise. New metal-catalysed asymmetric syntheses will help meet this challenge. Tandem metal-catalysed reactions will be used to prepare new heterocyclic compounds with potential as specific metal binding agents and biosensors.Read moreRead less
Biomimetic and Methodology Based Total Synthesis of Bioactive Natural Products. The proposal will study the synthesis of novel natural products that possess biological activities. Most significantly, this project will deliver compounds with anticancer activity. In addition, chemistry may be developed which could be utilised to synthesise a number of bioactive molecules. The rewards of the synthesis of compounds and application for the treatment of cancer and other diseases are enormous for the ....Biomimetic and Methodology Based Total Synthesis of Bioactive Natural Products. The proposal will study the synthesis of novel natural products that possess biological activities. Most significantly, this project will deliver compounds with anticancer activity. In addition, chemistry may be developed which could be utilised to synthesise a number of bioactive molecules. The rewards of the synthesis of compounds and application for the treatment of cancer and other diseases are enormous for the community and in the education and training of scientists.Read moreRead less
Total Synthesis of Novel Metabolites form Microorganisms. The main aim of this proposal is to achieve the chemical synthesis of a number of biologically active novel natural products isolated from microorganisms. This will involve the development of new methods as well as improvement on exisiting approaches developed so far. The targets will include the myxobacteria metabolites crocacins A, B and D and apicularen A, the streptomyces metabolites reveromycin A and spirofungin A and the fungal meta ....Total Synthesis of Novel Metabolites form Microorganisms. The main aim of this proposal is to achieve the chemical synthesis of a number of biologically active novel natural products isolated from microorganisms. This will involve the development of new methods as well as improvement on exisiting approaches developed so far. The targets will include the myxobacteria metabolites crocacins A, B and D and apicularen A, the streptomyces metabolites reveromycin A and spirofungin A and the fungal metabolite zaragozic acid C.
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New synthetic strategies towards higher order fullerenes. Fullerene or C60 is a novel soccer-ball shaped molecule with many potential applications as new materials and pharmaceutical drugs. This project aims to develop novel methods for the preparation of new fullerene derivatives that will have potential future applications in materials science, medicinal/pharmaceutical chemistry and chemical synthesis.