Expression profiling of giant cells induced in host plant roots by root-knot nematodes. Root-knot nematodes cause crop losses of over $400 million per annum in Australia. Control by toxic chemical nematicodes is expensive and can pollute groundwater. Benefits from this research for the Australian community are: (i) it will ensure that Australian researchers stay at the forefront of research in plant nematology, (ii) it provides significant local and international linkages that will stimulate res ....Expression profiling of giant cells induced in host plant roots by root-knot nematodes. Root-knot nematodes cause crop losses of over $400 million per annum in Australia. Control by toxic chemical nematicodes is expensive and can pollute groundwater. Benefits from this research for the Australian community are: (i) it will ensure that Australian researchers stay at the forefront of research in plant nematology, (ii) it provides significant local and international linkages that will stimulate research outputs, and (iii) new knowledge will be generated on how plants respond to attack by nematodes - this will generate new intellectual property, leading to better control methods and reduced costs that will support rural communities, and reduce environmental pollution.Read moreRead less
Factors responsible for host resistance to the pathogen Sclerotinia sclerotiorum for developing effective disease management in vegetable brassicas. Through successful identification of host resistance in vegetable Brassicas to Sclerotinia sclerotiorum and determining the factors associated with this resistance, breeders, for the first time, will be able to develop varieties with resistance against this difficult-to-manage pathogen. Benefits include prevention of severe losses in vegetable Bras ....Factors responsible for host resistance to the pathogen Sclerotinia sclerotiorum for developing effective disease management in vegetable brassicas. Through successful identification of host resistance in vegetable Brassicas to Sclerotinia sclerotiorum and determining the factors associated with this resistance, breeders, for the first time, will be able to develop varieties with resistance against this difficult-to-manage pathogen. Benefits include prevention of severe losses in vegetable Brassicas from Sclerotinia, and more viable and sustainable production with less reliance upon fungicides and toxic or ineffective fumigants. This research addresses the National Research Priority, an environmentally sustainable Australia, and the priority goal transforming existing industries, and will particularly benefit Australian horticultural communities.Read moreRead less
Biosynthesis and functions of two phytotoxins in Septoria nodorum blotch. This project aims to investigate how a fungal plant pathogen makes and uses small bioactive molecules to facilitate infection. It will characterise the function of the genes and enzymes involved in the biosynthesis of a light-activated phytotoxic molecule and a potential anti-plant defence molecule found in the pathogenic wheat fungus Parastagonospora nodorum, and investigate their contribution to disease development. Expe ....Biosynthesis and functions of two phytotoxins in Septoria nodorum blotch. This project aims to investigate how a fungal plant pathogen makes and uses small bioactive molecules to facilitate infection. It will characterise the function of the genes and enzymes involved in the biosynthesis of a light-activated phytotoxic molecule and a potential anti-plant defence molecule found in the pathogenic wheat fungus Parastagonospora nodorum, and investigate their contribution to disease development. Expected outcomes include better understanding of plant-microbe interactions, disease management strategies, technologies for identifying biosynthetic pathways in other fungi, and enzyme technology for synthesising molecules. This could lead to new herbicides, biopesticides and drugs.Read moreRead less
Fungal Ribosomally Synthesised and Post-translationally Modified Peptides. Fungi produce an array of molecules called secondary metabolites (SMs) that impact on everyday life (e.g. penicillin). This project aims to investigate a new class of fungal peptide SMs called RiPPs which are structurally unique from existing molecules and offer the exciting prospect of harbouring new and novel biological activities. This project expects to discover the mechanisms of RiPP synthesis and their biological ro ....Fungal Ribosomally Synthesised and Post-translationally Modified Peptides. Fungi produce an array of molecules called secondary metabolites (SMs) that impact on everyday life (e.g. penicillin). This project aims to investigate a new class of fungal peptide SMs called RiPPs which are structurally unique from existing molecules and offer the exciting prospect of harbouring new and novel biological activities. This project expects to discover the mechanisms of RiPP synthesis and their biological roles in plant pathogenic fungi, and uncover and engineer novel RiPPs with desired bioactivities. The expected outcome from this project will be a seminal advance in fungal SM biology which should provide significant benefits through the generation of exciting new lead molecules for the agricultural and medical industries.Read moreRead less
Assessing plant virus threats to indigenous Western Australian flora: implications for biodiversity, conservation, ecosystem reclamation and the wildflower industry. Australia's unique flora is a valuable asset, not only in terms of aesthetic value, ecotourism, commercial floriculture, the environment and rural communities, but also in relation to water quality, a sink for carbon, and a source for novel medicinal chemicals. The threat posed by plant viruses to native flora has largely been igno ....Assessing plant virus threats to indigenous Western Australian flora: implications for biodiversity, conservation, ecosystem reclamation and the wildflower industry. Australia's unique flora is a valuable asset, not only in terms of aesthetic value, ecotourism, commercial floriculture, the environment and rural communities, but also in relation to water quality, a sink for carbon, and a source for novel medicinal chemicals. The threat posed by plant viruses to native flora has largely been ignored, but with global climate change, virus infection will become increasingly important. This study will document the role of plant viruses in the sustainability of Australia's floral heritage and industries, and develop strategies to limit virus spread through plant nurseries, rehabilitation of degraded ecosystems and conservation of threatened species.Read moreRead less