Development of Novel Pesticidal Agents. We have discovered a family of naturally occurring plant proteins called the cyclotides that have potent insecticidal activity against Helicoverpa species, one of the major pests on cotton and corn in Australia and world wide. Preliminary evidence has shown that they also have activity against major pests to livestock in Australia, including sheep blowflies. To develop these proteins as potential pesticidal agents it is necessary to understand the struct ....Development of Novel Pesticidal Agents. We have discovered a family of naturally occurring plant proteins called the cyclotides that have potent insecticidal activity against Helicoverpa species, one of the major pests on cotton and corn in Australia and world wide. Preliminary evidence has shown that they also have activity against major pests to livestock in Australia, including sheep blowflies. To develop these proteins as potential pesticidal agents it is necessary to understand the structural basis for their activity. We will do this by chemically synthesising peptides with selected residues mutated to determine their effects on activity.Read moreRead less
Protecting tomato crops from Fusarium wilt through the efficient application of new genetic resources. The tomato industry is a major horticultural industry in Australia, and Queensland is the major producer of tomatoes for the fresh food market. In Queensland, the tomato industry has expanded in the face of the threat that Fusarium wilt could re-emerge as a major disease problem. This research will ensure that measures can be taken quickly and efficiently to protect existing genetic resources u ....Protecting tomato crops from Fusarium wilt through the efficient application of new genetic resources. The tomato industry is a major horticultural industry in Australia, and Queensland is the major producer of tomatoes for the fresh food market. In Queensland, the tomato industry has expanded in the face of the threat that Fusarium wilt could re-emerge as a major disease problem. This research will ensure that measures can be taken quickly and efficiently to protect existing genetic resources used to control Fusarium wilt. It will also improve our knowledge about the mechanisms plants use to defend themselves against Fusarium wilt diseases.Read moreRead less