Peptidic spider toxins: a novel paradigm for control of insect pests. Many insects are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by insects are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, ....Peptidic spider toxins: a novel paradigm for control of insect pests. Many insects are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by insects are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, many of these insect pests have developed resistance to chemical insecticides. The aim of this research program is to develop a new generation of environmentally-friendly natural products and insect-resistant crops that can be used to control insect pests on farms and around the home and garden.Read moreRead less
Orally active spider toxins: a novel paradigm for control of insect pests. Many insects and other arthropods are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by arthropods are also responsible for diseases such as dengue, Japanese encephalitis, and Ros ....Orally active spider toxins: a novel paradigm for control of insect pests. Many insects and other arthropods are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by arthropods are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, many of these arthropod pests have developed resistance to chemical insecticides. This aim of this research program is to develop a new generation of environmentally-friendly natural products that can be used to control arthropod pests on pets, farms, and around the home and garden.Read moreRead less
Safeguarding Australia against invasive arthropod pests. An increasingly serious public health issue for Australia is the emergence of infectious diseases disseminated by arthropods such as ticks and mosquitoes. Arthropod-borne viruses are already the major human pathogens in Australia, and they disproportionately affect Aboriginal communities. The aim of this research is to develop environmentally-sustainable methods for controlling arthropods that destroy crops or disseminate human and animal ....Safeguarding Australia against invasive arthropod pests. An increasingly serious public health issue for Australia is the emergence of infectious diseases disseminated by arthropods such as ticks and mosquitoes. Arthropod-borne viruses are already the major human pathogens in Australia, and they disproportionately affect Aboriginal communities. The aim of this research is to develop environmentally-sustainable methods for controlling arthropods that destroy crops or disseminate human and animal disease. These insecticides will not only provide benefits within Australian territories, but will be useful to our defence forces when operating in overseas locations where arthropod pests are a problem (e.g., malarial regions of Iraq).Read moreRead less
Expression profiling of giant cells induced in host plant roots by root-knot nematodes. Root-knot nematodes cause crop losses of over $400 million per annum in Australia. Control by toxic chemical nematicodes is expensive and can pollute groundwater. Benefits from this research for the Australian community are: (i) it will ensure that Australian researchers stay at the forefront of research in plant nematology, (ii) it provides significant local and international linkages that will stimulate res ....Expression profiling of giant cells induced in host plant roots by root-knot nematodes. Root-knot nematodes cause crop losses of over $400 million per annum in Australia. Control by toxic chemical nematicodes is expensive and can pollute groundwater. Benefits from this research for the Australian community are: (i) it will ensure that Australian researchers stay at the forefront of research in plant nematology, (ii) it provides significant local and international linkages that will stimulate research outputs, and (iii) new knowledge will be generated on how plants respond to attack by nematodes - this will generate new intellectual property, leading to better control methods and reduced costs that will support rural communities, and reduce environmental pollution.Read moreRead less
Generating broad and stable resistance to gemini- and nanoviruses. The ssDNA geminiviruses and nanoviruses are considered a major threat to crop production in the tropics and subtropics. There are currently no effective control strategies for these viruses. We have been developing a novel transgenic strategy for generating resistance to ssDNA viruses based on the activation of a suicide gene in the presence of the viral Rep protein. Importantly, we have demonstrated proof-of-principle using Toba ....Generating broad and stable resistance to gemini- and nanoviruses. The ssDNA geminiviruses and nanoviruses are considered a major threat to crop production in the tropics and subtropics. There are currently no effective control strategies for these viruses. We have been developing a novel transgenic strategy for generating resistance to ssDNA viruses based on the activation of a suicide gene in the presence of the viral Rep protein. Importantly, we have demonstrated proof-of-principle using Tobacco yellow dwarf mastrevirus. In this project, we aim to further develop this strategy into a broad and stable mechanism for generating resistance to all known geminiviruses and nanoviruses.Read moreRead less
To move or not to move: are insect movement strategies driven by plant-induced defences? Plants change chemically when damaged by insects. By showing how movement and feeding is related to these induced defences we can manipulate plant defences to resist insect attack in a more focused way. Our target insects are major pests against which we use large amounts of insecticide. Our research will decrease insect damage to crops using existing genetic machinery of plants as opposed to inserting 'nove ....To move or not to move: are insect movement strategies driven by plant-induced defences? Plants change chemically when damaged by insects. By showing how movement and feeding is related to these induced defences we can manipulate plant defences to resist insect attack in a more focused way. Our target insects are major pests against which we use large amounts of insecticide. Our research will decrease insect damage to crops using existing genetic machinery of plants as opposed to inserting 'novel' toxin-expressing genes. This project builds on Australia's strong record of achievement in agricultural and natural resource research by increasing understanding of the interplay between plant traits and insects. We will build cross-disciplinary research capacity training a new generation of biologists in an exciting area of science.Read moreRead less
Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined these systems and limited prospect for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel natural compounds present in a ....Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined these systems and limited prospect for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel natural compounds present in a range of weeds and crop plants.
The outcomes will be reduced herbicide inputs, and the development of a new group of natural herbicides to counteract the threat imposed by the development of herbicide resistance.
Read moreRead less
Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined minimum-tillage systems and heightened the limited prospects for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel nat ....Novel compounds as natural herbicides for weed management. The development by weeds of herbicide resistance has undermined minimum-tillage systems and heightened the limited prospects for development of new chemicals with different modes of actions through traditional methods. Such methods of searching for new herbicides are yielding diminishing returns and the associated costs are becoming prohibitive.
This project aims to develop herbicides by evaluating, isolating and identifying novel natural compounds present in a range of weeds and crop plants.
The outcomes will be reduced herbicide inputs, and the development of a new group of natural herbicides to counteract the threat imposed by the development of herbicide resistance.Read moreRead less
Characterising annual ryegrass (Lolium rigidum) in Australia. Annual rye grass (ARG) defies modern chemical technologies through evolving resistance. Agriculture has prospect of no herbicide options for ARG control in 10 years. Traditional approaches do not provide sustainable answers. A novel study of fundamental factors influencing competitiveness of this species is warranted to achieve more strongly based management options. Benefits are a prototype for improving understanding of other weed s ....Characterising annual ryegrass (Lolium rigidum) in Australia. Annual rye grass (ARG) defies modern chemical technologies through evolving resistance. Agriculture has prospect of no herbicide options for ARG control in 10 years. Traditional approaches do not provide sustainable answers. A novel study of fundamental factors influencing competitiveness of this species is warranted to achieve more strongly based management options. Benefits are a prototype for improving understanding of other weed species, a stronger basis for determining management of Australia's worst temperate crop weed. Bringing together knowledge of ARG's genetic diversity, the role of endophyte and its allelopathic capabilities provides a powerful basis for unlocking the barriers to the control of this species.Read moreRead less
Putting smells into context: Using in vivo technologies to understand plant-insect odour signalling. How insects find host plants is central to understanding their basic ecology and management. We use a novel cross-disciplinary approach to target a key pest insect's responses to a host-plant, genetically modified to smell different. This insect pest, the cotton bollworm, costs the Australian economy millions in lost revenue every year. Reliance on insecticides to control insect pests is exacerba ....Putting smells into context: Using in vivo technologies to understand plant-insect odour signalling. How insects find host plants is central to understanding their basic ecology and management. We use a novel cross-disciplinary approach to target a key pest insect's responses to a host-plant, genetically modified to smell different. This insect pest, the cotton bollworm, costs the Australian economy millions in lost revenue every year. Reliance on insecticides to control insect pests is exacerbated by increasing insecticidal resistance and is a major economic, environmental and health concern. Our research will open the door to novel control strategies that use the natural odours of plants to reduce their attractiveness to insect pests.Read moreRead less