Defensive behaviours elicited by predator odours. Rats display a powerful anxiety responses when confronted with the odours of predators such as cats. This response may occur even though rats have never encountered an actual predator before. This project aims to investigate the nature of this anxiety and the nature of the stimuli that produce it. The outcomes should be a better understanding of the neural basis and pharmacology of anxiety states and the identification of novel chemicals that hav ....Defensive behaviours elicited by predator odours. Rats display a powerful anxiety responses when confronted with the odours of predators such as cats. This response may occur even though rats have never encountered an actual predator before. This project aims to investigate the nature of this anxiety and the nature of the stimuli that produce it. The outcomes should be a better understanding of the neural basis and pharmacology of anxiety states and the identification of novel chemicals that have powerful rodent repellent properties. Such chemicals may be of great use in domestic and agricultural contexts where rodents are pests.Read moreRead less
Integrated governance of water and coal seam gas. This project aims to evaluate the governance of the water effects on unconventional gas, to develop legal and policy principles for the integration of these effects in an effective, efficient and legitimate manner, and to investigate problems posed for integrated and polycentric governance, more generally. Australia must meet its unconventional gas needs without harming its water resources. The project is expected to deliver effective and legitim ....Integrated governance of water and coal seam gas. This project aims to evaluate the governance of the water effects on unconventional gas, to develop legal and policy principles for the integration of these effects in an effective, efficient and legitimate manner, and to investigate problems posed for integrated and polycentric governance, more generally. Australia must meet its unconventional gas needs without harming its water resources. The project is expected to deliver effective and legitimate outcomes for water, energy and potentially other social and environmental issues, aiming to establish Australia as a leader in sustainable water management.Read moreRead less
Deep Learning Attacks and Active Defences: A Cybersecurity Perspective. The belief that deep learning technology is imperative for economic development, military control, and strategic competitiveness has accelerated its development across the globe. However, experience has revealed the disappointing fact that deep learning models are vulnerable to a range of security attacks. Hence, a series of methodologies and defence strategies will be devised that make deep learning systems robust to these ....Deep Learning Attacks and Active Defences: A Cybersecurity Perspective. The belief that deep learning technology is imperative for economic development, military control, and strategic competitiveness has accelerated its development across the globe. However, experience has revealed the disappointing fact that deep learning models are vulnerable to a range of security attacks. Hence, a series of methodologies and defence strategies will be devised that make deep learning systems robust to these attacks. The methodologies require analysing attack lifecycles to identify them in their early stages. With this knowledge, active defence methods and forensic strategies can be developed to ensure efficient defences and prevent further attacks. Moreover, the outputs will be generalisable to most deep learning services.Read moreRead less
Non-urban water governance: rethinking compliance and enforcement. This project aims to critically evaluate the practices and strategies of non-urban water compliance and enforcement in Australia and internationally, to identify and develop innovations for water governance. New law and policy knowledge is expected from its fusion of empirical data and regulatory theory. The project expects to advance applied regulatory theory by identifying improvements in compliance and enforcement to help solv ....Non-urban water governance: rethinking compliance and enforcement. This project aims to critically evaluate the practices and strategies of non-urban water compliance and enforcement in Australia and internationally, to identify and develop innovations for water governance. New law and policy knowledge is expected from its fusion of empirical data and regulatory theory. The project expects to advance applied regulatory theory by identifying improvements in compliance and enforcement to help solve environmental issues. It will also lead to policy reforms for delivering more effective, efficient and politically-acceptable compliance outcomes for non-urban water management that will benefit water regulators and the sustainability and productivity of Australia's agricultural industry.Read moreRead less
Balance and reinforcement: privacy and fairness in high intelligence models. The aim of this project is to develop a series of privacy preservation methods to achieve a new balance between privacy and fairness in highly accurate intelligence models. The main issue in achieving this goal is that high-accuracy intelligence technologies have resulted in significant privacy violations and are very vulnerable to issues of unfairness. This project will analyse the privacy risks associated with intelli ....Balance and reinforcement: privacy and fairness in high intelligence models. The aim of this project is to develop a series of privacy preservation methods to achieve a new balance between privacy and fairness in highly accurate intelligence models. The main issue in achieving this goal is that high-accuracy intelligence technologies have resulted in significant privacy violations and are very vulnerable to issues of unfairness. This project will analyse the privacy risks associated with intelligent systems and devise mechanisms to mutually reinforce both privacy and fairness based on the theoretical foundations laid by our analysis. These outcomes will enable model owners to effectively protect their intellectual property and offer services to users in a private, fair, and accurate manner.Read moreRead less
Reverse chemical proteomics: harnessing yeast display for drug discovery. This project aims to develop a technique that can rapidly identify the cellular protein targets of biologically active natural products. This project expects to provide fundamental biological and chemical insights into Australia's unique biodiversity that will facilitate the development of new therapeutic agents and agrochemicals based on leads provided by Nature. Expected outcomes of this project include an optimised and ....Reverse chemical proteomics: harnessing yeast display for drug discovery. This project aims to develop a technique that can rapidly identify the cellular protein targets of biologically active natural products. This project expects to provide fundamental biological and chemical insights into Australia's unique biodiversity that will facilitate the development of new therapeutic agents and agrochemicals based on leads provided by Nature. Expected outcomes of this project include an optimised and validated platform technology for accelerating drug discovery and development. This should substantially reduce the costs associated with fighting human and animal diseases, leading to improved health, productivity and quality of life.Read moreRead less
Microeconomic effects of Australian natural disasters. This project aims to describe and identify the effects of Australian natural disasters – such as the Black Saturday bushfires and the Brisbane floods – on important microeconomic outcomes, including health, education and employment. Natural disasters have profound economic and social effects on individuals and communities. This project intends to bring evidence on how disasters affect individuals and how the effects can be lessened. The proj ....Microeconomic effects of Australian natural disasters. This project aims to describe and identify the effects of Australian natural disasters – such as the Black Saturday bushfires and the Brisbane floods – on important microeconomic outcomes, including health, education and employment. Natural disasters have profound economic and social effects on individuals and communities. This project intends to bring evidence on how disasters affect individuals and how the effects can be lessened. The project expects to inform policy-makers on these critical issues by analysing field, survey and administrative data on individuals before and after past disasters.Read moreRead less
A peptide platform to fight pests threatening global food security. This project aims to develop a platform technology for the efficient design of new crop protection agents based on peptides to protect Australia’s food security. It will be first applied against the highly destructive fall armyworm, currently spreading alarmingly in Australia. The project is significant because insect pests cause huge economic and environmental impacts. Peptides are a new generation of crop protection agents tha ....A peptide platform to fight pests threatening global food security. This project aims to develop a platform technology for the efficient design of new crop protection agents based on peptides to protect Australia’s food security. It will be first applied against the highly destructive fall armyworm, currently spreading alarmingly in Australia. The project is significant because insect pests cause huge economic and environmental impacts. Peptides are a new generation of crop protection agents that are potentially more effective and sustainable than chemical pesticides. Expected outcomes are a new rapid response technology and associated lead molecules to protect against current and emerging pests. Major benefits are increased food security, improved crop yields and a more sustainable agriculture industry. Read moreRead less
Increasing Globalisation and its Economic Implications. This project will focus on globalisation and its economic implications. We will: (a) propose definitions and measure of the ?degree of globalization", (b) examine its relationship with the degree of uncertainty facing an economy, (c) study the effects of globalisation and uncertainty on productivity growth, (d) examine the effects of uncertainty on the economy and (f) provide empirical applications for the Australian economy. Our project wi ....Increasing Globalisation and its Economic Implications. This project will focus on globalisation and its economic implications. We will: (a) propose definitions and measure of the ?degree of globalization", (b) examine its relationship with the degree of uncertainty facing an economy, (c) study the effects of globalisation and uncertainty on productivity growth, (d) examine the effects of uncertainty on the economy and (f) provide empirical applications for the Australian economy. Our project will provide an important, innovative and comprehensive examination of globalization and its economic effects. In addition to making novel theoretical and empirical contributions, it will also facilitate meaningful analyses of policy issues in Australia.Read moreRead less
A novel approach to fighting fungal infections: targeted disruption of hydrophobin monolayers. Fungal infestations of important crops such as cotton cause large economic losses to Australian agriculture while in the medical sector, fungal infections are responsible for high levels of mortality in immunocompromised patients. Our research will provide a new approach to fighting fungal infections by targeting the hydrophobin proteins, which form a robust coating on fungal aerial structures, such as ....A novel approach to fighting fungal infections: targeted disruption of hydrophobin monolayers. Fungal infestations of important crops such as cotton cause large economic losses to Australian agriculture while in the medical sector, fungal infections are responsible for high levels of mortality in immunocompromised patients. Our research will provide a new approach to fighting fungal infections by targeting the hydrophobin proteins, which form a robust coating on fungal aerial structures, such as spores. This layer is critical for fungal growth and reproduction and confers water resistance and tolerance to harsh conditions. Our work seeks to develop reagents that can specifically block regions on the protein that are responsible for forming this coating.
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