Nuclear Sirtuins At The Interface Between Epigenetic Regulation And Human Cytomegalovirus Pathogenesis: A Proteomics Perspective
Funder
National Health and Medical Research Council
Funding Amount
$399,488.00
Summary
Human cytomegalovirus (HCMV) is a human pathogen that infects over 60% of the adult population, and is a major cause of birth defects causing permanent hearing and vision loss, and mental retardation. To investigate the critical involvement of host epigenetic factors, I will study the roles of sirtuins during HCMV infection. Through proteomic, genomic, microscopy, and bioinformatic techniques, I aim to further our understanding of viral pathogenesis, towards developing novel therapies.