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A Practical New Method Of Measuring Population Salt Intake
Funder
National Health and Medical Research Council
Funding Amount
$327,193.00
Summary
The World Health Organization has set a target for member countries to reduce salt intake by 30% by 2025. Key to this is measurement of population salt intake. Collection of 24-hour urine samples is the gold standard used to estimate salt intake but this method is burdensome. Collection of a single urine sample is an alternative method. This project will bring together all of the available data worldwide to assess the reliability of using a single urine sample to measure population salt intake.
Pre-clinical Evaluation Of The LSD1 Inhibitor HCI-2509: Defining The Biomarkers Of Sensitivity And The Mechanisms Of Resistance
Funder
National Health and Medical Research Council
Funding Amount
$340,068.00
Summary
Despite aggressive multi-modal treatment strategies, limited progress in the treatment of Ewing sarcoma (paediatric bone malignancy), has been achieved over the past 30 years. As such, the advent of novel and targeted therapeutics with favourable efficacy/toxicity profiles are eagerly awaited. This proposal will investigate the therapeutic utility of LSD1 inhibition as a treatment for Ewing sarcoma and the underlying mechanisms of sensitivity/resistance to this unique agent.
Novel Pathways Toward Improving Relapse Prediction In Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Relapse is a devastating problem in schizophrenia and our ability to predict when it occurs is still relatively poor. This project seeks to investigate a new method of tracking relapse by measuring speech and symptom changes across time. This novel design is supported by advanced data modelling methods to provide sensitive predictive ability. This project has the potential to significantly improve relapse prediction in schizophrenia and so support and increase beneficial outcomes for patients
Collaborating To Create Healthy Built Environments: Including Health In A Land Use Planning System
Funder
National Health and Medical Research Council
Funding Amount
$320,891.00
Summary
The way the built environment is planned and designed has a pervasive influence on health but how to translate that evidence into policy and practice is under-researched. Recent developments in NSW provide the opportunity to investigate how health is included across the business of a land-use planning system. This translational research uses a realist approach and policy analysis to unpack the influences on health being included (or not) at multiple levels of the system.