THE DETECTION AND MANAGEMENT OF DEMENTIA IN GENERAL PRACTICE.
Funder
National Health and Medical Research Council
Funding Amount
$499,977.00
Summary
This research aims to examine a new method and practice guidelines for detection of early dementia. General practitioners will be screened on their ability to diagnose and manage dementia and to distinguish it from other diseases. Patient outcomes - including quality of life, depression, and satisfaction with care and referral indicators - will be examined.
Cognitive Outcome And Therapeutic Interventions For Coronary Artery Disease.
Funder
National Health and Medical Research Council
Funding Amount
$392,104.00
Summary
Dementia is recognized as an increasingly important factor affecting quality of life as people age. Deaths from heart disease are declining, in part due to improved surgical techniques and to the use of less invasive methods to keep arteries open such as coronary stenting. It is now well known that 20 to 60% of patients experience some degree of impairment in thinking ability (cognitive impairment) after cardiac surgery, that this will persist in some of these individuals for years and may incre ....Dementia is recognized as an increasingly important factor affecting quality of life as people age. Deaths from heart disease are declining, in part due to improved surgical techniques and to the use of less invasive methods to keep arteries open such as coronary stenting. It is now well known that 20 to 60% of patients experience some degree of impairment in thinking ability (cognitive impairment) after cardiac surgery, that this will persist in some of these individuals for years and may increase the risk of long-term problems. Cognitive impairment affects people in many ways. While it is not yet known whether the occurrence of cognitive impairment predisposes to dementia, it is thought that Mild Cognitive Impairment (MCI) may do so. We propose to explore the link between MCI and Post Procedural Cognitive Deficit (PPCD) in patients with coronary disease from before the first point of objective diagnosis, i.e. prior to the coronary angiogram, and over a 12-month period, through and subsequent to further treatment interventions such as stenting or cardiac surgery. Our Pilot data suggest that PPCD does indeed occur after angiography, and we propose to identify how long this lasts, whether MCI predisposes to it and whether it is better to wait until it resolves before further interventions are undertaken. In this way we hope to identify the safest treatment strategy for patients with coronary disease that will minimize the occurrence of Cognitive Deficit and possibly longer-term cognitive changes after investigation and treatment for their symptoms.Read moreRead less
Understanding The Dynamics Of The Medical Workforce To Improve Population Health And Equity Of Access: The Australian Lo
Funder
National Health and Medical Research Council
Funding Amount
$2,278,544.00
Summary
The health workforce is now a key area of government policy. The ageing of the medical workforce, combined with more women entering medicine and changes in doctors preferences over their work-life balance, are all likely to have important effects on the ability of health care system to provide good quality and accessible health care. However, there is little knowledge or understanding of how and why doctors make decisions on how many hours they work, their location of work, including working in ....The health workforce is now a key area of government policy. The ageing of the medical workforce, combined with more women entering medicine and changes in doctors preferences over their work-life balance, are all likely to have important effects on the ability of health care system to provide good quality and accessible health care. However, there is little knowledge or understanding of how and why doctors make decisions on how many hours they work, their location of work, including working in rural and remote areas, and decisions to leave the medical workforce and retire. These decisions have important effects on the population�s access to health care and therefore on their health status and quality of care received. The aim of this research is to examine those factors influencing doctors� labour supply decisions through the establishment of the Australian Longitudinal Survey of Doctors (ALSD). The survey will track 5,500 doctors over an initial four year period. The research will provide a rigorous analysis of medical workforce decisions that underpin workforce distribution and the working patterns of doctors. The survey will be used to evaluate and simulate policy changes and provide important evidence to support future policy developments.Read moreRead less
Modelling The Economics Of The Australian Health Care System For Policy Analysis
Funder
National Health and Medical Research Council
Funding Amount
$3,500,000.00
Summary
The program will build a suite of economic models capable of providing timely relevant analysis of almost any major health policy option or issue, providing expertise in government and academia to use the kind of sophisticated quantitative tools of analysis common in sectors of the economy of an equivalent size to health. Through a PhD and postdoctoral program, it will increase capacity in quantitative health economics in Australia to answer key questions in health services, health promotion and ....The program will build a suite of economic models capable of providing timely relevant analysis of almost any major health policy option or issue, providing expertise in government and academia to use the kind of sophisticated quantitative tools of analysis common in sectors of the economy of an equivalent size to health. Through a PhD and postdoctoral program, it will increase capacity in quantitative health economics in Australia to answer key questions in health services, health promotion and illness prevention, developed with partners in government, clinicians and industry.Read moreRead less
Statistical Methods And Algorithms For Analysis Of High-throughput Genetics And Genomics Platforms
Funder
National Health and Medical Research Council
Funding Amount
$1,557,500.00
Summary
Through rapid advances in high-throughput -omics technologies, the number of phenotypes and the number of genotypes in gene mapping studies are or will be orders of magnitudes larger than in previous studies. Current algorithms and analysis methods have not kept up with the speed of data collection, nor has the training of qualified researchers. We will develop quantitative trait loci (fine) mapping analysis methods and bioinformatics algorithms and train (post)graduates in these research areas.
Cost Effectiveness Of Glucosamine Sulphate For Knee Arthritis (COGS)
Funder
National Health and Medical Research Council
Funding Amount
$448,791.00
Summary
A clinical trial, conducted in general practice, randomising 340 patients with symptomatic knee osteoarthritis to glucosamine sulphate or matching placebo tablets for 9 months. The main study outcomes will be knee pain, physical function and analgesia use. Analysis will be undertaken to identify characteristics associated with treatment responsiveness, such as high body mass index and structural disease severity. An economic analysis will be conducted alongside this trial.
Optimising Prevention And The Management Of Care For Australians With Or At Risk Of Serious And Continuing Chronic Illne
Funder
National Health and Medical Research Council
Funding Amount
$3,760,301.00
Summary
The project aims to study three prototype conditions - cardiovascular disease, diabetes and chronic obstructive pulmonary disease - in people aged 45 to 85 in the Sydney West Area Health Service and the Australian Capital Territory with a view to implementing and evaluating new models of care and developing policies that observe accurately the current state of the art technologies, discern the gaps in knowledge, locate the barriers to optimality and engage policy makers in practical proposals ab ....The project aims to study three prototype conditions - cardiovascular disease, diabetes and chronic obstructive pulmonary disease - in people aged 45 to 85 in the Sydney West Area Health Service and the Australian Capital Territory with a view to implementing and evaluating new models of care and developing policies that observe accurately the current state of the art technologies, discern the gaps in knowledge, locate the barriers to optimality and engage policy makers in practical proposals about how best to use the currently available resources to achieve better health outcomes.Read moreRead less