Blocking of the interfaces of polymeric ion sensors - implications for novel sensor applications. Control of the transmembrane fluxes of polymeric ion sensors represents a paradigm shift that has revolutionised the use of these analytically important devices. This project will develop and characterise innovative methods for controlling these fluxes by using blocked interfaces, and this has important ramifications for the development of robust and reliable sensors, as well as novel biosensors.
Helium droplets: a nanoscale laboratory for studying intermolecular bonding and chemical reactivity. This type of research requires a rather complicated apparatus capable of creating a stream of helium droplets, embedding molecules and interrogating their properties using laser spectroscopy. The apparatus built in Sydney is the only one capable of this in Australia and using this new apparatus we will create many novel, bizarre and intriguing aggregates of molecules and atoms. The project involv ....Helium droplets: a nanoscale laboratory for studying intermolecular bonding and chemical reactivity. This type of research requires a rather complicated apparatus capable of creating a stream of helium droplets, embedding molecules and interrogating their properties using laser spectroscopy. The apparatus built in Sydney is the only one capable of this in Australia and using this new apparatus we will create many novel, bizarre and intriguing aggregates of molecules and atoms. The project involves cutting-edge scientific methods and will shift the boundaries of can-do science in the laser laboratory at the University of Sydney and in Australia in general.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100135
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
Federated single crystal X-ray structural analysis facility. X-ray crystallography is the most widely applied method for the determination of three-dimensional molecular structures. These structures range in size from small systems such as materials and pharmaceuticals through to large biological structures such as proteins. This application will provide a multidisciplinary facility covering the structural characterisation needs of chemistry, pharmacy, biology, and medicine. This will position l ....Federated single crystal X-ray structural analysis facility. X-ray crystallography is the most widely applied method for the determination of three-dimensional molecular structures. These structures range in size from small systems such as materials and pharmaceuticals through to large biological structures such as proteins. This application will provide a multidisciplinary facility covering the structural characterisation needs of chemistry, pharmacy, biology, and medicine. This will position local universities for key scientific breakthroughs that benefit the Australian community by providing improved healthcare technologies, and processes. Furthermore, access to this world-class facility will provide state-of-the-art training for undergraduate, postgraduate and postdoctoral researchers.Read moreRead less
Quantum Unimolecular Reaction Dynamics: from Isolated Molecules to Protein-Embedded Chromophores. The outcomes of this research will (a) enhance the reputation of Australian science internationally,(b) develop highly skilled research personnel with core capabilities in computational chemistry who can contribute to Australian industry, (c) lead to more accurate modelling of atmospheric ozone depletion phenomena, and (d) improve our understanding of the most common cellular imaging tool - the Gree ....Quantum Unimolecular Reaction Dynamics: from Isolated Molecules to Protein-Embedded Chromophores. The outcomes of this research will (a) enhance the reputation of Australian science internationally,(b) develop highly skilled research personnel with core capabilities in computational chemistry who can contribute to Australian industry, (c) lead to more accurate modelling of atmospheric ozone depletion phenomena, and (d) improve our understanding of the most common cellular imaging tool - the Green Fluorescent Protein - with spinoff benefits for molecular biology research in Australia through the potential for design of new fluorescent proteins.Read moreRead less
The role of water uptake in novel all solid-state polymeric ion sensors. This research will enable the development of robust all solid-state polymeric ion sensors based on unplasticized copolymers. Significantly, the physical and chemical robustness of these copolymer ion sensors will allow their widespread use in new and exciting analytical applications, e.g., in-situ analysis of environmental samples in submersible instruments, clinical analysis of whole blood, in-vivo use of miniaturized ele ....The role of water uptake in novel all solid-state polymeric ion sensors. This research will enable the development of robust all solid-state polymeric ion sensors based on unplasticized copolymers. Significantly, the physical and chemical robustness of these copolymer ion sensors will allow their widespread use in new and exciting analytical applications, e.g., in-situ analysis of environmental samples in submersible instruments, clinical analysis of whole blood, in-vivo use of miniaturized electrodes in biological media, especially single cells and minute samples in biology and forensic science, etc. Extensive use of neutron characterization techniques aligns strongly this project with the new OPAL reactor to be commissioned in 2007.Read moreRead less
Probing the internal contacts of all solid-state polymeric ion sensors. The results of this research will enable the development of robust and reliable all solid-state polymeric ion sensors. These sensors will enable solutions to significant environmental problems such as soil salinity and acidity, and may pave the way for new and exciting analytical applications, e.g., miniaturized implantable sensors for in-vivo use, microfluidics and Forensic Science, single blood droplet clinical analyzers, ....Probing the internal contacts of all solid-state polymeric ion sensors. The results of this research will enable the development of robust and reliable all solid-state polymeric ion sensors. These sensors will enable solutions to significant environmental problems such as soil salinity and acidity, and may pave the way for new and exciting analytical applications, e.g., miniaturized implantable sensors for in-vivo use, microfluidics and Forensic Science, single blood droplet clinical analyzers, rugged solid contact ion sensors for use in submersible oceanographic analyzers, etc. The research will develop a unique in-situ neutron reflectometry technique for the study of electrochemical interfaces, providing scientific opportunities for the new Australian Replacement Research Reactor.Read moreRead less
Probing the interfaces of electrochemical sensors. The nanostructured surfaces of electrochemical sensors for iron, mercury and cadmium will be characterised by using a range of state-of-the-art surface analysis techniques. Whilst electrochemical sensors are extremely valuable in monitoring of trace metals in the aquatic environment, a knowledge of the surface chemical physics of the systems is vital in order to widen their use in analytical/environmental chemistry. This project will derive a u ....Probing the interfaces of electrochemical sensors. The nanostructured surfaces of electrochemical sensors for iron, mercury and cadmium will be characterised by using a range of state-of-the-art surface analysis techniques. Whilst electrochemical sensors are extremely valuable in monitoring of trace metals in the aquatic environment, a knowledge of the surface chemical physics of the systems is vital in order to widen their use in analytical/environmental chemistry. This project will derive a universal model for the surface chemistry and physics of electrochemical sensors, enabling environmental scientists to develop unique sensor methods for studying the speciation of environmentally important trace metals such as those mentioned above.Read moreRead less
Thin Films of Oxide Ceramics. Aluminium oxide films are used extensively in the Australian industries of Protective & Decorative Coatings (examples include door-knobs and cutting-tools). The industry will be offered a remarkably simple process for preparation of high quality films. In the microelectronic industry, the uses of aluminium oxide films as a dielectric alternative to silicon dioxide has just started to emerge world - wide and this new process would make a dramatic impact with commerci ....Thin Films of Oxide Ceramics. Aluminium oxide films are used extensively in the Australian industries of Protective & Decorative Coatings (examples include door-knobs and cutting-tools). The industry will be offered a remarkably simple process for preparation of high quality films. In the microelectronic industry, the uses of aluminium oxide films as a dielectric alternative to silicon dioxide has just started to emerge world - wide and this new process would make a dramatic impact with commercial benefits for Australia. Read moreRead less
Special Research Initiatives - Grant ID: SR0354775
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Australian Synchrotron Sciences Network. A synchrotron light source is a critical piece of infrastructure for a modern technological nation. In 2001, the Victorian government announced that it would contribute $157M towards the establishment of a national synchrotron facility, becoming operational in 2007. The research performed at such a facility is exceedingly diverse, and often the underpinning technology is the only point of contact for users. A vibrant and productive facility requires a tra ....Australian Synchrotron Sciences Network. A synchrotron light source is a critical piece of infrastructure for a modern technological nation. In 2001, the Victorian government announced that it would contribute $157M towards the establishment of a national synchrotron facility, becoming operational in 2007. The research performed at such a facility is exceedingly diverse, and often the underpinning technology is the only point of contact for users. A vibrant and productive facility requires a transparent interface between the scientist and the technology. This Network will set up the communication channels within the user base, and between the users and the facility development program.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775551
Funder
Australian Research Council
Funding Amount
$550,000.00
Summary
Integrated Advanced X-ray Diffraction Facility. The new equipment will provide a unique facility for single crystal, powder and thin film structure elucidation using X-ray diffraction techniques. No other techniques have the capabilities in structure determination of materials at an atomic level which are necessary for delivering applications in nano-technology, health care products, amongst many fields, for the benefit for the community at large. The facility will foster a more innovative resea ....Integrated Advanced X-ray Diffraction Facility. The new equipment will provide a unique facility for single crystal, powder and thin film structure elucidation using X-ray diffraction techniques. No other techniques have the capabilities in structure determination of materials at an atomic level which are necessary for delivering applications in nano-technology, health care products, amongst many fields, for the benefit for the community at large. The facility will foster a more innovative research culture and provide excellent research training at the highest international level, and will provide a platform to maximise access to the new Opal Research Reactor and Australian Synchrotron.Read moreRead less